ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Improved Outcomes After Liver Transplantation from Controlled DCD Donors with Normothermic Regional Perfusion.

    G. Oniscu, F. Hunt, W. Herries, I. Currie, A. Sutherland, C. Beattie, E. Thomson.

    Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom

    Background: Normothermic regional perfusion (NRP) is currently explored as a method to recover organs from Maastricht category I-III Donors after circulatory death (DCD). This study…
  • 2017 American Transplant Congress

    Belatacept for Chronic Antibody-Mediated Rejection in Kidney Transplantation.

    D. Kumar,1 G. Gupta,1 J. Reeve,2 P. Sanghi,1 S. Bobba,1 M. Levy,1 C. Bhati,1 P. Kimball,1 H. Fattah,1 A. King,1 H. Massey,1 P. Halloran.2

    1Virginia Commonwealth University, Richmond; 2Alberta Transplant Applied Genomics Center, Edmonton, Canada

    Background: Chronic antibody mediated rejection (cAMR) is a major cause of long-term kidney transplant (KT) loss. Antibody or immune cell depletional therapies have unclear efficacy…
  • 2017 American Transplant Congress

    Macrophage Specific Deletion of RhoA Inhibits Fractalkine Signaling and Abrogates Chronic Rejection of Cardiac Allograft.

    M. Kloc, Y. Liu, W. Chen, X. Li, R. Ghobrial.

    Surgery, Houston Methodist Hospital and Research Institute, Houston

    Objective. Chronic rejection of transplanted organs remains unresolved issue in organ transplantation. The chronic rejection is the most common cause of graft loss within 10…
  • 2017 American Transplant Congress

    Donor Warm Ischemic Time >80min Is an Important Predictor of Kidney Graft Survival from Donors After Cardiac Death.

    J. Chen,1 D. Mikhail,2 H. Sharma,3 A. Hijazi,1 D. Nap,1 L. Stitt,4 J. Jevnikar,5 M. Cooper,6 P. Luke,2 A. Sener.2

    1Schulich School of Medicine & Dentistry, London, Canada; 2Urology, Western University, London, Canada; 3General Surgery, Western University, London, Canada; 4LW Stitt Statistical Services, London, Canada; 5Engineering, Ryerson University, Toronto, Canada; 6Georgetown University, Washington

    We analyzed UNOS data to determine how donor warm ischemic time (WIT), donor BMI, donor hypertension (dHTN), cold ischemic time (CIT), and vasopressin use in…
  • 2017 American Transplant Congress

    High Mortality in Transplant Recipients Associated with Coccidioidomycosis Derived from Organ Donors.

    N. Jeyakumar,2 N. Neidlinger,3 M. Salvatore,3 C. Brown,4 T. Carpenter,3 M. Fung,1 P. Chin-Hong.1

    1Department of Medicine, University of California, San Francisco, San Francisco, CA; 2Department of Medicine, University of Miami Miller School of Medicine, Miami, FL; 3Donor Network West, San Ramon, CA; 4Decision Patterns, Oakland, CA

    Purpose Coccidioidomycosis (CI) occurs in 4-9% of solid organ recipients in endemic areas, resulting in 30-63% mortality. CI can be transmitted directly via transplantation, but…
  • 2017 American Transplant Congress

    Outcomes of Infrainguinal Revascularization in Renal Transplant Patients.

    R. Craig-Schapiro, B. Nejim, M. Malas.

    Department of Surgery, Johns Hopkins Medical Institutes, Baltimore, MD

    Objective: While there have been a number of studies suggesting poor outcomes of lower extremity revascularization in patients with end-stage renal disease (ESRD), little is…
  • 2017 American Transplant Congress

    Is Reluctance to Accept Younger Kidney Donors Justified?

    H. Ibrahim,1 D. Berglund,1 S. Jackson,2 A. Matas.1

    1U of MN, Mpls; 2M Health, Mpls

    Transplant centers are often reluctant to accept young kidney donors because of long-term concerns regarding reduced renal mass and because they have not yet reached…
  • 2017 American Transplant Congress

    Mesenchymal Stem Cells Suppress T Cell Proliferation and Improve Allograft Survival in a Nonhuman Primate Transplant Model.

    S. Kim, D. Mathews, L. Higginbotham, C. Breeden, C. Larsen, A. Adams.

    Emory Transplant Center, Emory University, Atlanta, GA

    Background: The clinical implementation of costimulation blockade (CoB) provides long-term benefit to transplant recipients, with the short-term drawback of increased acute rejection. Cellular therapies are…
  • 2017 American Transplant Congress

    Bariatric Surgery Prior to Living Kidney Donation: A Solution to Expand the Donor Pool.

    M.-T. Nguyen, D. Carpenter, A. Mathur, J. Van Bever, R. Sandoval, L. Ratner.

    Department of Surgery, Columbia University, New York, NY

    Background: Living donor kidney donation rates have declined. Meanwhile, the number of morbidly obese people is increasing. They are frequently turned down for donation at…
  • 2017 American Transplant Congress

    IVIg+Rituximab Desensitization (DES) Combined with Alemtuzumab (ATZ) Induction Does Not Increase Risk for Viral Infections (VIs) and Associated Complications in HLA-Sensitized (HS) Kidney Transplant Patients (KTx Pts).

    S. Ge, B.-H. Shin, J. Mirocha, D. Thomas, M. Chu, E. Rodriguez, C. Chao, A. Petrosyan, O. Galera, A. Vo, J. Choi, A. Peng, J. Kahwaji, S. Jordan, M. Toyoda.

    Transplant Immunology Laboratory, Biostatistics Core and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Background: VIs represent significant morbidity factors in KTx pts. DES followed by KTx with ATZ induction increased successful Tx rates in HS pts, but may…
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