ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Early Results of the UK REVIVE Trial for Ex-Vivo Liver Warm Blood Perfusion of DCD and DBD Livers Using the Portable Organ Care System (OCS™) Liver Technology.

    D. Vijayanand, F. Zahreldeen, J. Kingston, S. Farid, T. Mdlongwa, A. Ramsden, S. Willis, C. Moriarty, M. Attia.

    Hepatobiliary and Transplant Surgery, The Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Purpose:TheOCS Liver REVIVE Trial is a single-arm prospective trial to evaluate the safety and performance of OCS™ Liver system to preserve and assess DCD and…
  • 2017 American Transplant Congress

    Lower Incidence of DSA-Induced Chronic Antibody-Mediated Rejection in Abo-Incompatible Renal Transplantation.

    M. Okada,1 Y. Watarai,1 K. Iwasaki,2 K. Futamura,1 T. Hiramitsu,1 M. Tsujita,1 N. Goto,1 S. Narumi,1 T. Kobayashi.2

    1Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; 2Transplant Surgery, Aichi Medical University, Nagakute, Japan

    <INTRODUCTION>Current progress in immunosuppressive therapy has successfully controlled ABO-incompatibility in renal transplantation, although donor specific HLA antibody (DSA) is still insurmountable. Our in vitro experiments…
  • 2017 American Transplant Congress

    HLA-DR Based Murine Transplant Model for Studying Collagen Type V Autoimmunity in Chronic Allograft Rejection.

    V. Agashe, Y. Zhou, E. Jankowska-Gan, W. Burlingham.

    Dept. of Surgery/Transplant Division, UW Madison, Madison, WI

    Background: In lung and heart transplant patients, chronic rejection manifests as fibro-obliteration of airways and vessels resulting in bronchiolitis obliterans syndrome (BOS) or cardiac allograft…
  • 2017 American Transplant Congress

    Outcomes with Kidney Transplant from Deceased Donors with Acute Kidney Injury and Prolonged Cold Ischemia Time: UNOS Analysis.

    G. Dube, S. Mohan, M. Chiles.

    Nephrology, Columbia University Medical Center, New York, NY

    Longer cold ischemia time (CIT) is associated with an increased risk of delayed graft function and may increase the risk of graft failure. Kidneys with…
  • 2017 American Transplant Congress

    Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.

    M. So,1 A. Morris,1,2 C. Bell,2 A. Humar,1 S. Husain.1

    1University Health Network, Toronto, ON, Canada; 2Sinai Health System, Toronto, ON, Canada

    IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…
  • 2017 American Transplant Congress

    In Clinic Systems to Address Adherence Barriers Decrease Late Allograft Rejection for Kidney Transplant Patients.

    D. Hooper, C. Varnell, Jr., K. Rich, D. Dahale, J. Huber, A. Pai, A. Modi.

    Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background: Patient-identified barriers to taking immunosuppressive medications are associated with rejection and allograft loss in kidney transplant patients, yet interventions targeting adherence barriers are rarely…
  • 2017 American Transplant Congress

    Time to Kidney Transplantation Following Live Donor Candidate Referral.

    K. Kumar, J. Tonascia, A. Muzaale, A. Poon, T. Purnell, J. Garonzik-Wang, E. King, M. Bowring, A. Massie, D. Segev.

    Surgery, Johns Hopkins University, Baltimore, MD

    Kidney transplant candidates have utilized novel methods to identify and refer willing donors; however, delays or barriers to actually achieving live donor kidney transplantation are…
  • 2017 American Transplant Congress

    Anti-CD40 mAb Promotes Kidney Immunoregulatory Capacity in NHP Transplants by Altering Kidney Tubular Cell (TEC) Expression of CD40 and IL-6.

    J. Arp,1 Y. Ma,1 H. Yang,2 A. El Warrak,1 A. Haig,1 W. Liu,1 K. Reimann,3 P. Luke,1 Z. Zhang,1 D. Rothstein,4 A. Jevnikar.1

    1Medicine, Pathology & Microbiology & Immunology, Western University, London, ON, Canada; 2Sichuan Provincial Hospital, Chengdu, Sichuan, China; 3University of Massachusetts, Boston, MA; 4University of Pittsburgh, Pittsburgh, PA

    Treatment of cynolmolgus monkey (NHP) renal transplant recipients with a combination of 2 rhesus-mouse chimeric α-CD45RB (r6G3R1; 6G3) and α-CD40 (r2C10R4; 2C10) mAbs increased circulating…
  • 2017 American Transplant Congress

    Outcome of Living Donor Transplantation in Pediatric Recipients Over the Last Three Decades by Era: An Analysis of UNOS Database.

    V. Whittaker, M. Laftavi, Z. Acun, R. Gruessner, A. Gruessner.

    Surgery, State University New York, Syracuse, NY

    Background: Living donor is the potential solution to organ shortage. This retrospective analysis of UNOS database evaluates the outcome of living donor transplantation across 4…
  • 2017 American Transplant Congress

    Impact of Alemtuzumab Induction on Hepatitis C Treatment Outcomes Post-Renal Transplantation.

    S. Jonchhe, J. Husson, J. Casale, R. Adekunle, P. Mathur, J. Gripshover, B. Ravichandran.

    University of Maryland Medical Center, Baltimore, MD

    BackgroundDirect-acting antiviral agents (DAAs) have improved treatment outcomes for Hepatitis C virus (HCV). Given high rates of treatment success with few side effects, eradication of…
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