ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Living Kidney Donors: Battling High Attrition Rates During Evaluation Process.

    J. Verbesey, A. Bacigalupo, A. Gilbert, A. Li, C. Zuttermeister, M. Grafals, J. Moore, B. Javaid, P. Abrams, S. Ghasemian, M. Cooper.

    MedStar Georgetown Transplant Institute, Washington DC

    With an ever increasing kidney waiting list, a major goal is to expand living donor transplantation (LD). LD increases volume and provides higher quality, longer…
  • 2017 American Transplant Congress

    Combination αCD28+αCD40 Costimulation Blockade Attenuates Acute and Chronic Rejection in Non-Human Primates.

    N. O'Neill, T. Zhang, W. Sun, G. Braileanu, X. Cheng, I. Tatarov, W. Hassanein, A. Azimzadeh, R. Pierson.

    University of Maryland School of Medicine, Baltimore, MD

    Purpose: Monotherapy using αCD28 or αCD40 antibodies significantly prolongs graft survival but does not induce tolerance in non-human primates (NHP). Here, we evaluate the relative…
  • 2017 American Transplant Congress

    Evolution of Health Related Quality of Life (HRQOL) in Kidney Donors.

    H. Ibrahim,1 D. Berglund,1 S. Jackson,2 A. Matas.1

    1U of MN, Mpls; 2M Health, Mpls

    Most living donors (LDs) enjoy excellent HRQOL after donation. However, most studies addressing HRQOL in this group have ascertained HRQOL related outcomes only at one…
  • 2017 American Transplant Congress

    Delayed Renal Implantation Improves Survival Following Simultaneous Liver-Kidney Transplantation in High Acuity Recipients.

    K. Lunsford,1 V. Agopian,2 A. Saharia,1 J. Balough,1 C. Mobley,1 S. Gordon-Boroughs,1 H. Gritsch,2 H. Podder,1 R. Knight,1 G. Danovitch,2 X. Li,1 A. Gaber,1 R. Busuttil,2 R. Ghobrial.1

    1Houston Methodist Hospital, Houston, TX; 2David Geffen School of Medicine at UCLA, Los Angeles, CA

    OBJECTIVES:Simultaneous liver-kidney transplantation (SLKT) improves survival for liver transplant (LT) recipients with renal dysfunction (RD); however, simultaneous transplant risks KT futility in high acuity recipients.…
  • 2017 American Transplant Congress

    Women Are Delisted for Being Too Sick for Liver Transplant More Frequently Than Men.

    G. Cullaro, J. Lai.

    University of California - San Francisco, San Francisco, CA

    Background: Women (W) with cirrhosis awaiting liver transplantation (LT) experience higher rates of waitlist mortality than men (M). We aimed to understand the impact of…
  • 2017 American Transplant Congress

    Release of HMGB1 in Serum and Urine of Brain-Death Donors Is Associated with Delayed Graft Function (DGF) of the Kidney.

    A. Zmijewska,1 J. Chen,1 J. Locke,2 J. Zmijewski,1 R. Mannon.1

    1Medicine, University of Alabama at Birmingham, Birmingham, AL; 2Surgery, University of Alabama at Birmingham, Birmingham, AL

    Delayed kidney graft function (DGF) following a kidney transplant is associated with worse graft survival and higher rejection risk. Risk factors for DGF have been…
  • 2017 American Transplant Congress

    Autologous Expanded Tregs and Porcine Hematopoietic Cells to Prolong Xenogeneic Pig Skin Graft Acceptance in Baboons.

    J. Stern,1 S. Kofman,1 P. Alonso-Guallart,1 E. Berglund,1 M. Danton,1 J. Weiner,1 D. Ayares,2 R. Hawley,1 K. Yamada,1 D. Sachs,1 M. Sykes,1 A. Griesemer.1

    1Columbia Center for Translational Immunology, Columbia University, New York, NY; 2Revivicor, Blacksburg, VA

    Background: Mixed chimerism (MC) has been shown to induce tolerance to allogeneic organs and has shown promise for application to xenotransplants, although long-term tolerance has…
  • 2017 American Transplant Congress

    Donor Age Is the Most Important Predictor of Longterm Graft Function in Simultaneous Pancreas-Kidney Transplantation from Donors After Cardiac Death.

    J. Chen,1 D. Mikhail,1,2 H. Sharma,3 A. Hijazi,1 D. Nap,1 L. Stitt,4 J. Jevnikar,5 M. Cooper,6 P. Luke,1,2 A. Sener.1,2

    1Schulich School of Medicine and Dentistry, London, Canada; 2Division of Urology, Department of Surgery, Western University, London, London, Canada; 3Division of General Surgery, Department of Urology, Western University, London, Canada; 4LW Stitt Statistical Services, London, Canada; 5Faculty of Engineering and Architectural Sciences, Ryerson University, Toronto, Canada; 6Georgetown University, Washington

    STUDY PURPOSE: We analyzed data from UNOS to determine the effects of donor age, donor BMI, and organ cold ischemic time on DCD-SPK graft outcomes.METHODS:…
  • 2017 American Transplant Congress

    Analysis of Outcomes in High Risk Kidney Transplants.

    E. Liu, M. Aull, J. Lee, S. Kapur.

    Kidney and Pancreas Transplantation, NewYork-Presbyterian Weill Cornell Medical Center, New York, NY

    Background: The new kidney allocation system implemented in 12/2014 utilizes estimated post-transplant survival scores (EPTS) and kidney donor profile index (KDPI) to optimize recipient survival…
  • 2017 American Transplant Congress

    Laparoscopic Sleeve Gastrectomy Improves Renal Transplant Candidacy and Posttransplant Outcomes in Morbidly Obese Patients.

    Y. Kim, A. Jung, V. Dhar, J. Tadros, R. Alloway, A. Shields, S. Woodle, T. Diwan.

    Surgery, University of Cincinnati, Cincinnati, OH

    BACKGROUND: Morbid obesity remains a barrier to kidney transplantation (KT) and is associated with increased delayed graft function (DGF), graft loss, and wound complications. Laparoscopic…
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