2017 American Transplant Congress
Circulating Inflammatory Factors in Deceased Organ Donors Result in Innate Immune Activation.
Surgery, Duke University, Durham, NC
Background: Superior outcomes of living-donor compared to deceased-donor transplants may be related to increased graft immunogenicity at the time of transplant. Donor brain death results…2017 American Transplant Congress
Outcomes Following Colectomy in Kidney Transplant Recipients.
Kidney transplant recipients (KTR), like the general population, often require surgical procedures for non-transplant related issues. Given the need for lifelong immunosuppression and the physiologic…2017 American Transplant Congress
Increased Use of Donation After Cardiac Death Donors Increases Access to Transplantation without Adverse Effect on Outcomes.
UT/Methodist University Hospital, Memphis, TN
IntroductionAs the transplant community discusses redistricting to address potential imbalance in loco-regional liver distribution, liver transplant programs will need to identify strategies to maximize access…2017 American Transplant Congress
Deceased Donors with a History of IV Drug Use and Donor Derived Hepatitis C Virus.
1OPTN Ad Hoc Disease Transmission Advisory Committee, Richmond, VA; 2UNOS, Richmond
Introduction:In 2015, the CDC reported a 172% increase in heroin-related deaths from 2010 to 2013. Deceased donors with IV drug use (IVDU) are at increased…2017 American Transplant Congress
Anti-Angiotensin Type 1 Receptor Antibodies Associate with Rejection in Simultaneous Pancreas and Kidney Transplant and Pancreas Transplant Alone Recipients.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Background: Anti-angiotensin type 1 receptor antibodies (AT1R Ab) have been found to have a strong association with antibody mediated rejection (Reinsmoen et al, Transpl 2010;…2017 American Transplant Congress
TFR:TFH Cell Ratio Correlates with Anti-Donor Germinal Center Reactivity and Donor-Specific Antibody Formation Following Transplantation.
Emory Transplant Center, Emory University School of Medicine, Atlanta, GA
Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Although short-term outcomes are excellent, long-term allograft survival rates remain inadequate. It…2017 American Transplant Congress
Mouse FCs May Contain Lymphoid Progenitor Cells That Have the Capacity to Generate B and T Cells In Vivo.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY
CD8+/TCR- facilitating cells (FCs) are a rare bone marrow-derived cell population that enhances engraftment of hematopoietic stem cells (HSC) in major histocompatibility complex disparate recipients…2017 American Transplant Congress
Primary Graft Dysfunction After Pediatric Heart Transplant.
Pediatric Cardiology, Washington University School of Medicine, St. Louis, MO
Background: Primary graft dysfunction (PGD), as defined by ISHLT Consensus Guidelines, has been associated with worse outcomes in adult heart transplant recipients, even in patients…2017 American Transplant Congress
Emergency Department Utilization Among Kidney Transplant Recipients in the United States.
Background:Single center studies suggest that kidney transplant (KTx) recipients have a high rate of emergency department (ED) utilization, and ED visits are associated with graft…2017 American Transplant Congress
APOL1 Genotype Does Not Affect Donor Renal Function Post Live Kidney Donation.
Background: Apolipoprotein-L1 (APOL1) risk variants have emerged as a predictor of renal disease in individuals of African Ancestry (AA). The effect of APOL1 risk variants…
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