2016 American Transplant Congress
Potent Induction Therapy Improves Graft Outcome in Younger Pancreas Transplant Recipients (<30 Years of Age).
SUNY Upstate Medical University, Syracuse, NY.
Purpose: Pancreas transplants (tx) are increasingly performed in older patients with type 1 diabetes mellitus. This trend may be explained by the significantly higher immunologic…2016 American Transplant Congress
The First Impressions: A Study in Pre and Post-Implantation Renal Grafts for Early Detection Markers of Delayed Graft Function and Recovery.
1UVA, Charlottesville; 2VCU, Charlottesville; 3Northwestern University, Chicago.
Background: Delayed graft function (DGF) is mainly a consequence of ischemia and reperfusion injury (IRI) resulting in acute tubular necrosis. The degree of IRI is…2016 American Transplant Congress
Variation in Co-Medication Use According to Kidney Transplant Immunosuppressive Regimen: Application of Integrated Registry and Pharmacy Claims Data.
Background: While modern immunosuppressive therapies (ISx) have substantially reduced acute rejection, ISx medications have many side effects, and transplant recipients must take an array of…2016 American Transplant Congress
Early Post-Transplant Patient, Graft Survival and Rejection Rates Under KAS.
Background: KAS, implemented on 12/4/14, resulted in changes in recipient, donor/recipient and tx characteristics that have the potential to affect post-tx outcomes.Data and Methods: We…2016 American Transplant Congress
Primary Outcome of iWITH: A Multi-Center Clinical Trial of Complete Immunosuppression Withdrawal (ISW) in Stable Pediatric Liver Transplant (LT) Recipients.
AIM: Test the hypothesis that a selected cohort of pediatric LT recipients can safely undergo complete ISW followed by assessment for operational tolerance (OT)METHODS: 88…2016 American Transplant Congress
Skipping Comparable Local Waitlist Candidates Under Share 35.
1Surgery, Johns Hopkins University, Baltimore, MD; 2Mathematics, US Naval Academy, Annapolis, MD.
Under Share-35, deceased donor (DD) livers are offered regionally to candidates with MELD≥35 before locally to lower MELD candidates. The characteristics and outcomes of local…2016 American Transplant Congress
Are We Refusing Good Organs? Outcomes of Ventilator Management of Sub-Optimal Lung Donors.
PurposeOptimizing donor lung function is essential for organ acceptance and successful lung transplantation (LTx). We hypothesized that ventilator management of sub-optimal donor lungs, PaO2<300 mmHg,…2016 American Transplant Congress
High Incidence of Herpes Zoster After Kidney, Liver, Heart and Lung Transplantation.
Erasmus MC, Rotterdam, Netherlands.
Background: Primary varicella zoster virus (VZV) infection causes varicella and lifelong latent infection in neural ganglia from which it may reactivate leading to herpes zoster…2016 American Transplant Congress
Solid Phase Assay Demonstrates High Rates of Allosensitization in Pediatric Heart Recipients.
Allosensitization is a risk factor for rejection, vasculopathy and graft loss. CTOTC-04 is a prospective study assessing the impact of sensitization on a composite of…2016 American Transplant Congress
T-Bet Regulates nTreg Stability and Suppression in an Islet Allograft Model.
University of Maryland, Baltimore.
The transcription factor T-bet endows Treg with properties tosuppress Th1 inflammation. However, the mechanisms by which T-bet controls alloimmune responses are not fully understood. We…
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