ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Molecular Classifier of Antibody-Mediated Rejection Is a Better Predictor of Histologic Rejection Than a Corresponding Transcript Set and Is Further Improved When Combined with Classifiers of Rejection Syndromes.

    K. Famulski, P. Halloran.

    University of Alberta, Edmonton, AB, Canada

    Molecular and histologic changes in graft rejection are not completely specific, often being induced by injuries and other diseases. We examined various methods for using…
  • 2017 American Transplant Congress

    IVIG + Rituximab as Desensitization Agents to Reduce Donor Specific Antibodies and Improve Transplant Rates in Highly Hla Sensitized (HS) Awaiting Deceased Donor Kidney Transplantation.

    R. Najjar, E. Huang, A. Vo, J. Cho, S. Louis, A. Hang, A. Peng, S. Jordan.

    Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

    Background: HS patients are at risk for development of donor specific antibodies (DSA) and the persistence of DSA is associated with poor graft outcomes. Rituximab,…
  • 2017 American Transplant Congress

    Clostridium difficile Infection in Intestinal Transplant Recipients.

    V. Goldenberg,1 A. Berbel,2 J. Camargo,1 J. Simkins.1

    1Medicine, Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL; 2Medicine, University of Miami Miller School of Medicine, Miami, FL

    Background: Clostridium difficile infection (CDI) data in intestinal transplant (ITx) recipients is lacking. This study was performed to evaluate prevalence, risk factors, treatments and outcomes…
  • 2017 American Transplant Congress

    MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.

    A. Yang,1 C. Zhou,2 D. Li,3 W. Ju,1 Z. Guo,1 L. Wu,1 A. Hu,1 Y. Ma,1 D. Wang,1 X. Zhu,1 X. He.1

    1Organ Transplantation Center, The First Affiliated Hospital of Sun Yat -sen University, Guangzhou, Guangdong, China; 2Gastroenterology Unit, Massachusetts General Hospital, Boston, MA; 3Ophthalmology, Schepens Research Institute, Boston, MA

    There is an urgent need to develop sensitive and specific biomarkers for the early diagnosis of candida infection in transplanted patients. miRNAs and lncRNAs are…
  • 2017 American Transplant Congress

    TIMP-3 Plays a Key Regulatory Role in the Cleavage of E-Cadherin and Has an Essential Protective Function in Hepatic IRI.

    T. Fujii, S. Duarte, R. Busuttil, A. Coito.

    Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA

    Liver ischemia-reperfusion injury (IRI) remains a challenging problem in clinical orthotopic liver transplantation. Tissue inhibitor of metalloproteinases-3 (TIMP-3), an extracellular matrix-associated protein, has been linked…
  • 2017 American Transplant Congress

    Angioplasty versus Stent in the Treatment of Transplant Renal Artery Stenosis.

    L.-X. Chen,1 G. Fananapazir,2 H. Bang,3 M. Gandhi,1 M. Alnimri,1 B. Gallay,1 A. De Mattos.1

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Radiology, UC Davis Medical Center, Sacramento, CA; 3Biostatistics, UC Davis School of Medicine, Davis, CA

    Objective: To compare restenosis rates and treatment efficacy between percutaneous transluminal angioplasty and stent placement in the treatment of transplant renal artery stenosis.Methods: We conducted…
  • 2017 American Transplant Congress

    Long-Term Immunosuppression Adherence After Kidney Transplant and Relationship to Allograft Histology.

    E. Lorenz, B. Smith, F. Cosio, N. Shah, P. Groehler, J. Verdick, W. Park, M. Stegall.

    Mayo Clinic, Rochester

    Background: Loss of Medicare coverage for immunosuppression 3 years after kidney transplant may be associated with increased nonadherence. The goal of this study was to…
  • 2017 American Transplant Congress

    The Value of Protocol Biopsy at Third Month After Kidney Transplant: A Single-Center Cohort Analysis.

    R. Rosado-Canto, C. Barrientos-Aguilar, I. Parra-Avila, L. Marino, M. Arvizu-Hernandez, N. Uribe-Uribe, L. Morales-Buenrostro.

    Departament of Nephrology and Transplant, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico

    Introduction: In spite of publications reporting higher detection of subclinical rejection (SR) with protocol biopsies in kidney transplant (KT) recipients there is no recommendation with…
  • 2017 American Transplant Congress

    Induction in the Elderly: A Comparison of Basiliximab versus Rabbit Anti-Thymocyte Globulin After Kidney Transplantation.

    J. Lee, E. Liu, M. Aull, S. Kapur.

    Weill Cornell Medical Center, New York, NY

    Background: Although it is well established that kidney transplant (KT) in the elderly is beneficial and safe, there is limited literature on the appropriate choice…
  • 2017 American Transplant Congress

    Optimizing Survival Outcomes for Advanced Age Patients Undergoing Liver Transplant.

    J. Balogh, K. Lunsford, D. Nguyen, E. Gravis, A. Saharia, C. Mobley, S. Gordon Burroughs, O. Cercio, D. Victor, H. Monsour, A. Gaber, R. Ghobrial.

    Houston Methodist Hospital, Houston, TX

    ObjectivesAge at liver transplant (LT) is progressively increasing and is a known risk factor for mortality. We sought to evaluate preTx predictors for mortality among…
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