Am J Transplant, Volume 16, Suppl 3 Archives - Page 73 of 180 - ATC Abstracts

2016 American Transplant Congress
Chronic High Epstein-Barr Viral Load Carriage in Pediatric Kidney Transplant Recipients.
M. Yamada,¹ P. Fadaker,¹ C. Nguyen,¹ A. Ganoza,² A. Humar,² M. Michaels,^1,2 M. Green.^1,2
¹Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA; ²Surgery, University of Pittsburgh, Pittsburgh, PA.
BackgroundThe development of Epstein-Barr virus (EBV) infection and post-transplant lymphoproliferative disorder (PTLD) is normally associated with a high EBV viral load in peripheral blood. Observations…
2016 American Transplant Congress
The Effect of Tocilizmab Treatment (TCZ-Rx) on IgG Subclasses in HLA-sensitized (HS) Kidney Transplant Patients Treated with TCZ.
B.-H. Shin, S. Ge, J. Choi, J. Kahwaji, A. Vo, A. Petrosyan, S. Jordan, M. Toyoda.
Transplant Immunology Laboratory and Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Antibody-mediated rejection (ABMR) is a major obstacle for successful transplant in HS patients. TCZ has anti-B cell and anti-inflammatory properties. We have reported its…
2016 American Transplant Congress
Optimized Flow Cytometry Crossmatch with Increased Sensitivity and Specificity.
K. Barrios,¹ J. Lunz,¹ B. Labuda,¹ D. Magas,¹ D. Freedom,¹ K. Szewczyk,¹ M. Jendrisak,¹ A. Jaramillo.^1,2
¹Gift of Hope Organ & Tissue Donor Network, Itasca, IL; ²Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ.
The flow cytometry crossmatch (FCXM) is the standard method to prevent hyperacute rejection after transplantation. Surprisingly, few technical improvements have been introduced to the FCXM…
2016 American Transplant Congress
Outcomes in Elderly Renal Transplant Recipients Using Thymoglobulin or Interleukin-2 Receptor Antagonist Induction.
N. Jasiak,¹ J. Thielke,¹ J. Chen,² N. Hilal,¹ S. Salah,¹ D. Wu,¹ E. Benedetti,² P. West-Thielke.^1,2
¹Pharmacy, University of Illinois, Chicago; ²Transplant Surgery, University of Illinois, Chicago.
Background: Approximately 20% of all renal transplants performed in the US in 2014 occurred in elderly patients. Elderly patients are known to be at higher…
2016 American Transplant Congress
Time Trends of Induction Agent Use in Older and Younger Kidney Transplantation Recipients.
Q. Huang, X. Luo, M. McAdams-DeMarco, D. Segev.
Johns Hopkins University, Baltimore, MD.
Older adults are increasingly gaining access to kidney transplantation (KT) yet the use of induction agents in this population is unclear. The goal of this…
2016 American Transplant Congress
Are Random Tacrolimus Levels in the Emergency Department Costing You Money?
B. Lee, D. Jain, M. Campara.
University of Illinois at Chicago, Chicago.
Purpose: Tacrolimus (TAC) is the most frequently used immunosuppressant in the USA today, with a narrow therapeutic index that requires frequent 12-hour trough monitoring and…
2016 American Transplant Congress
The Fine-Tuning of CXCL8 Protects Kidney Against Ischemia-Reperfusion Injury in Mice Lacking MicroRNA-146a.
L. Amrouche,^1,2 G. Desbuissons,¹ M. Rabant,^1,2 C. Legendre,^1,2 F. Terzi,² D. Anglicheau.^1,2
¹U1151, INSERM, Paris, France, Metropolitan; ²Department of Kidney Transplantation, Necker hospital, Paris, France, Metropolitan.
Acute kidney injury leads to the development of tubular injury and interstitial inflammation that need to be controlled to avoid fibrosis development. We hypothesized that…
2016 American Transplant Congress
Subnormothermic Machine Perfusion (SNMP) with a Hemoglobin Based Oxygen Carrier (HBOC) Solution Reprograms Dynamic Inflammation Networks When Compared to Cold Storage (CS) in a Porcine Liver Allograft Model.
D. Sadowsky, R. Zamora, B. Banan, D. Barclay, J. Yin, Y. Vodovotz, P. Fontes.
University of Pittsburgh, Pittsburgh.
Introduction: Inflammatory markers have been mostly studied by standard statistical analysis focused on single component variations. This study aimed to compare SNMP with CS regarding…
2016 American Transplant Congress
C1-Inhibitor Abrogated Ischemia/Reperfusion (I/R) Induced Inflammaging by Inhibiting Senescence-Associated Secretory Phenotype (SASP) in Tubular Epithelial Cells (TEC).
G. Castellano,¹ R. Franzin,¹ A. Stasi,¹ C. Divella,¹ M. Gigante,¹ S. Simone,¹ A. Intini,¹ A. Picerno,¹ P. Pontrelli,¹ A. Crovace,¹ M. Battaglia,¹ B. Oortwijn,² E. Amersfoort,² G. Grandaliano,³ L. Gesualdo.¹
¹Department of Emergency and Organ Transplantation, University of Bari, Bari, Italy; ²Pharming Technologies, Leiden, Netherlands; ³Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Inflammaging is a pathogenic process usually associated with chronic kidney disease such as diabetic nephropathy where TEC cells have a diminished regenerative potential and develop…
2016 American Transplant Congress
What Are the Benefits of Transvaginal Route for Kidney Extraction in Laparoscopic Living Donor Nephrectomy ?
S. Hurel,¹ M. Ariane,¹ F. Audenet,¹ C. Legendre,² A. Mejean,¹ M.-O. Timsit.¹
¹Hôpital Européen Georges Pomidou, Paris, France; ²Hôpital Necker, Paris, France.
Rationale and objectivesTransvaginal route for kidney extraction (TVE) emerged as new surgical option during laparoscopic donor nephrectomy to minimize scar and presumably to offer donors…