Am J Transplant, Volume 17, Suppl 3 Archives - Page 114 of 181 - ATC Abstracts

2017 American Transplant Congress
ECMO in Liver Transplant.
N. Goussous,^1,2 S. Hanish,¹ J. LaMattina,¹ Z. Kon,¹ D. Potosky,¹ J. Scalea,¹ W. Hutson,¹ R. Barth,¹ D. Bruno.¹
¹University of Maryland, Baltimore, MD; ²Saint Agnes Hospital, Baltimore, MD
Introduction: Postoperative severe cardiopulmonary failure carries a high rate of mortality. Extracorporeal membrane oxygenation (ECMO) has been used as a salvage therapy when conventional therapies…
2017 American Transplant Congress
Posttransplant Employment Patterns Are More Favorable in Patients with Solitary Pancreas vs. Simultaneous Pancreas/Kidney (SPK) Transplants – The Impact of Native Kidney Function.
S. Gruessner.
SUNY Upstate Medical University, Syracuse
Introduction: Insulin-dependent diabetes mellitus (DM) is a debilitating disease resulting in life-limiting secondary complications. A successful pancreas (Pa) transplant (Tx) achieves normoglycemia, extends life expectancy…
2017 American Transplant Congress
Impact of Pancreatic Texture Assessment on Islet Isolation and Metabolic Outcome After TPIAT.
G. Yoshimatsu,¹ M. Khadka,¹ M. Lawrence,¹ B. Appakalai,² B. Naziruddin.³
¹Baylor Scott and White Research Institute, Dallas, TX; ²University of Louisville, Louisville, KY; ³Baylor Simmons Transplant Institute, Dallas, TX
Introduction: Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment for refractory chronic pancreatitis (CP). Chronic inflammation leads to fibrosis formation in pancreas and…
2017 American Transplant Congress
Pilot Study on Acupuncture in Living Liver and Kidney Donors.
M. Jesse, M. Kulas, J. Unitis, N. Beltran, M. Abouljoud.
Transplant Institute, Henry Ford Health System, Detroit
Pain is an important concern in living donation. The purpose of this study was to test feasibility of integrating an acupuncture intervention pre/post-living donation and…
2017 American Transplant Congress
Operational Tolerance in Intestinal Transplantation: A Proven Possibility.
B. Houlihan,¹ P. Cha,^1,2 C. Cosentino,^1,2 J. Kaiser,^1,2 A. Shukla,¹ J. Hawksworth,^1,2 C. Matsumoto,¹ T. Fishbein,¹ A. Kroemer.¹
¹Transplant Department, Medstar Georgetown University Hospital, Washington, DC; ²Surgery, Walter Reed National Military Medical Center, Bethesda, MD
A The purpose of this study is to immunologically characterize the first operationally tolerant intestinal transplant (ITx) patient known to date.B Flow cytometry and rtPCR…
2017 American Transplant Congress
Preventing Alloimmune Rejection in Heart Transplantation by Tolerogenic Dendritic Cells Induced by GDF15 Through Up-Regulation of IDO and Inhibition of the NFκB Signalling Pathway.
Y. Zhang,^1,3 G. Zhang,¹ L. Moszczynski,¹ D. Zhao,^1,3 P. Abulizi,¹ D. Quan,² T. Mele,² K. Liu,³ X. Zheng.^1,2
¹Pathology, University of Western Ontario, London, ON, Canada; ²Surgery, University of Western Ontario, London, ON, Canada; ³Cardiovascular Surgery, Jilin University, Cahngchun, China
Rationale: Growth differentiation factor 15 (GDF15) can inhibit DC maturation, yet whether it can generate tolerogenic dendritic cells (Tol-DCs) to induce immune tolerance in heart…
2017 American Transplant Congress
CD8+ TAb-supp Cells Are Key Inhibitors of Humoral Alloimmunity by Inhibiting CD4+TFH Cells and Killing Germinal Center B Cells.
J. Zimmerer, C. Avila, S. Elzein, B. Ringwald, R. Warren, G. Bumgardner.
Surgery, The Ohio State University Wexner Medical Center, Columbus, OH
Alloantibodies (alloAb) play a critical role in acute and chronic rejection after transplantation (Tx). It is well known that CD4+ T cells and B cells…
2017 American Transplant Congress
Depletion of T-Cells from G-CSF Mobilized Human PBMC Prevents Acute GVHD in NSG Mice.
Y. Huang, H. Xu, A. Merchak, A. Chhabra, Y. Wen, L. Kahn, S. Ildstad.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY
Allogeneic HSC transplantation is commonly utilized for the treatment of hematologic malignancies and autoimmune diseases. However, allogeneic HSC transplantation is limited by potential for the…
2017 American Transplant Congress
Donor-Derived Cell-Free DNA Parallels Increases in Donor Specific Antibodies in Pediatric Kidney Transplant Recipients.
D. Stoltz,¹ A. Brubaker,¹ M. Grskovic,² R. Woodward,² A. Gallo.¹
¹Surgery, Stanford University, Palo Alto, CA; ²CareDx, Brisbane, CA
Introduction: Anti-HLA antibody screening is a critical component of post-kidney transplant surveillance. Existing protocols and treatment plans are not standard/consistent across institutions. As increasing numbers…
2017 American Transplant Congress
Omega 3 Attenuates Ischemia Reperfusion Renal Injury via Enhancement of Autophagy Flux.
J.-J. Kim,¹ J. Jeong,² D. Choi,³ K. Na,³ K. Lee.³
¹Chungnam National University, Anatomy, Daejeon, Korea; ²Chungnam National University, Department of Medical Science, Daejeon, Korea; ³Chungnam National University, Nephrology, Daejeon, Korea
Purpose: Omega 3 fatty acid showed the protective effect against various renal injuries. Recently, it is reported that Omega 3 regulates the autophagy. Using fat-1…