2017 American Transplant Congress
KDPI and Small (<20 kg) Pediatric Kidney Donors.
1Seattle Children's Hospital, Seattle; 2Scientific Registry of Transplant Recipients, Minneapolis
Use of small (≤20 kg) donor kidneys in pediatric candidates has declined under the new kidney allocation system (KAS), from 5.0% of pediatric kidney-alone transplants…2017 American Transplant Congress
CCR7+CD8+ T Cell Suppresses Effector T Cell Related Allo-Immune Responses in Kidney Transplant Recipients.
Internal Medicine, Seoul St. Mary's Hospital, Seoul, Korea
Background; Previously reports showed that CCR7+CD8+ T cells have suppressive effect on various pathogenic immune cells. The aim of this study is to investigate the…2017 American Transplant Congress
Dual Costimulatory Blockades Failed to Achieve Transplant Tolerance Despite Induction of Mixed Chimerism in NHPs.
Background: Our previous studies showed that substantial deletion of CD8+ memory T cells (TMEM) was necessary to induce mixed chimerism (MC) and allograft tolerance when…2017 American Transplant Congress
10 Years or More of Follow Up After Total Pancreatectomy and Intra Portal Islet Auto Transplantation (TP/IAT) for Treatment of Chronic Pancreatitis, Is It a Durable Operation?
Surgery, University of Minnesota, Minneapolis
Background: Total pancreatectomy and intra-portal islet cell auto-transplantation (TP/IAT) is increasingly being utilized for the management of chronic pancreatitis (CP), the benefits being removal of…2017 American Transplant Congress
Hepatic Ischemia Reperfusion Injury After Liver Transplantation Is Associated with Acute Kidney Injury.
Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that severity of IRI correlates with…2017 American Transplant Congress
Alcohol-Induced Hepatic Cirrhosis Is Rising Among Young Adults.
Background: Alcoholic cirrhosis is a common indication for liver transplantation. Recent population studies have shown no change in the overall prevalence of alcohol use, but…2017 American Transplant Congress
Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Recipients (rc) and Suppress Recipient T-Cell (T) Response Against Donor Antigen.
[Introduction] Recent advances of immunosuppressive regimens have decreased rejection rate and improved rc survival of IT. MDSC are potent immature myeloid cells capable of suppressing…2017 American Transplant Congress
Prolonged Survival with Co-Stimulatory Blockade Based Immunosuppression in Pig-to-Primate Liver Xenotransplantation.
Massachusetts General Hospital, Boston, MA
Background: Since the first attempt in 1968, survival following pig-to-baboon liver xenotransplantation (LXT) has been limited to <9-days due to a lethal coagulopathy. To improve…2017 American Transplant Congress
Higher Mortality Among Candidates Who Refused Increased-Infectious Risk Kidney Offers.
Increased infectious risk donors (IRD) are younger and healthier than most deceased donors, but IRD kidneys are discarded at higher rates despite potential benefit to…2017 American Transplant Congress
The New Kidney Allocation System in France Meets it's Targets: Improving Age and HLA DR-QD Matching for Young Adults.
Direction Medicale et Scientifique, Agence de la Biomedecine, Saint-Denis, France
A new KAS was implemented in France as of February 2015, resulting from an intensive 3 yrs-simulation work in interaction with KTx advisory committee and…
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