2017 American Transplant Congress
Immunosuppressive Regimen Modification Approaches in BK Nephropathy – A Comparative Study.
Department of Medicine, University of Maryland Medical Center, Baltimore, MD
The optimal approach for IS reduction in renal transplant recipients with BKN is not well defined. A number of clinical and in vitro studies suggest…2017 American Transplant Congress
Impact of Post Kidney Donation Gout on eGFR and Kidney Stones.
Compared to matched non donor controls, living kidney donors have a higher rate of hyperuricemia early post donation (Kasiske,Am J Kidney Dis,2016) and a higher…2017 American Transplant Congress
The Impact of Marginal Factors on the Postoperative Kidney Function of Complex Living Donors for Kidney Transplantation.
Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan
BackgroundMedically complex living donors with marginal factors are increasing.MethodsBetween January 2008 and May 2015, 639 living donors for kidney transplantation were included. Marginal factors for…2017 American Transplant Congress
A Study on Gene Expression of the Protective Effect of Nitric Oxide Releasing Nanofiber in Rat Renal Ischemia-Reperfusion Injury.
1Kyung Hee University, Seoul, Korea; 2Kwanwoon University, Seoul, Korea
Objective: Renal ischemia-reperfusion injury (IRI) is very important issue in kidney transplantation. Nitric oxide (NO) was well known to be a protector of IRI. The…2017 American Transplant Congress
Eight Years of Low-Dose Valganciclovir; Evaluating the Incidence and Risk Factors of CMV in Kidney Transplant Recipients.
Kidney Transplant, Brigham and Women's Hostpial, Boston, MA
Introduction: Cytomegalovirus (CMV) remains one the most clinically relevant and frequent post-transplant infections. Despite the availability of effective antiviral drugs, CMV continues to be of…2017 American Transplant Congress
Kidney Transplantation in HCV+ Recipients in a New Era of Diagnostics and Therapeutics.
Duke University Medical Center, Durham, NC
BackgroundHepatitis-C infected persons (HCV+) evaluated for kidney transplantation receive rigorous staging of their liver disease, often including liver biopsy. Meanwhile, studies have shown that despite…2017 American Transplant Congress
Inhibition of Bruton Tyrosine Kinase Blocks Sensitization in Response to Allogeneic Skin Transplantation and Prolong Skin Graft Survival.
Surgery, University of California, Los Angeles, CA
Antibody mediated rejection and donor specific antibodies are important causes of both early (hyperacute) and late (chronic) graft loss. Bruton tyrosine kinase (Btk) is required…2017 American Transplant Congress
Recipient iNOS Deficiency Reduces Spontaneous Kidney Allograft Acceptance by Accelerating Allograft Loss.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
Nitric oxide (NO) production by inducible nitric oxide synthase (iNOS), encoded by NOS2, is a hallmark of the innate immune axis, and is typically associated…2017 American Transplant Congress
Suppression of T Cell Proliferation by CpG-Activated B Cells Depends on Granzyme-B and Cell-Cell Contact, but Not on IL-10.
Background: Our previous studies document the potent capacity of regulatory B cells (Bregs) to mitigate allograft immunity. However, we have been largely unsuccessful in demonstrating…2017 American Transplant Congress
Ex-Vivo Mitomycin-C Exposure Reduced Immunogenicity and Prolonged Survival of Islets by Suppressing the Secretion of Multiple Chemotaxis Factors.
Background. Strategies to reduce immunogenicity of islets, and to prevent activation of pro-inflammatory events are essential to successful islet engraftment. We previously demonstrated that ex-vivo…
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