ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Subclinical Histologic Findings Are Observed in 25% of Stable Adult Liver Transplant Recipients (ALTRs) Screened for Immunosuppression Withdrawal (ISW): OPTIMAL (NCT02533180).

    S. Chandran,1 M. Abecassis,2 J. Levitsky,2 S. Feng,3 A. Humar,4 J. Emond,5 G. Klintmalm,6 A. Demetris,4 K. Much,7 L. Sun,1 A. Priore,8 D. Ikle,7 N. Bridges,8 M. DesMarais,1 B. Burrell,9 J. Markmann.10

    1ITN, San Francisco; 2Northwestern, Chicago; 3UCSF, San Francisco; 4UPMC, Pittsburgh; 5Columbia, New York; 6Baylor, Dallas; 7Rho, Chapel Hill; 8NIAID/NIH, Bethesda; 9ITN, Bethesda; 10MGH, Boston

    OPTIMAL is a 6-center ISW study in non-autoimmune, non-HCV ALTRs ≥3 yrs post-transplant (tx). Studies have shown a correlation between portal inflammation associated with tissue…
  • 2017 American Transplant Congress

    Plasma Cell Hepatitis in Primary Sclerosing Cholangitis Patients: 15-Year Experience at a Transplant Center.

    J. Putra,1 T. Schiano,2 M. Fiel.3

    1Pathology, Icahn School of Medicine at Mount Sinai, New York, NY; 2Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY

    Background: Plasma cell hepatitis (PCH) is an uncommon liver graft dysfunction which occurs in liver transplant (LT) recipients of different etiologies other than autoimmune hepatitis.…
  • 2017 American Transplant Congress

    Semi-Automated Pre-Donation Computed Topography (CT) Cortical Renal Volume to Predict Kidney Function in Live Kidney Donors 2 Years Following Donation.

    L.-X. Chen,1 G. Fananapazir,2 R. Benzl,2 M. Corwin,2 S. Stewart,3 C. Troppmann.4

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Radiology, UC Davis Medical Center, Sacramento, CA; 3Biostatistics, UC Davis School of Medicine, Davis, CA; 4Transplant Surgery, UC Davis Medical Center, Sacramento, CA

    Objective: To evaluate whether volume of the remnant kidney based on pre-donation CT and donor age correlates with post-donation 2-year renal function in live kidney…
  • 2017 American Transplant Congress

    Usefulness of Multi-Detector Computed Tomography (MDCT) Scanning as a Replacement for Diethylenetriamine Pentaacetic Acid (DTPA).

    H. Lee,1 W. Han,1 K. Huh,2 M. Kim,2 S. Kim,2 Y. Kim,2 Y. Yoon.1

    1Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Transplantation Surgery, Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Objective: Diethylenetriamine pentaacetic acid (DTPA) and multi-detector computed tomography (MDCT) can predict postoperative estimated glomerular filtration rate (eGFR) in a live kidney donor. Accordingly, we…
  • 2017 American Transplant Congress

    Seasonality of Mortality and Graft Failure Among Kidney Transplant Recipients in the US.

    B. Astor,1 M. Melamed,2 D. Mandelbrot,1 A. Djamali.1

    1University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY

    The incidence of mortality in the general population is significantly higher in winter than in summer. It is unknown whether such a seasonal difference exists…
  • 2017 American Transplant Congress

    State Law Restrictions on HIV Positive-to-Positive Transplantation.

    S. Rasmussen,1 A. Glazier,2 A. Cash,1 M. Henderson,1 B. Boyarsky,1 K. Miller,3 S. Schoettes,4 D. Segev,1 C. Durand.1

    1JHU, Baltimore; 2NEOB, Waltham; 3HIV Medicine Association, Arlington; 4Lambda Legal, Chicago

    Background In 1984 the National Organ Transplant Act banned the recovery of organs from HIV-positive (HIV+) individuals. In 2013 the HIV Organ Policy Equity (HOPE)…
  • 2017 American Transplant Congress

    Willingness of Canadian ESRD Patients to Consider Transplant Tourism.

    J. Gill, G. Gill, Y. Joffres, C. Rose, J. Gill, L. Russell, A. Levin, C. Richardson.

    UBC, Vancouver, Canada

    BackgroundTransplant tourism refers to travel for transplantation involving organ trafficking or transplant commercialism, and is associated with poor outcomes. While some characteristics of transplant tourists…
  • 2017 American Transplant Congress

    Uptake of Extracellular Mitochondria Activates Human Endothelial Cells That Stimulate Alloreactive Effector T Cell Responses.

    T. Brennan,1 F. Feng,1 L. Lin,1 M. Song,1 Q.-J. Li,2 A. Kirk,1,2 H. Xu.1

    1Surgery, Duke University, Durham, NC; 2Immunology, Duke University, Durham, NC

    Introduction: Vascular endothelial cells (VECs), the initial barrier between host immunity and donor allograft tissue, play a critical role in allograft rejection. We investigated the…
  • 2017 American Transplant Congress

    Current Treatments for Small Hepatocellular Carcinoma: A Network Meta-Analysis of Randomized Controlled Trials.

    Z. Guo, Z. Zheng, X. He, G. Chen.

    The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Purpose: Numerous randomized controlled trials (RCTs) concerning treatments for small hepatocellular carcinoma (HCC) have been reported. Herein, we conducted a network meta-analysis integrating current evidence…
  • 2017 American Transplant Congress

    Precise Antibody Characterization Using Multiple Solid Phase Assay Platforms Is Critical for Accurate Virtual Crossmatching.

    D. Li,1 O. Timofeeva,1 M. Awwad,1 C. Cody,2 S. Najjar,2 S. Rosen-Bronson.1

    1Histocompatibility Laboratory, MedStar Georgetown University Hospital, Washington, DC; 2MedStar Heart Institute, Washington Hospital Center, Washington, DC

    Purpose: Virtual crossmatch (VXM) has been utilized in heart transplant (txp) for more than a decade. Many labs base the VXM solely on single antigen…
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