2017 American Transplant Congress
Long-Term Outcome of Antibody-Mediated Rejection Due to Pre-Existing vs. De Novo DSA in Kidney Allograft Recipients.
BackgroundAntibody-mediated rejection (ABMR) can occur in patients with pre-existing anti-HLA donor-specific antibodies (DSA) or in patients who develop de novo DSA. However, how these processes…2017 American Transplant Congress
Prospective Randomized Trial for Predicting CMV Infection According to Baseline CMV-Specific T-Cell Immunity in Kidney Transplant Patients.
Background: Despite the use of either anti-viral prophylaxis (PF) or preemptive (PE) therapy given based on donor/recipient IgG-serostatus, Cytomegalovirus (CMV) reactivation persists after kidney transplantation…2017 American Transplant Congress
A Novel 3-Dimensional Culture System Enables In Vitro Study of Human Bone Marrow Plasma Cells.
Purpose: Historically, in vitro study of human plasma cells (PCs) has been greatly limited by their short survival (48-72 hrs). Therefore, systems that maintain viability…2017 American Transplant Congress
Current Practice and Ethical Dimensions of Implementing APOL1 Testing into Living Donor Evaluation: A National Survey.
1Northwestern University, Chicago; 2Mayo Clinic, Rochester
BackgroundAfrican American (AA) live kidney donors (LKDs) have an even greater risk of kidney failure than European American live donors. Apolipoprotein 1 (APOL1) gene variants…2017 American Transplant Congress
Disease Progression on Neoadjuvant Chemotherapy Is a Strong Predictor of Recurrence for Pediatric Hepatoblastoma.
1Surgery, Baylor College of Medicine, Houston; 2Surgery, Texas Children's Hospital, Houston
Purpose. In addition to peri-operative chemotherapy, proper triage between orthotopic liver transplantation (OLT) and partial hepatectomy (PH) is critical to limiting disease recurrence in pediatric…2017 American Transplant Congress
Antidepressant Medication Use Before and After Kidney Transplant: Implications for Post-Transplant Outcomes.
Limited data are available on the implications of antidepressant medication use in kidney transplant recipients.We examined a novel database wherein national transplant registry identifiers for…2017 American Transplant Congress
In Vivo Administration of Plerixafor in Humans Mobilizes Bone Marrow Resident Plasma Cells That Demonstrate Apoptosis in Both Bone Marrow and Peripheral Blood.
1University of Cincinnati, Cincinnati; 2Cincinnati Children's, Cincinnati; 3Duke, Durham
Plasma-cell (PC) targeted therapies can reduce HLA sensitization. However, bone marrow (BM) niche resident plasma cells (BMNRPC) demonstrate resistance to proteasome inhibitor (PI) therapy. Plerixafor…2017 American Transplant Congress
Harnessing Scientific and Technological Advances to Improve Equity in Kidney Allocation Policies.
To increase the likelihood of finding a compatible donor, kidney allocation systems prioritize highly sensitized patients to counterbalance the impact of HLA allo-sensitization and preclude…2017 American Transplant Congress
Preliminary Results of Clinical Normothermic Ex Vivo Liver Perfusion in a North American Setting.
Outcomes of a first clinical normothermic machine perfusion (NMP) UK liver trial demonstrated feasibility and clear safety, with improved liver function when compared to standard…2017 American Transplant Congress
Truth in Pathology: Autopsy Findings in Lungs Declined for Transplantation.
Healthy lungs are scarce among available organ donors who are becoming progressively older and have increasing numbers of comorbidities. Selection criteria that include excellent oxygenation…
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