ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Gene Editing of Keap1/Nrf2 in Human T Cells Using CRISPR-Cas9 to Improve Outcome from Ischemia Reperfusion Injury and Other T Cell Mediated Diseases.

    S. Noel,1 S. Lee,1 M. Sadasivam,2 A. Hamad,2 H. Rabb.1

    1Department of Medicine, Johns Hopkins University, Baltimore, MD; 2Department of Pathology, Johns Hopkins University, Baltimore, MD

    Background: T lymphocytes are important mediators of ischemia reperfusion injury (IRI) during organ transplantation. Using genetically engineered mice, we demonstrated that augmentation of Nrf2 dependent…
  • 2017 American Transplant Congress

    Alternations in Amplitude of Low Frequency Fluctuation in Renal Allograft Recipients That Received Tacrolimus or Sirolimus: An fMRI Study.

    J. Wen,1 X. Ni,1 L. Wu,2 G. Zheng,2 L. Zhang,2 J. Chen.1

    1National Clinical Research Center of Kidney Diseases, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; 2Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China

    Objective The side-effects of resting tremor was common in renal transplant receipts receive tacrolimus. But the mechanism of this side-effect was unknown. This study want…
  • 2017 American Transplant Congress

    Immunosuppressant Costs for Medicare Part D and Kidney Transplant Recipients Since the Introduction of Generic Formulations in an Incident Kidney Transplant Population.

    M. Helmuth,1 M. Turenne,1 J. Park,2 Q. Liu,1 M. Oguntimein,3 S. Dutcher,3 R. Balkrishnan,4 J. Zee,1 A. Smith,1 A. Leichtman.1

    1Arbor Research Collaborative for Health, Ann Arbor, MI; 2U of Michigan, Ann Arbor, MI; 3Food and Drug Administration, Silver Spring, MD; 4U of Virginia, Charlottesville, VA

    Background: Substitution of generics (GEN) for brand name (BN) immunosuppressants (IS) has increased in kidney transplant recipients (KTR) since the introduction of GEN mycophenolate mofetil…
  • 2017 American Transplant Congress

    Long-Term Persistence of Anti-HLA Antibodies in Renal Trasplant Recipients: Risk Factors and Impact on Clinical Course.

    I. Perez-Flores,1 J. Santiago,2 B. Rodriguez-Cubillo,1 M. Moreno De La Higuera,1 V. Lopez De La Manzanara,1 J. Bautista-Cañas,1 N. Calvo Romero,1 A. Shabaka,1 E. Urcelay,2 A. Sanchez-Fructuoso.1

    1Nephrology, Hospital Clínico San Carlos, Madrid, Spain; 2UGC Immunology, Hospital Clínico San Carlos and Instituto de Investigación Sanitaria (IdISSC), Madrid, Spain

    Objectives:1) To evaluate the incidence of development of anti-HLA antibodies on the long run in our renal transplant population and the main risk factors for…
  • 2017 American Transplant Congress

    Clinical Outcomes of Kidney Transplant Recipients by Steroid Early Withdraw Protocol with Basiliximab Induction.

    Y. Takada, K. Hotta, D. Iwami, H. Higuchi, T. Hirose, H. Sasaki, N. Shinohara.

    Urology, Hokkaido University Hospital, Sapporo, Japan

    [Purpose] Several steroid early withdrawal protocols (SEWD) have been attempted in recent decades to avoid steroid related adverse effects among kidney transplant recipients. However, there…
  • 2017 American Transplant Congress

    Combined Endoscopic and Percutaneous Cholangiography for Biliary Anastomotic Stricture in Adult Right-Lobe Living-Donor Liver Transplantation.

    A. Thorat,1 W.-H. Huang,2 C.-J. Yu,2 C.-Y. Peng,2 H.-R. Yang,1 C.-C. Yeh,1 T.-H. Chen,1 S.-C. Hsu,1 L.-B. Jeng.1

    1Organ Transplantation, China Medical University Hospital, Taichung, Taiwan; 2Internal Medicine, China Medical University Hospital, Taichung, Taiwan

    Background:Biliary anastomotic stricture isthe most common biliary complication after living donor liver transplantation (LDLT) that may be potentially life threatening if biliary sepsis occurs.Endoscopic retrograde…
  • 2017 American Transplant Congress

    Prolonged Cold Ischemia Time as a Risk for Low Regeneration at the Early Phase After Living Donor Liver Transplantation.

    K. Takahashi,1,2 S. Nagai,1 M. Safwan,1 K. Putchakayala,1 M. Rizzari,1 K. Collins,1 A. Yoshida,1 G. Schnickel,1 M. Abouljoud.1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 2Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan

    Background. The objective of this study was to determine the risk factors for low liver regeneration at the early phase after living donor liver transplantation…
  • 2017 American Transplant Congress

    The Impact of Insurance Status on Waiting List and Post-Lung Transplant Survival in Patients with Cystic Fibrosis.

    C. Lehr,1 M. Skeans,2 E. Dasenbrook,1 M. Valapour.1,2

    1Cleveland Clinic, Cleveland, OH; 2Scientific Reg of Transplant Recipients, Minneapolis, MN

    Studies show that insurance status at the time of wait-listing affects waitlist and posttransplant survival after lung transplant. No studies have analyzed the effect of…
  • 2017 American Transplant Congress

    The Impact of Scleroderma Diagnosis on Lung Transplant Outcomes: A Single Center's Experience.

    H. Memon, A. Frost, E. Graviss, D. Nguyen, A. Goodarzi, N. Sinha.

    Medicine, Weill Cornell Medical College, Houston Methodist Hospital, Houston, TX

    Patients with scleroderma (SSC) associated restrictive lung disease (RD) and pulmonary hypertension (PH) are often turned down for lung transplant due to associated co-morbidities, particularly…
  • 2017 American Transplant Congress

    Comparing Outcomes Between Technical Variant Liver Allografts and Whole Allografts in Pediatric Liver Transplantation: A Single Center's Experience.

    A. Gallo,1 J. Lee,1 M. Damian,2 D. Stoltz,1 C. Bonham,1 C. Esquivel,1 J. Mendoza.3

    1Surgery, Stanford University, Palo Alto, CA; 2Intensive Care, Stanford University, Palo Alto, CA; 3Anesthesia, Stanford University, Palo Alto, CA

    Objective: To compare the outcome of technical variant liver transplants to whole allograft liver transplants in pediatric recipients.Methods: A single center retrospective analysis of outcomes…
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