ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Deceased Donor-Initiated Non-Simultaneous Extended Altruistic Donor Chains Through the Military Share Program.

    M. Rees,1,2 O. Ekwenna,1 E. Elster,3 A. Patel,3 D. Murtagh, Jr,1 A. Roth,4 K. Krawiec,5 J. Arrington,6 I. Ashlagi,4 J. Hawksworth.3

    1U Toledo, Toledo, OH; 2Alliance for Paired Donation, Perrysburg, OH; 3Walter Reed National Medical Center, Bethesda, MD; 4Stanford U, Palo Alto, CA; 5Duke U, Durham, NC; 6Buckeye Transplant, Findlay, OH

    Introduction: At a recent White House Summit on organ transplantation, the Department of Defense (DoD) announced that they would direct some Military Share deceased donor…
  • 2017 American Transplant Congress

    A Brief Frailty Assessment and Outcomes Among Candidates for Liver Transplantation.

    M. Serper, K. Dwinnells, T. Bittermann, K. Olthoff.

    Medicine, University of Pennsylvania, Philadelphia, PA; Surgery, Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA

    Introduction: As frailty correlates with post-transplant outcomes, brief frailty measures are needed in clinical practice to appropriately risk stratify LT candidates. We used an abbreviated…
  • 2017 American Transplant Congress

    Dual Targeting of Costimulation and Proteasome to Desensitize and Prolong Graft Survival of Sensitized Nonhuman Primates.

    J. Kwun,1 C. Burghuber,1 M. Manook,1 B. Ezekian,1 J. Park,1,2 K. Freishlag,1 J. Yoon,1 N. Iwakoshi,3 A. Farris,4 S. Knechtle.1

    1Surgery, Duke Transplant Center, Durham, NC; 2Surgery, Samsung Medical Center, Seoul, Korea; 3Surgery, Emory Transplant Center, Atlanta, GA; 4Pathology, Emory University, Atlanta, GA

    [Background] Pre-formed donor-specific anti-HLA antibodies (DSA) from prior transplantation, transfusion, or pregnancy affects a significant portion (35%) of patients awaiting a kidney transplant. Highly sensitized…
  • 2017 American Transplant Congress

    BK Virus, Cytomegalovirus and Epstein-Barr Virus Reactivation in Renal Transplant Patients: Results from a Large Multicenter Study.

    A. Blázquez-Navarro,1 C. Dang-Heine,1 M. Or-Guil,2 C. Bauer,3 T. Westoff,4 C. Hugo,5 P. Reinke,1 B. Sawitzki,1 N. Babel.1,4

    1Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany; 2Humboldt-Universität zu Berlin, Berlin, Germany; 3MicroDiscovery GmbH, Berlin, Germany; 4Medizinische Klinik I, Universitätsklinikum der Ruhr-Universität Bochum, Herne, Germany; 5Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus, Dresden, Germany

    The purpose of this study was to ascertain the prevalence and clinical implications of three of the most relevant opportunistic infections in kidney transplantation, namely…
  • 2017 American Transplant Congress

    De Novo, Non-Donor Specific HLA Antibodies Are Associated with Inferior Allograft Outcomes After Kidney and Simultaneous Kidney-Pancreas Transplantation.

    S. Hassan,1 G. Lucisano,1 E. Santos,2 D. McKeown,3 D. Goodall,1 A. Gueret-Wardle,1 A. McLean,1 P. Brooks,2 M. Willicombe,1 D. Taube.1

    1Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; 2Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom; 3Blood Transfusion, Imperial College Healthcare NHS Trust, London, United Kingdom

    Introduction: Donor specific antibodies [DSAs] occurring after transplantation are associated with poorer outcomes. However the significance of non-donor directed HLA antibodies [ndHLAs] after transplantation in…
  • 2017 American Transplant Congress

    Is Peri-Transplant Plasmapheresis Effective in the Prevention of Recurrence of FSGS?

    P. Verghese, M. Rheault, S. Chinnakotla, S. Jackson, A. Matas, B. Chavers.

    University of Minnesota, Minneapolis

    Many pediatric centers utilize a variety of protocols including scheduled plasmapheresis to prevent the dreaded recurrence of focal segmental glomerulosclerosis (FSGS) post-transplant. But the effectiveness…
  • 2017 American Transplant Congress

    Impact of Peri-Transplant Viral Upper Respiratory Infection on Pediatric Liver Transplant Outcomes.

    J. Kohler,1 T. Miloh,1 K. Hosek,1 J. Goss,2 F. Munoz.1

    1Pediatrics, Baylor College of Medicine, Houston, TX; 2Surgery, Texas Children's Hospital, Houston, TX

    BACKGROUND: Viral upper respiratory infection (vURI) is common in children and its effect at the time of liver transplant (LT) on the post-operative outcomes is…
  • 2017 American Transplant Congress

    Clinical Significance of Alloantibodies in Hand Transplantation: Impact on Rejection and Functional Outcome.

    E. Berglund,1 M. Andersen Ljungdahl,1 D. Bogdanovic,1 D. Berglund,3 J. Wadström,1 A. Weissenbacher,2 P. Petruzzo,4 S. Schneeberger.2

    1Karolinsk Institutet, Dpt of Clinical Science, Intervention, and Technology, Stockholm, Sweden; 2Innsbruck Medical University, Center for Operative Medicine, Innsbruck, Austria; 3Uppsala University, Dpt of Immunology, Genetics and Pathology, Section of Clinical Immunology, Uppsala, Sweden; 4Edouard Herriot Hospital, Dpt of Transplantation, Lyon, France

    Purpose: Although alloantibodies, and donor-specific antibodies (DSA) in particular, are well-known to negatively impact graft survival in human solid organ transplantation, little is known about…
  • 2017 American Transplant Congress

    Circulating Inflammatory Factors in Deceased Organ Donors Result in Innate Immune Activation.

    T. Brennan, L. Lin, J. Pollara.

    Surgery, Duke University, Durham, NC

    Background: Superior outcomes of living-donor compared to deceased-donor transplants may be related to increased graft immunogenicity at the time of transplant. Donor brain death results…
  • 2017 American Transplant Congress

    Outcomes Following Colectomy in Kidney Transplant Recipients.

    S. DiBrito, Y. Alimi, C. Holscher, I. Olorundare, D. Segev, J. Garonzik-Wang.

    Surgery, JHU, Baltimore

    Kidney transplant recipients (KTR), like the general population, often require surgical procedures for non-transplant related issues. Given the need for lifelong immunosuppression and the physiologic…
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