2017 American Transplant Congress
A Novel, Dose-Adjusted Tacrolimus Trough Concentration (TTC) Model for Prediction and Variance Estimation.
Given that a high tacrolimus (tac) intrapatient variability (IPV) increases the risk for a poor kidney transplant (tx) outcome, some experts advocate routine IPV monitoring…2017 American Transplant Congress
The Efficacy and Safety of Plaquenil in Kidney Transplants Patients with Lupus.
Background: Hydroxychloroquine, also known as Plaquenil ( PLQ) is an antimalarial drug with immunomodulatory action. Recent studies have demonstrated a protective effect of PLQ in…2017 American Transplant Congress
Detection of Shared and Distinct Gene Expression Signatures in Tissue and Urine During Acute Rejection of Kidney Grafts.
A major goal of the Clinical Trials in Organ Transplantation (CTOT) studies is the identification of biomarkers that predict or diagnose acute graft rejection in…2017 American Transplant Congress
Cardiovascular Disease in Japanese Kidney Transplant Recipients.
Urology, Tokyo Women's Medical University, Tokyo, Japan
BackgroundGlobally, among kidney transplant recipients (KTRs), cardiovascular diseases (CVDs) have been the most frequent cause of death with a preserved transplant kidney function, referred to…2017 American Transplant Congress
The Effects of Aspirin on Major Adverse Cardiac Events and Kidney Allograft Outcomes: A Meta-Analysis.
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN
BACKGROUND: The use of aspirin in chronic kidney disease patients has been shown to reduce myocardial infarction but may increase major bleeding. However, its effects…2017 American Transplant Congress
Age-Related Differences in Gene Expression Among Kidney Allografts with Normal Histology and Calcineurin Inhibitor Nephrotoxicity.
Background Most biomarker research first occurs in adult populations, with consequent extrapolation to children. However, age-related differences may impact gene expression, such as variations in…2017 American Transplant Congress
Patient Outcomes Following the Disappearance of Donor Specific Antibody in Crossmatch Positive Simultaneous Liver-Kidney Transplant Recipients.
Background: Simultaneous liver and kidney transplantation (SLKT) remains as the gold standard for patients with chronic renal and liver diseases. Pre-transplant donor-specific antibody (DSA) to…2017 American Transplant Congress
National Variation in Liver Transplant Immunosuppression in the U.S..
Variation in immunosuppression (ISx) for liver transplant (LTx) across US programs has not been described. We examined a novel database integrating national registry and pharmacy…2017 American Transplant Congress
Identification of a Stable Gene Signature of Transplant Tolerance to Liver Allograft by Meta-Analysis.
Transplant tolerant to a liver graft display a specific blood cell transcriptional pattern but results from six different studies were not consistent, raising the question…2017 American Transplant Congress
Optimizing Support for Living Kidney Donors: Insights from a Prospective Study.
1Yale U, New Haven; 2U Pennsylvania, Philadelphia; 3Northwestern U, Chicago
PurposeTo assess how potential living kidney donors (LKDs) perceived support from the transplant team and areas for improvement.MethodsWe conducted a prospective, longitudinal study of individuals…
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