ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Impact of Mixed Xenogeneic Chimerism on Human B Cell Response to Pig Antigens.

    H. Li, S. Shao, P. Vishwasrao, M. Holzl, M. Sykes.

    Columbia Center for Translational Immunology, Columbia University, New York, NY.

    Xenotransplantation is a potential solution to the organ shortage in clinical transplantation. Pigs are regarded as the most suitable donors. Studies in pig-to-nonhuman primates have…
  • 2016 American Transplant Congress

    African Americans Have Greater Odds of Late Stage Diagnosis of Hepatocellular Carcinoma in Mississippi.

    M. Aru, S. Seals, B. Ingram, A. Seawright, C. Anderson, T. Earl.

    Department of Surgery, University of Mississippi Medical Center, Jackson, MS.

    Introduction: Centers for Disease Control Cancer Data show that death rates from HCC exceed expectations from incident rates in Mississippi, therefore we hypothesized that socioeconomic…
  • 2016 American Transplant Congress

    Dynamic Detection of Anti-HLA Antibodies Can Predict aGVHD and OS in HLA-12/12 Matched Unrelated-Donor Allo-HSCT for Hematological Malignancies.

    J. He,1 Z. Pan,1 X. Yuan,1 Y. Li,1 X. Wu,2 W. Zhu,2 X. Bao,1 Q. Zhao.2

    1Department of HLA Laboratory, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China; 2Department of Hematology, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

    The NMDP and CIBMTR provided guidelines for the use of anti-HLA antibodies in unrelated-donors hematopoietic stem cell transplantation (HSCT). However, a deeper understanding of other…
  • 2016 American Transplant Congress

    Long Term Safety of Intravenous Ketorolac Use After Donor Nephrectomy.

    P. Tabrizian,1 M. Giacca,1 J. Prigoff,2 E. Chin,2 M. Palese,2 D. Herron,2 A. Arvelakis,1 D. LaPointe Rudow,1 S. Florman,1 R. Shapiro.1

    1Transplant, Recanati/Miller Transplantation Institute, New York, NY; 2Surgery, Mount Sinai Medical Center, New York, NY.

    Background: The benefit and short-term safety have been established in previous studies; however, the risk of bleeding and long-term renal impairment in patients undergoing donor…
  • 2016 American Transplant Congress

    Does Location Matter for Withdrawal of Donation After Cardiac Death Donors ?

    K. Mekeel,1 W. Garrison,2 J. Trageser,2 J. Berumen,1 L. Stocks,2 A. Hemming.1

    1Surgery, University of California-San Diego, La Jolla, CA; 2Lifesharing, San Diego, CA.

    Purpose: Withdrawal for DCD donors traditionally occurs in the OR. Families often refuse to proceed with DCD donation if they are unable to be present…
  • 2016 American Transplant Congress

    How Tacrolimus Variability Affects Donor Specific Antibodies, Rejection and Outcome After Kidney Transplantation.

    S. Papachristos, A. John Velvet, A. Summers, A. Tavakoli, R. Dhanda, R. Pararajasingam, B. Forgacs.

    Manchester Transplantation Unit, Manchester Royal Infirmary Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.

    Purpose:To investigate the effect of tacrolimus(tac) variability on the development of Donor Specific Antibodies(DSA),rejection and outcome in relation to Age, Gender, Ethnicity and Body Mass…
  • 2016 American Transplant Congress

    Do We Need an Individually Tailored Immunosuppression Strategy for Living Donor Kidney Transplant Recipients with PreTransplant Donor Specific Antibodies? A Retrospective Analysis.

    S. Bhutani,1 A. Ponnusamy,2 Q. Tak,1 S. Shah,1 J. Worthington,1 A. Summers,1 K. Poulton,1 D. Van Dellen,1 M. Morton,1 M. Picton.1

    1Department of Renal & Transplant Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2Department of Renal Medicine, Royal Hospital Preston, Preston, United Kingdom.

    Introduction:Pre-Transplant Microbead donor HLA specific antibody(DSA) positive but cell crossmatch negative transplants are considered to be at increased immunological risk. This study aimed to address…
  • 2016 American Transplant Congress

    Management and Outcomes of Upper Extremity Deep Venous Thrombosis in Heart Transplant Patients.

    A. Panakos,1 D. Kramer,1 M. McCarey,1 P. Mather.2

    1Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA; 2Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA.

    Upper extremity deep venous thrombosis (UEDVT) is common in post-heart transplant (OHT) patients, likely due to their multiple intravascular catheters and post-surgical state. The clinical…
  • 2016 American Transplant Congress

    Four-Factor Prothrombin Complex Concentrate as a Strategy to Rapidly Reverse Anticoagulation in Patients Undergoing Cardiac Transplantation: Better Than the Conventional Approach?

    T. Sam,1 G. Gonzalez-Stawinski,2 G. Saracino,3 A. Jamil,3 S. Hall,2 K. Cox,1 B. Lima.2

    1Department of Pharmacy, Baylor University Medical Center, Dallas, TX; 2Heart Transplantation and Mechanical Circulatory Support, Baylor University Medical Center, Dallas, TX; 3Baylor Research Institute, Baylor University Medical Center, Dallas, TX.

    PurposeThe purpose of this analysis is to compare outcomes of administering four-factor prothrombin complex concentrate (4F-PCC, Kcentra™) versus standard of care for anticoagulation reversal in…
  • 2016 American Transplant Congress

    Basiliximab Induction for Safe Delay of Calcineurin Inhibitors in High MELD Liver Transplant Recipients.

    J. Clark,1 T. Sparkes,1 B. Masters,1 J. LaMattina,2 R. Barth,2 M. Moss.1

    1University of Maryland Medical Center, Baltimore, MD; 2University of Maryland School of Medicine, Baltimore, MD.

    Background: Available literature supports basiliximab induction for safe delay of CNI initiation and renal recovery; however there is a paucity of evidence for use in…
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