ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Transplantation of Chimeric Cells of Myoblast and Mesenchymal Stem Cell Origin for Restoration of Muscle Function.

    M. Siemionow, E. Szilagyi, J. Cwykiel, A. Domaszewska-Szostek, A. Heydemann, J. Garcia-Martinez.

    University of Illinois at Chicago, Chicago

    Background: Allogeneic stem cell therapies aim to restore muscle tissue after traumatic loss or muscular dystrophies. Limited engraftment due to rejection is a major challenge.…
  • 2017 American Transplant Congress

    Update of a Placebo-Controlled Trial of C1 Esterase Inhibitor for Prevention of Antibody Mediated Rejection (ABMR) in Highly-HLA Sensitized Patients.

    A. Vo, J. Choi, A. Peng, K. Lim, L. Varanasi, R. Najjar, E. Huang, D. Puliyanda, S. Jordan.

    Kidney Transplant, Cedars-Sinai Medical Center, LA, CA

    INTRODUCTION: Desensitization (DES) strategies focus primarily on antibody reduction using IVIG, rituximab ± PLEX to prevent DSA-induced ABMR and rebound B-cell activity. Pathologic features of…
  • 2017 American Transplant Congress

    The Impact of the Donor Risk Index on Tumor Free Survival in Patients Undergoing Liver Transplantation with Hepatocellular Carcinoma.

    D. Moonka,1 S. Nagai,2 A. Harper, R. Salgia.1

    1Division of Gastroenterology, Henry Ford Health System, Detroit, MI; 2Transplant Institute, Henry Ford Health System, Detroit, MI; 3Research Department, United Network for Organ Sharing, Richmond, VA

    In this study, we look at the impact of donor quality on tumor free survival in patients undergoing liver transplant (LT) with hepatocellular carcinoma (HCC)…
  • 2017 American Transplant Congress

    Comparison of Local Recurrence Rates Between Endhole vs Anti-Reflux Catheters in Patients Undergoing DEB-TACE for Solitary LR-5 HCC Tumors.

    A. Arepally, L. Stein, R. Shrestha, M. Tully, S. Citron, A. Cherian, H. Pollinger, M. Bosley, R. Raymond.

    Division of Interventional Radiology, Piedmont Healthcare, Atlanta, GA; Piedmont Transplant Institute, Piedmont Healthcare, Atlanta, GA

    PurposeTo compare local recurrence rates (LRR), tumor response rates, and dose delivered between standard endhole catheters (EC) versus anti-reflux catheters (AR) in patients who underwent…
  • 2017 American Transplant Congress

    KDPI Obscures Trends in Absolute Donor Risk.

    N. Salkowski, S. Gustafson, A. Wey, J. Snyder.

    Scientific Registry of Transplant Recipients, Minneapolis, MN

    The kidney donor profile index (KDPI) is commonly used to measure deceased donor kidney quality based on the kidney donor risk index (KDRI) (Rao, et…
  • 2017 American Transplant Congress

    Correlation of Donor Clinical and Histopathological Characteristics with Graft Function in Kidney Transplant Recipients.

    M. Zachariah,1 C. Yip,1 M. Zachariah, I. Mallawaarachchi,2 A. Dweivedi,2 S. Patel,4 A. Gundroo,1 J. Tomaszewski,1 L. Lin,1 C. Shirley.1

    1Medicine, SUNY at Buffalo, Buffalo, NY; 2Biostatistics and Epidemiology, Texas Tech University, El Paso, TX; 3Pathology, SUNY at Buffalo, Buffalo, NY; 4Surgery, SUNY at Buffalo, Buffalo, NY

    Background: There is lack of consensus in the perceived accuracy of frozen biopsy interpretation. Interobserver variability in assessment of pre-implantation biopsies limits its value to…
  • 2017 American Transplant Congress

    Validation of a Novel Computational Approach for Predicting HLA Immunogenicity Based on Quantification of Structural and Surface Electrostatic Potential Differences Between Donor and Recipient HLA.

    V. Kosmoliaptsis,1 C. Kling,2 M. Robb,3 D. Collett,3 J. Bradley,1 C. Taylor,1 D. Kabelitz,2 D. Mallon.1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2University of Kiel, Kiel, Germany; 3NHS Blood and Transplant, Bristol, United Kingdom

    Background: Our preliminary work indicates that donor HLA immunogenicity in kidney and haematopoietic stem cell transplantation can be predicted by comparative assessment of donor and…
  • 2017 American Transplant Congress

    Mycophenolic Acid Needs Ca2+ to Exert Its Anti-inflammatory Action via Shedding of Toll-Like Receptor4 and Tumor Necrosis Factor Receptor 1.

    J. Kim,1 W. Yang,1 C. Baek,1 N. Han,2 S.-K. Park.1

    1Division of Nephrology, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Asan Institute for Life Science, Seoul, Republic of Korea

    Background Mycophenolic acid (MPA) has been used for many years to prevent transplantation rejection. Recently, it has been investigated for its anti-inflammatory effects. MPA can…
  • 2017 American Transplant Congress

    Nox4 and Oxidative Stress Mediate TGF-β1 Induced Human Kidney Proximal Cell Apoptosis in Ischemic Reperfusion Injury.

    S.-H. Yoon,1 S. Cho,1 D.-I. Kim,1 S.-R. Yoon,1 W.-M. Hwang,1 S.-L. Yu,2 J. Kang.2

    1Internal Medicine, Konyang University, Deajeon, Republic of Korea; 2Pharmacology, Konyang University, Daejeon, Republic of Korea

    AimsIschemia/reperfusion injury, resulting from hypoxic damage within a graft, is the leading cause of cell death and graft rejection. In this study, we investigated whether…
  • 2017 American Transplant Congress

    The Feared Five Fungal Infections in Kidney Transplant Recipients: 20-Year Experience at a Midwestern Center.

    S. Parajuli, A. Wick, S. Pandeya, B. Astor, J. Smith, A. Djamali, D. Mandelbrot.

    University of Wisconsin, Madison, WI

    Invasive fungal infections (IFI) are increasing in kidney transplant recipients (KTR). Here we present our experience with five feared IFIs in KTR transplanted between 01/01/1994…
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