2017 American Transplant Congress
BK Polyoma Virus and Malignancy: Cause or Co-Incidence?
Henry Ford Transplant Institute, Detroit, MI
BackgroundThe WHO agency for cancer research has classified BKV as "possibly carcinogenic".The etiological role of BKV in human cancer, however,remains controversial.We present 5 cases of…2017 American Transplant Congress
Impact of Race on Selection of the Living Donor Candidate.
Surgery, University of Pennsylvania, Philadelphia, PA
Background It has been reported that African-Americans (AA) living kidney donors have an increased risk of ESRD versus non-Hispanic whites (NHW). To date, it is…2017 American Transplant Congress
Longer Pre-Transplant Dialysis Exposure Is More Frequent in Living Donor Kidney Transplantation (LDTX) Involving Lower Income Donor and Recipients and Is Associated with an Increased Risk of LDTX Failure.
Background: Pre-emptive transplantation is known to be associated with superior LDTX outcomes, but the impact of pre-transplant (pre-TX) dialysis exposure on LDTX outcomes are less…2017 American Transplant Congress
Long-Term Outcomes of Renal Function in Pediatric Living Related Intestinal Transplantation.
1Surgery, UIC, Chicago, IL; 2Pediatrics, UIC, Chicago, IL; 3Surgery, Baylor University, Texas
Background: Renal function after organ transplantation is affected by several factors. The use of calcineurin inhibitors has a direct impact on the kidney. Material and…2017 American Transplant Congress
Ganciclovir Resistant Cytomegalovirus Infection in Abdominal Tansplant Recipients.
University of Wisconsin Hospital and Clinics, Madison
Purpose: Single center evaluation of ganciclovir-resistant cytomegalovirus (GR-CMV) incidence, treatment and outcomes.Methods: Review of adult abdominal transplant (aSOT) recipients from 1/1/1995-12/31/2015 with documented GR-CMV infection.Results:…2017 American Transplant Congress
Risk Factor for Hepatitis E Virus Infection Among Solid-Organ-Transplant Patients.
Genotype 3 and 4 hepatitis E virus (HEV) infections are prevalent in developed countries and can cause chronic hepatitis, cirrhosis, and extra-hepatic manifestations among solid-organ-transplant…2017 American Transplant Congress
Lymphoid Isolation as an Adjuvant Maneuver for Belatacept-Based Immunotherapy.
Purpose: Belatacept targets de novo alloimmune responses with minimal off target effects in renal transplantation, though adjuvant therapy is required for control of costimulation-blockade resistant…2017 American Transplant Congress
Generation of Autologous CMV and EBV-Specific T-Cell Lines from Seronegative Patients for Cell Therapy of Opportunistic Infections Following Kidney Transplantation.
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) reactivations after kidney transplant are associated with substantial morbidity, especially in seronegative patients. Adoptive immunotherapy using virus-specific T cells…2017 American Transplant Congress
Non-Human Primate Auto-Immune Responses to Col V, Kα-1Tubulin and Vimentin Are P2X7R Dependent.
1Surgery, University of Wisconsin, Madison, WI; 2Medicine, University of Wisconsin, Madison, WI
Background: Auto-immune responses to Collagen type V (ColV) have been associated with coronary artery disease and lung or heart transplant rejection in humans and murine…2017 American Transplant Congress
Increased T Cell Exhaustion in Dialysis Patients.
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
Infection is a major complication post-transplantation. Evaluating the immune system prior to transplant may allow better optimization of immunosuppression dose. T cell exhaustion has been…
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