ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Influence of Country-Associated Geographical Variables in the Ouctomes of Kidney Transplantation in Patients with HIV-Infection.

    M. Cristelli,1 F. Cofán,2 H. Tedesco-Silva,1 J. Trullas,3 D. Santos,1 C. Manzardo,4 F. Aguero,4 A. Moreno,4 F. Oppenheimer,2 F. Dieckmann,1 J. Miro,4 J. Medina-Pestana.1

    1Hospital do Rim-UNIFESP, São Paulo, Brazil; 2Nephrology, Hospital Clinic-IDIBAPS, Barcelona, Spain; 3Hospital de Olot, Girona, Spain; 4Infectology, Hospital Clinic-IDIBAPS, Barcelona, Spain.

    Objective: To evaluate effects of geographical factors on demography, clinical management and evolution of two cohorts of HIV-infected KT recipients.Methods: Observational, retrospective cohort study including…
  • 2016 American Transplant Congress

    The Phenotypic Diversity of Late Silent Antibody-Mediated Rejection.

    F. Eskandary,1,2 J. Reeve,1,3 H. Regele,4 L. Hidalgo,1,3 D. Yoo,1 N. Kozakowski,4 K. Famulski,1 G. Böhmig,2 P. Halloran.1,5

    1Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada; 2Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; 3Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada; 4Department of Clinical Pathology, Medical University of Vienna, Vienna, Austria; 5Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, AB, Canada.

    Study purpose: ABMR is a driving force of long-term allograft loss in organ transplantation. The present study was designed to characterize the phenotypic diversity of…
  • 2016 American Transplant Congress

    Diffuse Extent of Peritubular Capillaritis in Late Antibody Mediated Rejection Is Associated with More Severe Chronic Allograft Damage.

    Z. Kikić,1 F. Eskandary,1 H. Herkner,2 R. Oberbauer,1 G. Bond,1 H. Regele,3 G. Böhmig,1 N. Kozakowski.3

    1Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; 2Emergency Medicine, Medical University of Vienna, Vienna, Austria; 3Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.

    Peritubular capillaritis (ptc) is a widely accepted histologic criterion of antibody-mediated rejection (ABMR), and while the ptc score is incorporated in current diagnostic recommendations, the…
  • 2016 American Transplant Congress

    iNKT Cell Ligands Administered with Bone Marrow Cells Expand Allo-Specific Regulatory T Cells In Vivo and Establish Transplant Tolerance.

    S. Miyairi,1,2 T. Hirai,1 M. Okumi,1 Y. Ishii,3 K. Yamazaki,2 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan; 3Vaccine Design, RIKEN IMS-RCAI, Yokohama, Japan.

    Invariant natural killer T(iNKT) cells have the powerful potential to expand regulatory T cells(Tregs), especially when they are presented α-galactosylceramide(aGC) by B cells. We previously…
  • 2016 American Transplant Congress

    A Novel Microfluidic Device for Purification of Pancreatic Islet Preparations.

    W. Varhue,1 L. Langman,2 D. Bowers,3 S. Peirce-Cottler,3 N. Swami,1 K. Brayman.2

    1Electrical and Computer Engineering, University of Virginia, Charlottesville, VA; 2Surgery, University of Virginia, Charlottesville, VA; 3Biomedical Engineering, University of Virginia, Charlottesville, VA.

    Purpose: Demonstrate that novel continuous flow microfluidic designs can be utilized to remove contaminating acinar tissue and sort the purified islets, based on size and…
  • 2016 American Transplant Congress

    Thrombalexin: Detection & Efficacy of a Membrane-Bound Anti-Thrombin Agent.

    M. Manook,1,2 J. Kwun,1 J. Yoon,1 S. Sacks,2 A. Dorling,2 N. Mamode,2 R. Smith,2 S. Knechtle.1

    1Surgery, Duke University, Durham; 2King's College, London, United Kingdom.

    Introduction: Early activation of coagulation may be an important factor in the initiation of innate immunity. Anti-coagulation in the transplant setting is difficult due to…
  • 2016 American Transplant Congress

    In Vivo and In Vitro Characterization of 1.5 mm Ba2+-Alginate Macro-Encapsulated Cynomolgus Monkey Islets.

    M. Bochenek,1 J. McGarrigle,1 J. Mendoza-Elias,1 E. Marchese,1 M. Nourmohammadzadeh,1 Y. Wang,1 A. Khan,1 M. Omami,1 C.-C. Yeh,1 I. Lacik,2 B. Strand,3 J. Oberholzer.1

    1Transplant Surgery, University of Iliinois at Chicago, Chicago, IL; 2Biomaterials Research, Polymer Institute of the Slovak Academy of Sciences, Bratislava, Slovakia (Slovak Republic); 3Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway.

    Introduction:Micro-encapsulation of islets for the treatment of Type I diabetes has shown limited efficacy in small-scale clinical trials. The lack of success may be related…
  • 2016 American Transplant Congress

    Diagnosis of Pulmonary Nocardiosis: A Single Center Study.

    D. Wray,1 S. Win,2 M. Heincelman,1 L. Steed,1 J. Cantey.1

    1Medical University of South Carolina, Charleston, SC; 2Los Palos Medical Associates, Salinas, CA.

    Pulmonary nocardiosis (PN) is an uncommon infection seen typically in immunocompromised (IC) patients. Definitive diagnosis depends on culture of nocardia along with a clinical presentation…
  • 2016 American Transplant Congress

    The Preventive and Therapeutic Effect of Immunoglobulin on Infectious Complications in Donation After Cardiac Death Liver Transplant Recipients: A Prospective Randomized Controlled Study.

    A. Yang, Z. Guo, W. Ju, Y. Chen, M. Han, X. Wang, D. Wang, Y. Ma, A. Hu, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims: To prospectively investigate the preventive and therapeutic effect of immunoglobulin on infectious complications in DCD liver transplant recipients, and synthetically evaluate its influence on…
  • 2016 American Transplant Congress

    Post-Trial Experience with Belatacept: A Large Single Center Experience.

    A. Adams, C. Garrett, J. Goldstein, R. Zhang, A. Guasch, S. Pastan, R. Patzer, A. Kirk, T. Pearson, C. Larsen.

    Emory Transplant Center, Atlanta, GA.

    Evaluation of belatacept in clinical trials revealed significant improvements in renal function and cardiovascular risk leading to superior survival. Despite these proven benefits higher rates…
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