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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Preoperative Cytokine Storm in High MELD Patients Accentuates Incidence of Rejection Following Liver Transplantation.

    A. Mathur, E. Presbyskowski, E. Zorn, K. Rogers, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, T. Kato, J. Emond.

    Abdominal Transplant Surgery, Columbia University, NY, NY.

    IntroductionAcute Cellular Rejection (ACR) affects 30 percent of all liver transplants. Histologically it is characterized by cellular inflammation in the veins, bile ducts and portal…
  • 2016 American Transplant Congress

    A Model to Explore the Potential Budget Impact of a Novel Screening Tool for the Detection of Subclinical Rejection Among Kidney Transplant Patients.

    K. Jaglinski,1 H. Uchida,1 T. Inocencio,2 K. Hughes.2

    1Immucor, Inc, Waukesha, WI; 2Avalare Health, LLC, Washington, DC.

    Background: Acute rejection among kidney transplant patients is common, with ~10% of individuals experiencing acute rejection within the first year and rising to 16-17% at…
  • 2016 American Transplant Congress

    Use of En-Bloc Vascularized Rectus Sheath Allograft to Achieve Abdominal Closure in Pediatric Liver and Multivisceral Transplantation.

    J. Reddy, A. Rege, D. Vikraman, B. Collins, T. Brennan, S. Knechtle, D. Sudan, K. Ravindra.

    Surgery, Duke University, Durham, NC.

    Background: Abdominal wall closure is often challenging in pediatric liver (LT) and multivisceral transplantation (MVT) due to size discrepancy of donor & recipient and abdominal…
  • 2016 American Transplant Congress

    Biopsy-Proven Rejection in Children After Liver Transplantation Is Associated by an IL-12p40-Mediated Innate Immune Response Followed by Th1 T Cell Activation.

    C. Falk,1 I. Goldschmidt,2 F. Mutschler,2 E. Pfister,2 F. Lehner,3 J. Keil,1 C. Neudörfl,1 A. Karch,4 R. Mikolajczyk,4 U. Baumann.2

    1Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Bitte Wählen, Germany; 2Department of Pediatric Hepatology, Hannover Medical School, Hannover, Bitte Wählen, Germany; 3Department of Abdominal and Transplantation Surgery, Hannover Medical School, Hannover, Bitte Wählen, Germany; 4Department of Epidemiology, Helmholtz Center for Infection Research, HZI, Braunschweig, Germany.

    Sustained by adaptive immune cells and their soluble mediators is well established for infection but it has not been demonstrated for solid organ transplantation in…
  • 2016 American Transplant Congress

    Factors Associated with Response to Plasmapheresis in Patients with Recurrent FSGS.

    J. Shoji,1 V. Tatapudi,2 Z. Laszik,1 A. Jones,3 J. Wolf,4 D. Adey,1 F. Vincenti.1

    1Department of Medicine, Division of Nephrology, University of California-San Francisco, California, CA; 2Department of Medicine, Division of Nephrology, New York University, New York, NY; 3Department of Sociology, George Washington University, Washington, DC; 4Transplant Surgery, Piedmont Transplant Institute, Atlanta, GA.

    Background:Idiopathic focal segmental glomerulosclerosis (FSGS) is one of the primary glomerular diseases that commonly recurs in renal allograft and is known to be associated with…
  • 2016 American Transplant Congress

    Risk of Peritoneal Dialysis Catheter-Associated Peritonitis Following Kidney Transplant.

    A. Rizzi,1 S. Ruitta,1 J. Peterson,1 G. Gagin,1 D. Fritze,1 R. Sung,1 Y. Lu,2 K. Woodside.1

    1Department of Surgery, University of Michigan, Ann Arbor, MI; 2Department of Internal Medicine, University of Michigan, Ann Arbor, MI.

    While peritoneal dialysis (PD) has become more common, PD catheter management at the time of kidney transplant varies widely by transplant center. We sought to…
  • 2016 American Transplant Congress

    Concomitant Proton Pump Inhibitor and Mycophenolate Mofetil Use in Renal Transplant Recipients.

    K. Patel,1 B. Stephany,2 J. Barnes,1 S. Bauer,1 M. Spinner.1

    1Department of Pharmacy, Cleveland Clinic, Cleveland, OH; 2Department of Nephrology and Hypertension, Cleveland Clinic, Cleveland, OH.

    Pharmacokinetic (PK) data show reduced mycophenolic acid levels in transplant recipients taking mycophenolate mofetil (MMF) and proton pump inhibitors (PPIs) concomitantly. MMF dosing is not…
  • 2016 American Transplant Congress

    American and European Transplant Surgeons: Research, Teaching, and Burnout.

    M. Jesse,1 M. Abouljoud,1 A. Eshelman,1 C. DeReyck,2 J. Lerut.2

    1Transplant Institute, Henry Ford Health System, Detroit, MI; 2Cliniques Universitaires, Saint-Luc, Bruxelles, Belgium.

    Purpose: Examine whether location or research/teaching demands impacts burnout (emotional exhaustion, depersonalization, personal accomplishment).Method: Cross-sectional survey of American (US) and European (EU) organ transplant surgeons.Results:…
  • 2016 American Transplant Congress

    Liver Transplantation (LT) Using Liver Allografts from Deceased After Cardiac Death (DCD) Donors: Opinions, Practices and Reality.

    L. Sher,1 P. Abt,2 Y. Genyk,1 M. Lo,1 P. Yan,1 L. Ji,1 C. Marsh.3

    1Keck Hospital/University of Southern California, Los Angeles; 2Hospital of the University of Pennsylvania, Philadelphia; 3Scripps Clinic & Green Hospital, San Diego.

    Background: Scientific Studies Committee of ASTS conducted study to identify barriers to use of DCD liver grafts.Objectives: Identify barriers to use of DCD liver allografts;…
  • 2016 American Transplant Congress

    A New Diagnostic Score for Microvascular Inflammation in Antibody-Mediated Rejection in Heart Transplantation.

    M. Racapé,1 A. Loupy,2 R. Guillemain,1 A. François,3 P. Rouvier,4 C. Toquet,5 X. Jouven,1 J. Venner,6 L. Hidalgo,6 J. Reeve,6 P. Bruneval,1 J. Duong Van Huyen,2 P. Halloran.2

    1European Georges Pompidou Hospital, Paris, France; 2Necker Hospital, Paris, France; 3Rouen University Hospital, Rouen, France; 4La Pitié Salpêtrière Hospital, Paris, France; 5Laennec Hospital, Nantes, France; 6University of Alberta, Edmonton, Canada.

    BackgroundThe ISHLT working formulation defines Intravascular Activated Mononuclear Cells (IAMC) as one of the histopathologic features of antibody-mediated rejection (ABMR) in heart transplantation. However, no…
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