ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    A Pilot Trial of Genotype-Guided Dosing versus Standard Clinical Dosing in Pediatric Solid Organ Transplants.

    S. Min, T. Daljevic, M. Lafreniere-Roula, C. Manlhiot, N. Nalli, H. Grasemann, S. Schwartz, B. Kamath, V. Ng, R. Parekh, S. Mital.

    The Hospital for Sick Children, Toronto, ON, Canada

    Purpose: Tacrolimus pharmacokinetics are influenced by age and variation in the CYP3A5 gene with CYP3A5 expressors (AA/AG) being fast metabolizers. The purpose of this trial…
  • 2017 American Transplant Congress

    CD40/CD40 Ligand Signal Controls Cytotoxic Ability of Natural Killer Cells After Invariant Natural Killer T Cell Stimulation.

    H. Fukuda,1 T. Hiai,1 R. Ishii,1 H. Katsumata,1 T. Kanzawa,1 S. Miyairi,1 M. Ikemiyagi,1 Y. Ishii,2 M. Okumi,1 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Cluster for Industry Partnerships (CIP), RIKEN IMS-RCAI, Tokyo, Japan

    Because iNKT cells have powerful immune-regulatory function, an administration of iNKT cell ligand; α-galactosylceramide (aGC) is one of the potent strategies for induction of transplant…
  • 2017 American Transplant Congress

    Subpopulations of Peripheral Blood Monocytes in Kidney Allograft Recipients.

    I. Striz,1 V. Svachova,1 A. Sekerkova,1 J. Slatinska,2 K. Kopecka,1 M. Fialova,1 O. Viklicky.2

    1Department of Clinical and Transplant Immunology, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic; 2Department of Nephrology, Transplant Centre, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic

    Human peripheral blood monocytes may be divided into different subsets based on the expression of membrane antigens. Our pilot data suggested that after the kidney…
  • 2017 American Transplant Congress

    Technical Characteristics, Optimization and Outcomes of Ultrasound-Guided Biopsy Performed on Kidney Transplant Patients.

    J. Juega, M. Perez, L. Cañas, M. Troya, I. Bancu, J. Bonet, R. Lauzurica.

    Nephrology Service, Germans Trias i Pujol Hospital, Badalona, Spain

    MATERIAL AND METHODS:From Januray 2014 to August 2016, 183 US-guided renal graft biopsies were performed in our institution.We decided to optimize our biopsy protocol, from…
  • 2017 American Transplant Congress

    Utility of Electron Microscopy in Kidney Transplant Biopsies.

    J. Grodsky,1 R. Craver,1,2 I. Ashoor.2

    1LSUHSC, New Orleans, LA; 2Children's Hospital, New Orleans, LA

    Background: Banff 2013 criteria recommends performing ultra-structural studies with electron microscopy (EM) in most kidney transplant (KT) biopsies if the technology is available. We aimed…
  • 2017 American Transplant Congress

    Variables Associated with Liver Graft Utilization and 30-Day Failure: A Liver Graft Quality Index.

    J. Tang,1 M. Esfandiari,1 A. Zarrinpar.2

    1Statistics, University of California, Los Angeles, CA; 2Surgery, University of California, Los Angeles, CA

    The quantitative evaluation of liver graft quality remains one of the most understudied clinical problems in transplantation. A few scoring systems have been proposed, but…
  • 2017 American Transplant Congress

    WHO Group II Pulmonary Hypertension Is Associated with Decreased Survival in Patients Awaiting Liver Transplantation.

    H. Memon, J.-A. Guerra, B. Trachtenberg, J. Estep, A. Bhimaraj, I. Hussain, M. Park, H. Monsour, M. Ghobrial, A. Guha.

    Medicine, Houston Methodist Hospital, Houston, TX

    End stage liver disease (ESLD) patients with cirrhotic cardiomyopathy often have WHO Group II pulmonary hypertension (PH), characterized by pulmonary capillary wedge pressure (PCWP) >15…
  • 2017 American Transplant Congress

    Utility of Concomitant Biopsy in Simultaneous Pancreas Kidney Transplant Recipients in the Identification of Rejection of Pancreas and Kidney.

    C. Johnson, K. Johnson, B. Kaplan, M. Temkit, R. Heilman, S. Sukumaran Nair, H. Khamash, J. Huskey, G. Mour, H. Chakkera.

    Mayo Clinic Arizona, Phoenix, AZ

    Background: In simultaneous pancreas and kidney transplant (SPKTx) recipients, animal studies suggest concordant rejection rates of 88% (ref: Gruessner et al,1994). Limited information is available…
  • 2017 American Transplant Congress

    Elevated Serum Lipase Levels in Simultaneous Pancreas and Kidney Transplantation May Indicate Anti-HLA Donor Specific Antibody Response.

    B. Javaid, T. Raza, P. Abrams, S. Ghasemian, J. Moore, A. Gilbert, M. Grafals, J. Verbesey, M. Cooper.

    Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC

    Background: Development of anti-HLA donor specific antibodies (DSAs) has been associated with inferior pancreas transplant outcomes. We analyzed data for pancreas and kidney transplant recipients…
  • 2017 American Transplant Congress

    Total Pancreatectomy and Islet Autotransplantation into the Liver of a Patient with Previous Hepatitis C Infection.

    A. Rajab,1 J. Buss,1 P. Hart,2 D. Conwell,2 S. Black,1 K. Washburn.1

    1Transplant Surgery, The Ohio State Wexner Medical Center, Columbus, OH; 2Internal Medicine, The Ohio State Wexner Medical Center, Columbus, OH

    Hepatic parenchymal disease such as hepatitis has been considered a relative contraindication to islet transplantation as the islets are infused into the liver. Islet transplantation…
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