2016 American Transplant Congress
Differences in Tacrolimus Troughs and Doses Between Caucasians and African Americans with Two CYP3A5 Loss-of-Function Alleles: Looking Beyond CYP3A5 Expression.
Higher tacrolimus (TAC) dose requirements and lower TAC troughs (TT) in African Americans (AA) relative to Caucasians (CA) have been presumed to be due to…2016 American Transplant Congress
Changes in Fatigue After Kidney Transplantation.
Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Previous research suggests that 60 to 97% of patients on dialysis experience fatigue, or a feeling of persistent tiredness or exhaustion. ESRD patients with fatigue…2016 American Transplant Congress
Reduced-Dose Cidofovir (CID) and CMV-Hyperimmune Globulin (CMVIg) for Ganciclovir-Resistant Cytomegalovirus: Effective and Kidney Friendly.
Houston Methodist Hospital, Houston, TX.
Ganciclovir resistant (GR) CMV is associated with an aggressive disease course and substantial morbidity. Furthermore, treatment options such as foscarnet and cidofovir are incredibly nephrotoxic.…2016 American Transplant Congress
Characteristics of Human Rhinovirus (HRV) Infections in Transplant Recipients.
Introduction:Although HRV is a common cause of benign upper respiratory infection, there are reports of HRV resulting in lower respiratory tract infection (LRTI) in HSCT…2016 American Transplant Congress
Focal C4d Staining in Biopsies of Kidney Transplant Recipients Is Not Associated with Antibody Mediated Rejection and Does Not Correlate with Graft Survival.
Transplant Institute, Henry Ford Hospital, Detroit, MI.
Introduction: While diffuse C4d positivity in kidney transplant peritubular capillaries(PTC) strongly co-relates with the presence of antibody mediated rejection(AMR),data on the significance of focal C4d…2016 American Transplant Congress
The Early Outcomes of Bortezomib Therapy in Patients with Late Antibody Mediated Rejection in Renal Transplantation.
Although several strategies for treating antibody mediated rejection (AMR) in renal transplants have been investigated, the formation of donor-specific antibodies (DSA) and ongoing AMR contribute…2016 American Transplant Congress
The Therapeutic Potential of Human Liver-Derived Stem Cell Transplantation in a Cirrhotic Liver Rat Model.
Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Previous studies suggested that MSCs may ameliorate fibrogenesis through…2016 American Transplant Congress
IgM Treatment Successfully Prevents Type 1 Diabetes by Dysregulation of Pancreatic MicroRNAs with Immunomodulatory Roles.
Type 1 Diabetes (T1D) is hallmarked by beta-cells destruction. We aimed to identify specific pancreatic microRNAs (miRNA) as potential biomarkers for T1D prediction and diagnosis,…2016 American Transplant Congress
Chemokine Receptor CXCR4 Antagonist, a Novel Pathway to Prevent Chronic Allograft Nephropathy.
Department of Urology, Beijing Chaoyang Hospital, Beijing, China.
BackgroundChronic allograft nephropathy (CAN) remains a major problem for long term graft survival and different pathways participate in its development. CXC chemokine receptor 4 (CXCR4)…2016 American Transplant Congress
Memory Regulatory T Cell: A Potential Actor in Immunological Operational Tolerance in Kidney-Transplant Patients via the ATP Degradation into Adenosine.
Regulatory T cells (Tregs) are essential actors in the control of self-tolerance and exacerbated inflammation. In experimental transplantation Tregs are critical to achieve alloantigen tolerance…
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