Am J Transplant, Volume 17, Suppl 3 Archives - Page 127 of 181 - ATC Abstracts

2017 American Transplant Congress
HLA-DR Based Murine Transplant Model for Studying Collagen Type V Autoimmunity in Chronic Allograft Rejection.
V. Agashe, Y. Zhou, E. Jankowska-Gan, W. Burlingham.
Dept. of Surgery/Transplant Division, UW Madison, Madison, WI
Background: In lung and heart transplant patients, chronic rejection manifests as fibro-obliteration of airways and vessels resulting in bronchiolitis obliterans syndrome (BOS) or cardiac allograft…
2017 American Transplant Congress
Outcomes with Kidney Transplant from Deceased Donors with Acute Kidney Injury and Prolonged Cold Ischemia Time: UNOS Analysis.
G. Dube, S. Mohan, M. Chiles.
Nephrology, Columbia University Medical Center, New York, NY
Longer cold ischemia time (CIT) is associated with an increased risk of delayed graft function and may increase the risk of graft failure. Kidneys with…
2017 American Transplant Congress
Effect of Academic Detailing with Prescribers as an Antimicrobial Stewardship Intervention in Solid Organ Transplant Patients.
M. So,¹ A. Morris,^1,2 C. Bell,² A. Humar,¹ S. Husain.¹
¹University Health Network, Toronto, ON, Canada; ²Sinai Health System, Toronto, ON, Canada
IntroductionThe role of academic detailing (AD) as an antimicrobial stewardship intervention, where the steward meets the prescribers in their practice setting to provide personal educational…
2017 American Transplant Congress
In Clinic Systems to Address Adherence Barriers Decrease Late Allograft Rejection for Kidney Transplant Patients.
D. Hooper, C. Varnell, Jr., K. Rich, D. Dahale, J. Huber, A. Pai, A. Modi.
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background: Patient-identified barriers to taking immunosuppressive medications are associated with rejection and allograft loss in kidney transplant patients, yet interventions targeting adherence barriers are rarely…
2017 American Transplant Congress
Time to Kidney Transplantation Following Live Donor Candidate Referral.
K. Kumar, J. Tonascia, A. Muzaale, A. Poon, T. Purnell, J. Garonzik-Wang, E. King, M. Bowring, A. Massie, D. Segev.
Surgery, Johns Hopkins University, Baltimore, MD
Kidney transplant candidates have utilized novel methods to identify and refer willing donors; however, delays or barriers to actually achieving live donor kidney transplantation are…
2017 American Transplant Congress
Anti-CD40 mAb Promotes Kidney Immunoregulatory Capacity in NHP Transplants by Altering Kidney Tubular Cell (TEC) Expression of CD40 and IL-6.
J. Arp,¹ Y. Ma,¹ H. Yang,² A. El Warrak,¹ A. Haig,¹ W. Liu,¹ K. Reimann,³ P. Luke,¹ Z. Zhang,¹ D. Rothstein,⁴ A. Jevnikar.¹
¹Medicine, Pathology & Microbiology & Immunology, Western University, London, ON, Canada; ²Sichuan Provincial Hospital, Chengdu, Sichuan, China; ³University of Massachusetts, Boston, MA; ⁴University of Pittsburgh, Pittsburgh, PA
Treatment of cynolmolgus monkey (NHP) renal transplant recipients with a combination of 2 rhesus-mouse chimeric α-CD45RB (r6G3R1; 6G3) and α-CD40 (r2C10R4; 2C10) mAbs increased circulating…
2017 American Transplant Congress
Outcome of Living Donor Transplantation in Pediatric Recipients Over the Last Three Decades by Era: An Analysis of UNOS Database.
V. Whittaker, M. Laftavi, Z. Acun, R. Gruessner, A. Gruessner.
Surgery, State University New York, Syracuse, NY
Background: Living donor is the potential solution to organ shortage. This retrospective analysis of UNOS database evaluates the outcome of living donor transplantation across 4…
2017 American Transplant Congress
Impact of Alemtuzumab Induction on Hepatitis C Treatment Outcomes Post-Renal Transplantation.
S. Jonchhe, J. Husson, J. Casale, R. Adekunle, P. Mathur, J. Gripshover, B. Ravichandran.
University of Maryland Medical Center, Baltimore, MD
BackgroundDirect-acting antiviral agents (DAAs) have improved treatment outcomes for Hepatitis C virus (HCV). Given high rates of treatment success with few side effects, eradication of…
2017 American Transplant Congress
Life Threatening Disparities in Calculated MELD Due to Variation in Laboratory Methods within a UNOS Region.
E. Verna,¹ C. Connelly,¹ L. Dove,¹ J. Emond,¹ P. Adem,² N. Babic,³ J. Corsetti,⁴ J. Faix,⁵ J. Hayden,⁶ M. Lifshitz,⁷ M. Chiles,¹ S. Mohan,¹ H. Eldad,¹ A. Kratz.¹
¹CUMC, NY; ²WMC, NY; ³MSSM, NY; ⁴URMC, Rochester; ⁵MMC, NY; ⁶WCM, NY; ⁷NYU, NY
MELD was implemented as an objective measure to prioritize patients for liver transplant (LT). Accuracy and reproducibility of MELD is an essential assumption to ensure…
2017 American Transplant Congress
Proteomic Profiles of Deceased Donor Kidney Biopsies Obtained Prior to Transplantation Correlate with Allograft Function at One Year.
M. Kaisar,^1,2 L. van Dullemen,¹ Z. Akhtar,¹ H. Huang,¹ B. Kessler,² R. Ploeg.¹
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; ²Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
Introduction:Cerebral injury during Donation after Brain Death (DBD) will induce a systemic inflammatory response affecting immediate kidney function and survival posttransplantation. Assessment of donor organ…