ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    iNKT Cell Ligands Administered with Bone Marrow Cells Expand Allo-Specific Regulatory T Cells In Vivo and Establish Transplant Tolerance.

    S. Miyairi,1,2 T. Hirai,1 M. Okumi,1 Y. Ishii,3 K. Yamazaki,2 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan; 3Vaccine Design, RIKEN IMS-RCAI, Yokohama, Japan.

    Invariant natural killer T(iNKT) cells have the powerful potential to expand regulatory T cells(Tregs), especially when they are presented α-galactosylceramide(aGC) by B cells. We previously…
  • 2016 American Transplant Congress

    A Novel Microfluidic Device for Purification of Pancreatic Islet Preparations.

    W. Varhue,1 L. Langman,2 D. Bowers,3 S. Peirce-Cottler,3 N. Swami,1 K. Brayman.2

    1Electrical and Computer Engineering, University of Virginia, Charlottesville, VA; 2Surgery, University of Virginia, Charlottesville, VA; 3Biomedical Engineering, University of Virginia, Charlottesville, VA.

    Purpose: Demonstrate that novel continuous flow microfluidic designs can be utilized to remove contaminating acinar tissue and sort the purified islets, based on size and…
  • 2016 American Transplant Congress

    Thrombalexin: Detection & Efficacy of a Membrane-Bound Anti-Thrombin Agent.

    M. Manook,1,2 J. Kwun,1 J. Yoon,1 S. Sacks,2 A. Dorling,2 N. Mamode,2 R. Smith,2 S. Knechtle.1

    1Surgery, Duke University, Durham; 2King's College, London, United Kingdom.

    Introduction: Early activation of coagulation may be an important factor in the initiation of innate immunity. Anti-coagulation in the transplant setting is difficult due to…
  • 2016 American Transplant Congress

    In Vivo and In Vitro Characterization of 1.5 mm Ba2+-Alginate Macro-Encapsulated Cynomolgus Monkey Islets.

    M. Bochenek,1 J. McGarrigle,1 J. Mendoza-Elias,1 E. Marchese,1 M. Nourmohammadzadeh,1 Y. Wang,1 A. Khan,1 M. Omami,1 C.-C. Yeh,1 I. Lacik,2 B. Strand,3 J. Oberholzer.1

    1Transplant Surgery, University of Iliinois at Chicago, Chicago, IL; 2Biomaterials Research, Polymer Institute of the Slovak Academy of Sciences, Bratislava, Slovakia (Slovak Republic); 3Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway.

    Introduction:Micro-encapsulation of islets for the treatment of Type I diabetes has shown limited efficacy in small-scale clinical trials. The lack of success may be related…
  • 2016 American Transplant Congress

    Diagnosis of Pulmonary Nocardiosis: A Single Center Study.

    D. Wray,1 S. Win,2 M. Heincelman,1 L. Steed,1 J. Cantey.1

    1Medical University of South Carolina, Charleston, SC; 2Los Palos Medical Associates, Salinas, CA.

    Pulmonary nocardiosis (PN) is an uncommon infection seen typically in immunocompromised (IC) patients. Definitive diagnosis depends on culture of nocardia along with a clinical presentation…
  • 2016 American Transplant Congress

    The Preventive and Therapeutic Effect of Immunoglobulin on Infectious Complications in Donation After Cardiac Death Liver Transplant Recipients: A Prospective Randomized Controlled Study.

    A. Yang, Z. Guo, W. Ju, Y. Chen, M. Han, X. Wang, D. Wang, Y. Ma, A. Hu, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims: To prospectively investigate the preventive and therapeutic effect of immunoglobulin on infectious complications in DCD liver transplant recipients, and synthetically evaluate its influence on…
  • 2016 American Transplant Congress

    Post-Trial Experience with Belatacept: A Large Single Center Experience.

    A. Adams, C. Garrett, J. Goldstein, R. Zhang, A. Guasch, S. Pastan, R. Patzer, A. Kirk, T. Pearson, C. Larsen.

    Emory Transplant Center, Atlanta, GA.

    Evaluation of belatacept in clinical trials revealed significant improvements in renal function and cardiovascular risk leading to superior survival. Despite these proven benefits higher rates…
  • 2016 American Transplant Congress

    Vaccination Status and Titers Before and After Pediatric Renal Transplantation: An Analysis of the CERTAIN Registry.

    B. Höcker,1 M. Aguilar,1 P. Schnitzler,2 L. Pape,2 L. Dello Strologo,2 N. Webb,2 M. Bald,2 G. Genc,2 H. Billing,2 J. König,2 A. Büscher,2 F. Thiel,2 S. Marks,2 M. Pohl,2 M. Wigger,2 R. Topaloglu,2 A. Fichtner,1 S. Rieger,1 K. Krupka,1 B. Tönshoff.1

    1University Children's Hospital, Heidelberg, Germany; 2CERTAIN Research Community, Italy, United Kingdom, Turkey, Germany.

    Purpose:Prevention of systemic viral and bacterial infections by effective vaccination in kidney allograft recipients is of vital importance, but data on the vaccination status in…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Cardiovascular Disease After Pediatric Kidney Transplantation.

    O. Serrano,1 A. Bangdiwala,2 D. Vock,2 W. Payne,1 T. Dunn,1 S. Chinnakotla,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas,1 B. Chavers.3

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics, Univ. of Minnesota, Minneapolis, MN; 3Pediatrics, Univ. of Minnesota, Minneapolis, MN.

    PURPOSE: Kidney transplant (KTx) recipients have increased risk of cardiovascular disease (CVD), related to time on dialysis and post-KTx immunosuppression. To date, the incidence of…
  • 2016 American Transplant Congress

    Efficacy of Nine National Policies Reimbursing and Incentivizing Live Organ Donation.

    V. Apte, S. Fry-Revere.

    American Living Organ Donor Network, Lovettsville, VA.

    Background: Organ shortage is a massive global issue, and the high costs of living organ donation only exacerbate the problem. In order to encourage citizens…
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