2017 American Transplant Congress
Variability in Tacrolimus Concentrations Across Pediatric Solid Organ Transplants.
PURPOSE: We characterized the evolution of out-of-range tacrolimus (TAC) concentrations and associated factors during 1 year following a pediatric solid organ transplant (SOT).METHODS: Heart, kidney…2017 American Transplant Congress
Distinctive Molecular Features of Antibody-Mediated versus T-Cell Mediated Rejection in Facial Transplantation.
Brigham and Women's Hospital, Boston, MA
BackgroundA single case of antibody-mediated rejection in a clinical face transplant has been reported worldwide. The availability of repeated allograft biopsies from this patient allowed…2017 American Transplant Congress
Thrombalexin and Mirococept Synergistically Reduce IBMIR in a Porcine to Rhesus Xenoislet Model.
Introduction: Early activation of coagulation and complement are important factors in the initiation of instant blood mediated inflammation (IBMIR) in xenoislet models. Two novel 'cytotopic'…2017 American Transplant Congress
Differential Suppressive Effects of Costimulatory Blockade (CD28/B7), Anti-IL6R, Bruton's Tyrosine Kinase and Janus Kinase Inhibition on De Novo vs. Recall Alloantibody Responses: Are Combined Drug Therapy Approaches Desirable?
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Purpose: Preformed and de novo donor specific antibodies (DSA) contribute significantly to demise of allograft functions. There is no approved therapies for prevention or treatment…2017 American Transplant Congress
Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).
Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC
Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…2017 American Transplant Congress
Ethnocultural Barriers to Pre-Emptive Kidney Transplantation: A Single Centre Retrospective Cohort Study.
University Health Network, Toronto, ON, Canada
BackgroundPre-emptive kidney transplant (PKT) may offer better outcomes compared to kidney transplant (KT) after starting dialysis. There is a well-documented disparity in access to PKT…2017 American Transplant Congress
Health Literacy, Functional Status and Transplant Eligibility Among Adult Liver Transplant Candidates.
University of Pennsylvania, Philadelphia; Northwestern University, Chicago
Introduction/Objectives: Low health literacy is associated with poor self-care in chronic diseases, however, is understudied in liver transplantation (LT). Study objectives were to evaluate associations…2017 American Transplant Congress
The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.
Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…2017 American Transplant Congress
In the Modern Era, Cytomegalovirus Does Not Appear to Increase Intimal Thickening After Heart Transplantation.
Cedars-Sinai Heart Institute, Los Angeles
Background: Cytomegalovirus (CMV) has been associated with the subsequent development of cardiac allograft vasculopathy (CAV) after heart transplantation. In the more recent era, CMV has…2017 American Transplant Congress
Severe Tricuspid Regurgitation After Heart Transplantation: Does It Require Surgical Repair?
Cedars-Sinai Heart Institute, Los Angeles
Background: Tricuspid regurgitation (TR) after heart transplantation is common. Causes for TR may be due to volume overload, flail tricuspid leaflet from endomyocardial biopsy, pulmonary…
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