ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Eculizumab Dose Reduction Is Safe by Monitoring Eculizumab Pre-Dose Level and Functional Complement Assays.

    M. Gelens,1 T. Havenith,2 J. Damoiseaux,3 M. Christiaans.1

    1Internal Medicine, MUMC, Maastricht, Netherlands; 2Clinical Pharmacy, MUMC, Maastricht, Netherlands; 3Central Diagnostic Laboratory, MUMC, Maastricht, Netherlands

    Background & aims: Untreated atypical haemolytic syndrome (aHUS) leads to ESRD and may recur after renal transplantation. Eculizumab (Ecu), a humanized antibody inhibiting terminal C5…
  • 2017 American Transplant Congress

    National Variation in US Kidney Transplant Induction Therapy.

    V. Dharnidharka,1 A. Naik,2 T. Alhamad,1 D. Axelrod,3 M. Schnitzler,4,6 Z. Zhang,4 S. Bae,5 D. Brennan,1 D. Segev,5 H. Randall,4 M. Nazzal,4 R. Ouseph,4 B. Kasiske,6 K. Lentine.4

    1Washington Univ, St. Louis, MO; 2U Michigan, Ann Arbor, MI; 3East Carolina Univ, Greenville, NC; 4St. Louis Univ, St. Louis, MO; 5Johns Hopkins, Baltimore, MD; 6Scientific Registry of Transplant Recipients, Minneapolis, MN

    Antibody induction (IND) therapy in kidney transplantation (KTx) reduces acute rejection risk but adds to transplant cost. Currently, only IL2 Receptor antibodies (IL2R-Ab) have FDA…
  • 2017 American Transplant Congress

    Effect of Initial Hepatic Arterial Followed by Portal Reperfusion on Outcomes After Liver Transplantation.

    R. Shahbazov,1 F. Azari,2 J. Alejo,2 M. Talanian,2 M. Fox,2 K. Kennedy,2 S. Kessel,2 A. Nickkholgh,1 D. Maluf,1 S. Pelletier.1

    1Department of Surgery, University of Virginia Medical Center, Charlottesville, VA; 2University of Virginia School of Medicine, Charlottesville, VA

    Background: While initial portal reperfusion (PV) of a liver allograft is nearly standardized, limited data suggests initial hepatic arterial reperfusion (HA) may improve hemodynamics and…
  • 2017 American Transplant Congress

    A Novel Method for Detecting and Monitoring Chimerism in Patients with Graft versus Host Disease After Liver Transplantation.

    B. Peng, H. Liu, K. Cheng, Y. Zhao, X. She, Y. Niu, Q. Zhuang, Y. Ming.

    Transplantation Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Engineering & Technology Research Center for Transplantation Medicine, National Ministry of Health, Changsha, Hunan, China

    Background Graft versus host disease (GVHD) after orthotopic liver transplantation (OLT) is a rare but lethal complication. Early diagnosis and treatment is critical for a…
  • 2017 American Transplant Congress

    The 'W' Technique: A Safe and Reproducible Technique for Hepatic Arterial Reconstruction in Living Donor Liver Transplantation.

    V. Kumaran, V. Varma, S. Kapoor, B. Nath, A. Chauhan, S. Sable, K. Yadav, S. Kumar, S. Sharma.

    Liver Transplant and HPB Surgery, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India

    BackgroundReconstruction of the hepatic artery is technically challenging in living donor liver transplantation (LDLT). We describe outcomes of a safe and easily teachable technique.MethodsA prospectively…
  • 2017 American Transplant Congress

    Age and Race Disparities Among Pediatric and Adult Cystic Fibrosis Lung Transplant Recipients.

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    Pediatric cystic fibrosis (CF) patients have a post-lung transplant survival disadvantage compared to adults. However, whether race and age are risk factors associated with post-transplant…
  • 2017 American Transplant Congress

    Liver Transplantation for Adolescents with Biliary Atresia in the PELD/MELD Era: An Analysis of the UNOS Database.

    J. Chu,1,2 R. Annunziato,3 D. Reinoso,3 A. Ramaswami,2 R. Arnon.1,2

    1Recanati/Miller Transplantation Institute, Mount Sinai Medical Center, New York, NY; 2Pediatrics, Mount Sinai Medical Center, New York, NY; 3Department of Psychology, Fordham University, Bronx, NY

    While poor bile drainage after a Kasai hepatoportoenterostomy (KPE) is the primary driver for liver transplantation (LT) for Biliary Atresia (BA) in infancy, the data…
  • 2017 American Transplant Congress

    Gastrointestinal Perforation After Liver Transplantation in Pediatric Patients.

    M. Kirnap,1 S. Yildirim,1 G. Moray,1 A. Torgay,2 M. Haberal.1

    1General Surgery and Transplantation, Baskent University, Ankara, Turkey; 2Anesthesiology, Baskent University, Ankara, Turkey

    Introduction: The improved surgical techniques, antirejection treatment, and postoperative management have made liver transplantation (LT) the treatment of choice for pediatric patients with end-stage liver…
  • 2017 American Transplant Congress

    Transient High Dose Tacrolimus Allows Tolerance of a Vascularized Composite Allograft Tolerance Across a Full MHC Mismatch.

    A. Leto Barone, H. Wang, E. Swanson, K. Kolegraff, J. Lopez, G. Furtmüller, B. Oh, S. Alfadil, S. Mermulla, J. Sacks, S. Bonawitz, G. Raimondi, J. Shores, D. Cooney, W. Lee, G. Brandacher.

    Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD

    Purpose: The achievement of tolerance in Vascularized composite allografts (VCA) could avoid the risks of immunosuppression in this setting. We investigated strategies for tolerance induction…
  • 2017 American Transplant Congress

    Accelerated De-Novo Donor-Specific Antibody-Mediated Rejection in a Non-Human Primate Model of Renal Transplantation.

    J. Danobeitia, P. Chlebeck, J. Torrealba, T. Zens, L. Zitur, A. D'Alessandro, L. Fernandez.

    Surgery - Division of Transplantation, University of Wisconsin-Madison, Madison, WI

    The development of accelerated antibody-mediated rejection (ABMR) is associated with early allograft dysfunction and premature graft loss. In animals, pre-sensitization is usually required in order…
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