ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    The Therapeutic Potential of Human Liver-Derived Stem Cell Transplantation in a Cirrhotic Liver Rat Model.

    S. Lee,1 J.-H. Lee,2 H.-J. Park,2 Y.-A. Kim,2 M.-N. Park,2 S.-K. Lee.1

    1Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Stem Cell and Regenerative Medicine Center, Samsung Medical Center, Seoul, Republic of Korea.

    Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Previous studies suggested that MSCs may ameliorate fibrogenesis through…
  • 2016 American Transplant Congress

    IgM Treatment Successfully Prevents Type 1 Diabetes by Dysregulation of Pancreatic MicroRNAs with Immunomodulatory Roles.

    P. Chhabra, R. Gehrau, V. Mas, D. Bower, D. Maluf, K. Brayman.

    UVA, Charlottesville.

    Type 1 Diabetes (T1D) is hallmarked by beta-cells destruction. We aimed to identify specific pancreatic microRNAs (miRNA) as potential biomarkers for T1D prediction and diagnosis,…
  • 2016 American Transplant Congress

    Chemokine Receptor CXCR4 Antagonist, a Novel Pathway to Prevent Chronic Allograft Nephropathy.

    Y. Xu, Q. Zhang, X. Hu.

    Department of Urology, Beijing Chaoyang Hospital, Beijing, China.

    BackgroundChronic allograft nephropathy (CAN) remains a major problem for long term graft survival and different pathways participate in its development. CXC chemokine receptor 4 (CXCR4)…
  • 2016 American Transplant Congress

    Memory Regulatory T Cell: A Potential Actor in Immunological Operational Tolerance in Kidney-Transplant Patients via the ATP Degradation into Adenosine.

    M. Durand,1,2 F. Braza,1 N. Degauque,1 F. Dubois,2 M. Chesneau,1 P. Guérif,1,3 M. Giral,1,3 S. Brouard.1

    1ITUN-INSERM U1064, Nantes, France; 2University of Nantes, Nantes, France; 3Biotherapy Clinical Investigation Center, Nantes, France.

    Regulatory T cells (Tregs) are essential actors in the control of self-tolerance and exacerbated inflammation. In experimental transplantation Tregs are critical to achieve alloantigen tolerance…
  • 2016 American Transplant Congress

    Outcomes of Untreated Asymptomatic Bacteriuria in Renal Transplant Recipients: A Single-Center Experience.

    W. Davis, R.-A. Lee, L. Daniels, S. Todd, K. True, P. Chong.

    University of North Carolina Medical Center, Chapel Hill, NC.

    Background. Renal transplant recipients (RTR) with asymptomatic bacteriuria (AB) are often treated with antibiotics. This could lead to complications related to antibiotic treatment including Clostridium…
  • 2016 American Transplant Congress

    The Effect of the Use of a TNF-Alpha Inhibitor in Hypothermic Machine Perfusion on Kidney Function After Transplantation.

    P. Diuwe,1 P. Domagala,1 R. Kieszek,1 M. Wszola,1 M. Serwanska-Swietek,1 L. Paczek,2 M. Durlik,3 A. Chmura,1 A. Kwiatkowski.1

    1Department of General Surgery and Transplantology, Medical University of Warsaw, Warsaw, Poland; 2Department of Immunology, Transplantology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland; 3Department of Transplantology and Nephrology, Medical University of Warsaw, Warsaw, Poland.

    Organ damage associated with processes occurring during the ischaemic period as well as during and after organ reperfusion is an important problem of transplantation medicine.The…
  • 2016 American Transplant Congress

    A Change in Insulin Sensitivity and Lipid Profile in Renal Transplant Recipients Converted from Cyclosporine or Standard Release Tacrolimus to Once-Daily Prolonged Release Tacrolimus.

    Y. Jung,1 Y. Kim,1 S. Kim,1 H. Shin,1 H. Rim,1 H. Rhew.2

    1Internal Medicine, Kosin University College of Medicine, Busan, Republic of Korea; 2Urology, Kosin University College of Medicine, Busan, Republic of Korea.

    Background : New-onset diabetes after transplantation may be associated with the use of tacrolimus (Tac) causing impaired insulin release or reduced insulin sensitivity. And, dyslipidemia…
  • 2016 American Transplant Congress

    Using 3D Printing in Complex Pediatric Renal Transplantation.

    P. Chandak,1 N. Byrne,2 N. Karunanithy,3 C. Callaghan,1 I. Mushtaq,4 S. Marks,4 J. Stajonovic,1 Z. Ahmed,1 N. Kessaris,1 N. Mamode.1

    1Transplantation, Guy's, Evelina & Great Ormond Street, London, United Kingdom; 2Imaging Sciences, King's College London, London, United Kingdom; 3Interventional Radiology, Guy's, London, United Kingdom; 4Paediatric Nephrology and Urology, Great Ormond Street, London, United Kingdom.

    Introduction:Structural complexities can render graft implantation infeasible in small paediatric recipients. Surgical decision-making currently relies on 3D medical imaging which limits evaluation of structures by…
  • 2016 American Transplant Congress

    Preoperative Cytokine Storm in High MELD Patients Accentuates Incidence of Rejection Following Liver Transplantation.

    A. Mathur, E. Presbyskowski, E. Zorn, K. Rogers, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, T. Kato, J. Emond.

    Abdominal Transplant Surgery, Columbia University, NY, NY.

    IntroductionAcute Cellular Rejection (ACR) affects 30 percent of all liver transplants. Histologically it is characterized by cellular inflammation in the veins, bile ducts and portal…
  • 2016 American Transplant Congress

    A Model to Explore the Potential Budget Impact of a Novel Screening Tool for the Detection of Subclinical Rejection Among Kidney Transplant Patients.

    K. Jaglinski,1 H. Uchida,1 T. Inocencio,2 K. Hughes.2

    1Immucor, Inc, Waukesha, WI; 2Avalare Health, LLC, Washington, DC.

    Background: Acute rejection among kidney transplant patients is common, with ~10% of individuals experiencing acute rejection within the first year and rising to 16-17% at…
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