2017 American Transplant Congress
Lymphotoxin (LT) β Receptor-Mediated Non-Classical NFκB Signaling in Lymphatic Endothelial Eells (LEC) is Required for Homeostatic T Cell Migration.
Background: The selective recruitment of regulatory T cells (Treg) or blockade of memory/effector T cell migration to the graft and draining lymph nodes (dLN) are…2017 American Transplant Congress
Graft-versus-Host Disease in Intestine Transplantation.
Surgery, Indiana University School of Medicine, Indianapolis, IN
PurposeThis study reports the incidence, location, and outcomes of graft-versus-host disease (GVHD) at an active intestine transplant center. Subgroup analysis is employed to assess for…2017 American Transplant Congress
CD28 Directed Immunotherapy Is More Potent Than Belatacept in a Nonhuman Primate Xenotransplant Model.
Introduction. Xenotransplantation may alleviate the organ shortage, yet experimental renal xenotransplantation has met limited success. T cell-mediated damage remains a critical problem. Our group has…2017 American Transplant Congress
How to Improve Pre-Kidney Transplant Education for Hispanics: Preferences and Perceptions of Northwestern Memorial Hospital's Hispanic Transplant Program.
Context: Pre-Transplant educational sessions improve access to transplantation. Currently, however, there is lack of culturally competent approaches to improve living kidney donation for Hispanics Americans.…2017 American Transplant Congress
Long-Term Drug-Free Survival of Tiny Cynomolgus Islet Allografts.
Following upon highly beneficial effects observed with short-term alpha 1-antitrypsin (AAT) treatment in the marginally sized autologous cynomolgus islet transplant model, we are testing the…2017 American Transplant Congress
The Combined Effects of Induction Regimens and Antiviral Prophylaxis on the Risk of CMV Infection in Different Serostatus Subgroups After Liver Transplantation.
Introduction: Simultaneous effects of anti-CMV prophylaxis and induction regimens on cytomegalovirus (CMV) infection after liver transplantation (LTRs) have not been studied. We determined the magnitude…2017 American Transplant Congress
TRPV4 Channels Mediate Pulmonary Edema and Inflammation During Ischemia-Reperfusion Injury.
University of Virginia, Charlottesville, VA
Rationale: Lung ischemia-reperfusion (IR) injury remains a major challenge in post-transplant patients. Transient receptor potential vanilloid 4 (TRPV4) cation channels mediate cellular calcium influx, and…2017 American Transplant Congress
Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes (T1D) Post Renal Transplantation.
Introduction: From a risk-benefit perspective, patients with type 1 diabetes (T1D) who are already obligated to long-term immunosuppression to support a kidney transplant and who…2017 American Transplant Congress
Chronic Antibody Mediated Rejection (cABMR) in ABO-Incompatible and ABO-Compatible Kidney Transplants: A Single US Center Experience.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Introduction:Similar patient and graft outcomes have been previously reported for ABO compatible (ABOc) and ABO incompatible (ABOi) kidney transplants. However, data are limited on the…2017 American Transplant Congress
Poor Prediction of Rejection and Kidney Survival by Donor-Specific-Antibodies Characterization.
Kidney transplant recipients with DSA have a greater likelihood of developing antibody-mediated rejection (ABMR) and kidney allograft loss. The aim of this study was to…
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