ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Metabolic Recovery and Ex Vivo Simulation of Early Liver Reperfusion.

    B. Bruinsma,1 J. Avruch,2 G. Sridharan,1 P. Weeder,1 N. Karimian,1 J. Markmann,2 K. Uygun,1 H. Yeh.2

    1Center for Engineering in Medicine, Massachusetts General Hospital, Boston, MA; 2Transplant Center, Massachusetts General Hospital, Boston, MA.

    Purpose. An urgent need for more liver grafts for transplantation has prompted the use of more suboptimal organs. Particularly in these more marginal livers adequate…
  • 2016 American Transplant Congress

    Genomic-Derived Markers to Identify Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.

    E. Rhone,1 R. Gehrau,2 S. Bontha,2 P. Walker,3 C. Dumur,4 D. Maluf,2 V. Mas.2

    1Pediatrics, University of Virginia, Charlottesville, VA; 2Surgery, University of Virginia, Charlottesville, VA; 3Nephropath, Little Rock, AR; 4Pathology, Virginia Commonwealth University, Richmond, VA.

    Background:Calcineurin inhibitor nephrotoxicity (CNIT) is a well-known contributor to chronic allograft dysfunction in kidney transplant recipients (KTRs). Pediatric KTRs are particularly at risk given their…
  • 2016 American Transplant Congress

    Alemtuzumab Is Safe and Effective Induction Therapy in Highly Sensitized (HS) Pediatric Patients Undergoing Transplantation.

    I. Kim,1 J. Choi,1 A. Vo,1 A. Kang,1 M. Toyoda,1 J. Mirocha,2 E. Kamil,1 S. Louie,1 O. Galera,1 S. Jordan,1 D. Puliyanda.1

    1Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; 2Biostatistics Core, Cedars-Sinai Medical Center, Los Angeles, CA.

    Introduction: Studies show that alemtuzumab, a potent lymphocyte-depleting agent, is well-tolerated in pediatric renal transplantation. We report on the use of alemtuzumab induction in HS…
  • 2016 American Transplant Congress

    Effect of Donor-Recipient Gender Mismatch in Liver Transplant Recipients: A Post-Hoc Analysis of the H2304 Study.

    L. Fischer, P. de Simone, G. Dong, P. Lopez, P. Bernhardt, F. Saliba.

    H2304 study group, Hamburg, Germany.

    Purpose: Donor-recipient gender mismatch may play a role in liver transplant (LTx) outcomes. Here we present the 24-month results from the post-hoc analysis of the…
  • 2016 American Transplant Congress

    Here Comes the Sun: Industry's Payments to Transplant Physicians.

    R. Ahmed,1 E. Chow,2 S. Bae,2 A. Massie,2 E. King,2 B. Orandi,2 J. Lopez,2 B. Lonze,2 D. Segev.2

    1Plastics and Reconstructive Surgery, Duke University Medical Center, Durham, NC; 2General Surgery, Johns Hopkins School of Medicine, Baltimore, MD.

    Background: The Open Payments Program (OPP) was implemented to publicly disclose industry payments to physicians, enabling patients to be aware of conflicts of interests. We…
  • 2016 American Transplant Congress

    Children Listed as Status 1B for Liver Transplantation Are Disenfranchised by MARS Therapy.

    A. Bakshi,1 M. Kueht,1 A. Rana,1,2 A. Akcan Arikan,3 J. Goss.1,2

    1Surgery, Division of Abdominal Transplantation and Hepatobiliry Surgery, Baylor College of Medicine, Houston, TX; 2Surgery, Division of Abdominal Transplantation, Texas Children's Hospital, Houston, TX; 3Pediatric Medicine, Intensive Care, Texas Children's Hospital, Houston, TX.

    Acute exacerbations of chronic liver failure in the pediatric population require advanced ICU care in order to survive to transplantation (OLT). Often, the patients are…
  • 2016 American Transplant Congress

    Growth of Liver Allografts in Pediatric Transplant Recipients.

    S. Chaudhry, J. Stern, S. Lobritto, M. Martinez, J. Vitorrio, J. Emond, T. Kato, B. Samstein, S. Bentley-Hibbert, A. Griesemer.

    Columbia University Medical Center, New York, NY.

    IntroductionThe liver's capacity to grow in response to metabolic need is well known. However, the long-term growth of liver allografts transplanted in pediatric patients has…
  • 2016 American Transplant Congress

    Incidence of Polyoma Virus Associated Nephropathy in a Single Transplant Center Employing a Reduction of Immunosuppression at a Lower Threshold of BK Viremia.

    M. Azar, A. Valika, D. Banach, I. Hall, M. Malinis.

    Internal Medicine, Infectious Diseases, Yale University, New Haven, CT.

    BackgroundPolyoma virus associated nephropathy (PyVAN) caused by BK virus (BKV) is a major complication occurring in 1-10% of renal transplant recipients. Screening and reduction of…
  • 2016 American Transplant Congress

    Urinary Tract Infections During the First Year After Renal Transplantation: Risk Factors and Nomograms.

    C. Jironda, V. López, M. Cabello, A. Duarte, C. Gutiérrez, P. Ruiz, D. Burgos, D. Hernández.

    Nephrology, Regional University Hospital, Málaga, Spain.

    Background: Urinary tracts infections (UTIs) are the most common infectious complications following renal transplantation (RT). The aim of this study was to evaluate the frequency…
  • 2016 American Transplant Congress

    Marked Alterations in Gene Expression in Peripheral Blood Leukocytes of Kidney Transplant (tx) Recipients Following Mycophenolic Acid (MPA) Treatment.

    K. Sanghavi,1 B. Wu,1 C. Dorr,2 A. Muthuswamy,2 W. Guan,1 D. Schladt,2 R. Remmel,1 D. Ilke,3 A. Matas,1 A. Israni,2 W. Oetting,1 P. Jacobson.1

    1University of Minnestoa, Minneapolis; 2MMRC, Hennepin County Medical Center, Minneapolis; 3Rho.

    MPA exerts its immunosuppressive activity by inhibiting IMPDH2 enzyme, halting DNA synthesis in T and B lymphocytes. Cell culture models have shown MPA effects on…
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