Am J Transplant, Volume 16, Suppl 3 Archives - Page 74 of 180 - ATC Abstracts

2016 American Transplant Congress
Mesenchymal Stem Cells Reprogram Macrophage Polarization and Attenuate Liver Ischemia and Reperfusion Injury by Regulating Notch/Cox2/PGE2 Signaling Pathway.
C. Li,¹ S. Yue,¹ R. Busuttil,¹ J. Kupiec-Weglinski,¹ B. Ke.¹
¹The Dumont-UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA; ²Department of Physiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.
Background and aims: Mesenchymal stem cells (MSCs) have been shown an immune modulatory properties and tissue repairing capability under inflammatory conditions. However, it is unknown…
2016 American Transplant Congress
Creation of a Small Animal Model of Ex-Vivo Normothermic Perfusion (EVNP) for Treatment of Kidney Ischemia-Reperfusion (I/R) Injury.
Y. Smolin, I. Palma, C. Pivetti, S. Kabagambe, J. Woloszyn, Y. Chen, T. Boyer, I. Palma, J. Sageshima, C. Santhanakrishnan, R. Perez.
Department of Surgery, UC Davis Medical Center, Sacramento, CA.
Purpose: Recent studies have suggested that EVNP may be utilized to assess and repair marginal donor organs subjected to severe I/R injury. The lack of…
2016 American Transplant Congress
Prolonged Cold Ischemia Time Negatively Impacts Graft and Recipient Survival in a Murine Orthotopic Hindlimb Transplant Model.
N. Datta, S. Devaney, A. Allen, R. Busuttil, K. Azari, J. Kupiec-Weglinski.
Department of Surgery, UCLA Medical Center, Los Angeles, CA.
Purpose: The safe maximum cold preservation time remains unknown in Vascularized Composite Allotransplantation (VCA), yet is of critical clinical significance. VCAs with a large muscular…
2016 American Transplant Congress
Living Kidney Donor Preferences: A Novel Use of a Visual Instrument to Quantify ESRD Risk Acceptance.
C. Thiessen,¹ J. Gannon,¹ D. Dobosz,¹ S. Li,¹ D. Gray,² A. Mussell,² K. Kennedy,³ L. Skrip,¹ E. Gordon,³ P. Reese,² S. Kulkarni.¹
¹Yale U, New Haven; ²U Pennyslvania, Philadelphia; ³Northwestern U, Chicago.
BackgroundGiven new data about the estimated lifetime risk of ESRD among living kidney donors (LKD) (Muzaale 2014), we elicited their willingness to accept the risk…
2016 American Transplant Congress
Low-Pressure Pneumoperitoneum in Living Kidney Donors: An Age-Dependent Analysis of Recipient Outcomes.
S. Kulkarni,¹ S. Douglas,² E. Cohen,¹ S. Swift,¹ I. Hall.²
¹Surgery, Yale University School of Medicine, New Haven, CT; ²Medicine, Yale University School of Medicine, New Haven, CT.
Purpose: Implementation of low-pressure laparoscopy may be facilitated by the use of valveless, recirculating trocar systems that have less intra-abdominal pressure variability, providing adequate surgical…
2016 American Transplant Congress
Hydrogen Sulfide Supplementation Helps Mitigate Effects of Ischemia Reperfusion Injury in a Murine Model of Donation After Cardiac Death Renal Transplantation.
J. Grewal,¹ I. Lobb,¹ M. Saha,² J. Jiang,² A. Haig,¹ A. Sener.^1,2
¹Microbiology & Immunology, University of Western Ontario, London, Canada; ²Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, Canada.
Donation after cardiac death(DCD) renal grafts experience a combination of prolonged warm and cold ischemia leading to greater ischemia reperfusion injury(IRI) that results in higher…
2016 American Transplant Congress
Imminent Death Donation: Potential Effects on Organ Donation Numbers and Clinical Outcomes.
V. Potluri,¹ S. Nazarian,² M. Levine,² P. Reese.³
¹Internal Medicine, Lankenau Hospital, Wynnewood; ²Transplant Surgery, University of Pennsylvania, Philadelphia; ³Renal Division, University of Pennsylvania, Philadelphia.
Attempts at donation after cardiac death (DCD) lead to organ transplantation only among 70% of eligible DCDs. Imminent death donation (IDD) is ante-mortem donation of…
2016 American Transplant Congress
Cholangioscopy in Liver Transplant Recipients.
U. Agbim,¹ E. Verna,¹ R. Brown, Jr,² A. Sethi.¹
¹Columbia University, New York; ²Cornell University, New York.
BackgroundBiliary complications in the post-liver transplant population are common and are a source of significant morbidity, which are preferably managed, if technically feasible, by endoscopic…
2016 American Transplant Congress
Incidence of and Risk Assessment for Adverse Cardiovascular Outcomes Following Liver Transplantation: A Systematic Review.
M. Konerman,¹ D. Fritze,² R. Weinberg,³ E. Spengler,¹ C. Sonnenday,² P. Sharma.¹
¹Hepatology, Univ of Michigan, Ann Arbor, MI; ²Transplantation Surgery, Univ of Michigan, Ann Arbor, MI; ³Cardiology, Univ of Michigan, Ann Arbor, MI.
Purpose: Cardiovascular (CV) events remain a major source of morbidity and mortality following liver transplantation (LT). This review evaluates the incidence of and risk assessment…
2016 American Transplant Congress
Incidence, Risk Factors and Treatment of Incisional Hernia After Kidney Transplantation – An Analysis of 1564 Consecutive Patients.
L. Ooms,¹ J. Verhelst,¹ J. Jeekel,² J. IJzermans,¹ J. Lange,¹ T. Terkivatan.¹
¹Surgery, Erasmus MC, University Medical Center, Rotterdam, Netherlands; ²Neuroscience, Erasmus MC, University Medical Center, Rotterdam, Netherlands.
Purpose The objective was to evaluate the incidence and treatment of incisional hernia following kidney transplantation, and to identify potential risk factors.Methods A retrospective cohort…