2016 American Transplant Congress
Growth of Liver Allografts in Pediatric Transplant Recipients.
Columbia University Medical Center, New York, NY.
IntroductionThe liver's capacity to grow in response to metabolic need is well known. However, the long-term growth of liver allografts transplanted in pediatric patients has…2016 American Transplant Congress
Incidence of Polyoma Virus Associated Nephropathy in a Single Transplant Center Employing a Reduction of Immunosuppression at a Lower Threshold of BK Viremia.
Internal Medicine, Infectious Diseases, Yale University, New Haven, CT.
BackgroundPolyoma virus associated nephropathy (PyVAN) caused by BK virus (BKV) is a major complication occurring in 1-10% of renal transplant recipients. Screening and reduction of…2016 American Transplant Congress
Urinary Tract Infections During the First Year After Renal Transplantation: Risk Factors and Nomograms.
Nephrology, Regional University Hospital, Málaga, Spain.
Background: Urinary tracts infections (UTIs) are the most common infectious complications following renal transplantation (RT). The aim of this study was to evaluate the frequency…2016 American Transplant Congress
Marked Alterations in Gene Expression in Peripheral Blood Leukocytes of Kidney Transplant (tx) Recipients Following Mycophenolic Acid (MPA) Treatment.
1University of Minnestoa, Minneapolis; 2MMRC, Hennepin County Medical Center, Minneapolis; 3Rho.
MPA exerts its immunosuppressive activity by inhibiting IMPDH2 enzyme, halting DNA synthesis in T and B lymphocytes. Cell culture models have shown MPA effects on…2016 American Transplant Congress
Late Renal Allograft Rejection Is Predicted by High Intrapatient Variability of Tacrolimus Levels.
Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.
IntroductionNonadherence to immunosuppressive medication is associated with rejection and graft loss. We have previously shown that intrapatient variability (IPV) of tacrolimus trough levels between 6-12…2016 American Transplant Congress
Initial Experience with Ledipasvir-Sofosbuvir Based Therapy for Recurrent Hepatitis C After Liver Transplantation.
Henry Ford Hospital, Detroit, MI.
Objectives:Evaluate outcomes of Ledipasvir-Sofosbuvir based hepatitis C therapy in liver transplant patients at a single center.Methods:All post-liver transplant patients started on Ledipasvir-Sofosbuvir therapy between January…2016 American Transplant Congress
Serial Peripheral Blood Mononuclear Cell Expression Profiling Reveals Inflammatory Genomic Storm Following Mechanical Circulatory Support Surgery.
Introduction: The main cause of death in patients with Advanced Heart Failure (AdHF) is the Multi-Organ Dysfunction (MOD) Syndrome. Immune system aberrancy after Mechanical Circulatory…2016 American Transplant Congress
Development of a Vascularized Thymus-Sternum Composite Tissue Allograft Model in Non-Human Primates.
Surgery, University of Maryland, Baltimore, MD.
Purpose: Vascularized composite allotransplantation (VCA) has demonstrated clinical success with standard immunosuppressive strategies in face, hand, and forearm transplantations. We developed a non-human primate model…2016 American Transplant Congress
The Medication Level Variability Index (MLVI), a Behavioral Biomarker, Predicts Late Allograft Rejection in Pediatric Liver Transplant Recipients – A Prospective Multisite Study.
Objective: The MALT [Medication Adherence in children who had a Liver Transplant (LT), NCT-01154075, R01DK080740 (NIDDK)] multisite study prospectively evaluated a biomarker for erratic medication…2016 American Transplant Congress
Big Data Predictive Solution to Optimize Kidney Transplant Outcome and Resource Utilization.
Objective: Transplant (Tx) programs often use data in reaction to regulation vs. optimizing outcomes through data driven clinical care. Tx specific issues can detract from…
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