ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Predicting Early Cardiac Death After Kidney Transplantation.

    K. Balabhadrapatruni, A. Liu, N. Sarabu, E. Sanchez, J. Augustine.

    Medicine, University Hospitals Case Medical Center, Cleveland, OH.

    Background: Early cardiac mortality is a devastating occurrence after transplantation. We sought to analyze risk factors and patient characteristics, including the estimated post transplant survival…
  • 2016 American Transplant Congress

    Circulating Soluble-Klotho Levels Modestly Increase After Renal Transplantation.

    S.-J. Tan,1 A. Crosthwaite,2 D. Langsford,3 V. Obeysekere,4 F. Ierino,2,5 M. Roberts,5,6 S. Holt,1 T. Hewitson,1 K. Dwyer,3,5,7 N. Toussaint.1

    1Dept of Nephrology, The Royal Melbourne Hospital, Melbourne, Australia; 2Dept of Nephrology, Austin Hospital, Heidelberg, Victoria, Australia; 3Dept of Nephrology, St Vincent's Hospital, Melbourne, Australia; 4Dept of Endocrinology, St Vincent's Hospital, Melbourne, Australia; 5Victorian Kidney Transplantation Collaborative, Melbourne, Australia; 6Dept of Renal Medicine, Eastern Health, Box Hill, Australia; 7School of Medicine, Deakin University, Geelong, Australia.

    Background: Klotho, a co-receptor for FGF23, is predominantly expressed in kidney and reported to have anti-oxidant and anti-fibrotic properties. Soluble-Klotho (sKl), the cleaved circulating protein,…
  • 2016 American Transplant Congress

    Pre-Mortem Cannulation and NECMO Preservation for DCD Liver Transplantation.

    P. Ruiz,1 M. Gastaca,1 A. Valdivieso,1 A. Ventoso,1 I. Palomares,1 M. Prieto,1 J. Bustamante,2 P. Salvador,2 J. Ortiz de Urbina.1

    1Liver Surgery and Liver Transplant Unit, Cruces University Hospital, Bilbao, Vizcaya, Spain; 2Hepatology and Liver Transplant Unit, Cruces University Hospital, Bilbao, Vizcaya, Spain.

    Introduction: Herein, we present the short-term results of a controlled DCD liver transplantation program with pre-mortem cannulation and normothermic extracorporeal membrane oxygenation (NECMO) preservation.Material and…
  • 2016 American Transplant Congress

    Increased Utilization of High Risk Deceased Donors with Share 35 Does Not Affect Outcomes in Liver Transplantation.

    M. Boktour, A. Saharia, D. Victor, S. Gordon-Burroughs, C. Mobley, R. McFadden, V. Ankoma-Sey, J. Galati, A. Gaber, H. Monsour, R. Ghobrial.

    Sherrie and Alan Conover Center for Liver Disease and Transplantation, Houston Methodist Hospital, Houston, TX.

    Background: Demand for livers from deceased donors exceeds supply after Share 35 in June 2013. This leads liver transplant centers to consider high risk deceased…
  • 2016 American Transplant Congress

    Outcomes in Lung Transplant Patients Requiring Extracorporeal Membrane Oxygenation (ECMO) in the Perioperative Period.

    A. Habertheuer, M. Williams, S. Miller, E. Cantu, C. Bermudez, P. Vallabhajosyula.

    Cardiovascular Surger, Hospital of the University of Pennsylvania, Philadelphia, PA.

    Objective As ECMO therapy is increasingly used to bridge high-risk patients with end-stage respiratory failure to lung transplantation, outcomes of this strategy employed in the…
  • 2016 American Transplant Congress

    C3 Glomerulopathy Secondary to Complement Factor H Inhibition by Monoclonal Kappa Light Chains.

    C. Blosser,1 Y. Zhang,2 T. Dhawale,3 C. Johnson,1 P. Hendrie,3 R. Smith.2

    1Medicine, University of Washington, Seattle, WA; 2Medicine & Surgery, University of Iowa, Iowa City, IA; 3Medicine, Seattle Cancer Care Alliance, Seattle, WA.

    Background: Monoclonal gammopathy of renal significance (MGRS) implies a causal relationship between clonal B cell proliferation and renal disease and is associated with high morbidity…
  • 2016 American Transplant Congress

    Anti-HLA Antibodies in Allogeneic and Autologous Hematopoietic Stem Cell Transplantation.

    A. Bertocchi, L. Requiao-Moura, M. Torres, E. Tonato, M. Durao Junior, A. de Matos, N. Hamershclak, A. Pacheco-Silva.

    Kidney Transplantation, Hematology, Histocompatibility Laboratory, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

    Introduction: Anti-HLA antibodies have been associated with graft rejection in solid organ and hematopoietic stem cell transplantation (HSCT). The aim of this study was describe…
  • 2016 American Transplant Congress

    Association of Genetic Polymorphisms in Complement Independent Pathways with Donor Specific Antibodies in Kidney Allograft Recipients.

    Y. Chang,1,2 T. Shah,1,3 D. Min.1

    1Western University of Health Sciences, Pomona, CA; 2Mendez National Institute of Transplantation Foundation, Los Angeles, CA; 3St. Vincent Medical Center, Los Angeles, CA.

    Background: It is known that detection of donor specific antibodies (DSA) is associated with antibody mediated rejection (AMR) and poor allograft outcomes. DSA mediates graft…
  • 2016 American Transplant Congress

    Safety, Efficacy, and Cost Saving Potential of Various Weight-Based Dosing for Thymoglobulin Induction Therapy in Kidney Transplant Recipients.

    R. Miller,1 H. Meadows,1 S. Strout,1 T. Veasey,1 A. Mardis,1 J. Fleming,1 C. Mardis,1 N. Pilch,1 K. Chavin,2 D. Taber.2

    1Department of Pharmacy, Medical University of South Carolina, Charleston, SC; 2Department of Surgery, Medical University of South Carolina, Charleston, SC.

    Introduction: There are limited data assessing the appropriate weight to use when dosing Thymoglobulin for induction therapy. The aim of this study is to assess…
  • 2016 American Transplant Congress

    Virtual Crossmatching Under the New KAS: Safely Bypassing a Physical Crossmatch When Allocating Kidneys to Highly Sensitized Candidates.

    R. Bray,1 R. Parsons,2 N. Turgeon,2 H. Gebel.1

    1Pathology, Emory University, Atlanta, GA; 2Emory Transplant Center, Emory University, Atlanta, GA.

    AIM: On 12/4/2014, the OPTN implemented a new KAS for deceased donor(DD) transplants which, among many changes, increased priority for highly sensitized (HS) candidates (cPRA>98%).…
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