ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Risk Factors for Polyomavirus Infection After Renal Transplantation: Introduction of the Protective Effect of Peritoneal Dialysis.

    S. Hosseini-Moghaddam, Q. Xu, J. Kum, H. Alharbi, A. Jevnikar, M. John, G. Singh, S. Parsons, M. Edgar, P. Luke.

    Medicine, Western University, London Health Sciences Centre, London, ON, Canada

    Objective: To determine the roles of pre and post-transplant variables on the risk of BK virus infection after renal transplantation.Method: This study is a single-…
  • 2017 American Transplant Congress

    Measles Screening and Vaccination in Solid Organ Transplant Recipients: Adherence to Infectious Disease Community of Practice (IDCOP) Recommendations.

    F. Irani,1 R. Butler,2 C. Kovacs.

    1Infectious Disease, Cleveland Clinic, Cleveland; 2Statistics, Cleveland Clinic, Cleveland

    Background: Measles is a highly contagious viral infection that rarely affects transplant recipients. Cases remain in the United States due to vaccine refusal and importation…
  • 2017 American Transplant Congress

    Immune Activation and Rejection Risk in HIV-Positive Kidney Transplantation.

    S. Wisel, B. Shaw, L. Lee, K. Lee, C. Leung, P. Stock, Q. Tang.

    Division of Transplantation, University of California, San Francisco, San Francisco, CA

    Purpose: HIV+ kidney transplant recipients experience higher rates of rejection episodes when compared to HIV- recipients. We hypothesize that this early, aggressive rejection is associated…
  • 2017 American Transplant Congress

    Vimentin Regulates ß-Catenin Translocation During Epithelial to Mesenchymal Transition in Renal Fibrosis.

    R. Lopez-Soler, Z. Wang, A. Divanyan.

    Sugery, Section of Transplantation, Albany Medical Center, Albany, NY

    Introduction: Most renal transplants ultimately fail secondary to chronic allograft nephropathy (CAN). The development of Epithelial to Mesenchymal Transition (EMT) in renal tubular epithelial cells…
  • 2017 American Transplant Congress

    Vascularized Bone Marrow Mechanisms of Immunomodulation.

    A. Khalifeh, E. Buckingham, M. Uluer, W. Hassanein, W. Twaddell, C. Drachenberg, A. Nam, S. Bartlett, R. Barth.

    University of Maryland School of Medicine, Baltimore, MD

    Introduction:Hand and face transplants containing co-transplanted bone may have improved outcomes. We have previously utilized a NHP model to demonstrate that VCA containing VBM have…
  • 2017 American Transplant Congress

    Molecular Significance of Peritubular Capillaritis in Early Transplant Kidney Biopsies of Donor-Specific Antibody Negative Patients.

    M. Ajaimy, P. O Broin, Y. Bao, E. Akalin.

    Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, Bronx

    Background: Peritubular capillaritis (PTC) is a part of microvascular inflammation seen in antibody-mediated rejection. However, it can be observed as an isolated lesion in early…
  • 2017 American Transplant Congress

    Preformed HLA Donor-Specific Antibodies Disappearance After Kidney Transplantation: Significance and Comparison with Persistent DSA.

    D. Redondo,1 M. Pérez-Sáez,1 M. Mir,1 J. Gimeno,1 C. García,2 J. Hernández,2 J. Yélamos,3 J. Pascual,1 M. Crespo.1

    1Nephrology Department, Hospital del Mar, Barcelona, Spain; 2Laboratori de Referència de Catalunya, Barcelona, Spain; 3IMIM, Barcelona, Spain

    The presence of donor-specific antibodies (DSA) increase the risk of antibody-mediated rejection (ABMR) and graft failure in kidney transplant recipients (KTR). We aimed to analyze…
  • 2017 American Transplant Congress

    Outcomes of Recurrent Clostridium difficile Infection in Solid Organ Transplant Recipients.

    M. Shiotsuka, Y. Natori, D. Kumar, A. Humar, C. Rotstein, S. Husain.

    Transplant Infectious Diseases, University Health Network, Toronto, ON, Canada

    Introduction:Clostridium difficile infection(CDI) is one of the leading infectious causes among solid organ transplant (SOT) recipients. While the recurrence rate is relatively high, clinical outcomes…
  • 2017 American Transplant Congress

    Identifying Risks and Screening Deceased Organ Donors in the UK for Trypanosoma cruzi .

    I. Ushiro-Lumb,1,2 M. Webster,1 A. Kitchen.1

    1Microbiology Services, NHS Blood and Transplant, London, United Kingdom; 2Virus Reference Department, Public Health England, London, United Kingdom

    Background: In the UK, the Advisory Committee on Microbiological Safety of Blood, Tissues and Organs recommends discretionary T. cruzi antibody screening of donors with identified…
  • 2017 American Transplant Congress

    Dual Role for Caspase-3 in the Regulation of Tubular and Microvascular Damage Post-Renal Ischemia-Reperfusion Injury.

    B. Yang,1,2,3 S. Lan,1,2,3 N. Patey,1,3,4 J. Turgeon,1,3 M. Dieudé,1,3 M.-J. Hébert.1,2,3

    1Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada; 2Canadian National Transplant Research Program, Edmonton, AB, Canada; 3Université de Montréal, Montreal, QC, Canada; 4Department of Pathology, CHU Ste-Justine, Université de Montréal, Montreal, QC, Canada

    Ischemia-reperfusion injury (IRI) in renal transplant recipients is a risk factor of allograft dysfunction and reduced survival. Although tubular epithelial cells (TEC) are classically considered…
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