Am J Transplant, Volume 16, Suppl 3 Archives - Page 68 of 180 - ATC Abstracts

2016 American Transplant Congress
Effect of mTOR Inhibitors on the Risk of Cancer Development After Kidney Transplantation in Chinese Population.
C.-C. Kao,¹ J.-S. Liu,² M.-H. Lin,² F.-C. Chang,¹ Y.-C. Lin,¹ H.-H. Chen,¹ T.-W. Chen,¹ C.-C. Hsu,² M.-S. Wu.¹
¹Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan; ²Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Introduction The mTOR inhibitor is an immunosuppressive drug used in kidney transplantation. Whether the mTOR inhibitors is associated with reduced risk of cancer development in…
2016 American Transplant Congress
Everolimus (EVR) versus Mycophenolate Sodium (MPS) for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin (r-ATG) and Tacrolimus (TAC).
H. Tedesco-Silva,¹ C. Felipe,¹ A. Brigido,¹ A. Bessa,¹ M. Paula,¹ P. Ruppel,¹ M. Cristelli,¹ L. Viana,¹ G. Basso,¹ M. Franco,² W. Aguiar,¹ J. Medina-Pestana.¹
¹Nephrology Division, Hospital do Rim - UNIFESP, Sao Paulo, Brazil; ²Pathology Division, UNIFESP, Sao Paulo, Brazil.
Introduction: There is no standard of care immunosuppressive regimen for recipients of kidneys recovered from expanded criteria donors. Several centers use r-ATG induction due to…
2016 American Transplant Congress
Crisis on the Waiting List for Children Listed in Low Volume Solid Organ Transplant Centers.
A. Rana, E. Brewer, W. Winkelmayer, C. O'mahony, J. Goss.
Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Purpose: In a recent analysis, we demonstrated that children listed in low volume liver transplant centers had poor waitlist survival and a depressed transplant rate…
2016 American Transplant Congress
Utilization of HCV-Positive Donors' Kidneys: Potential Benefits in the Era of Direct Acting Antiviral (DAA) Therapy.
B. Amundsen,¹ M. Sise,² M. Lin,³ H. Deirawan,¹ E. Heher,² B. Kimball,¹ J. Markmann,¹ N. Elias.¹
¹Massachusetts General Hospital, Boston, MA; ²Massachusetts General Hospital, Boston, MA; ³Brigham and Women's Hospital, Boston, MA.
Organ shortage and expanding kidney waiting list fostered utilization of HCV positive donors' organs (HCVD+). HCVD+ kidneys have slightly worse long term outcomes compared with…
2016 American Transplant Congress
HO-1/SIRT1/p53 Axis Regulates Macrophage Activation and Attenuates Liver Ischemia-Reperfusion Injury in Mice.
K. Nakamura,¹ M. Zhang,² B. Ke,¹ S. Kageyama,¹ R. Busuttil,¹ J. Araujo,² J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, University of California-Los Angeles, Los Angeles, CA; ²Medicine, Division of Cardiology, University of California-Los Angeles, Los Angeles, CA.
Background/Aim: The mechanism by which macrophage heme oxygenase-1 (HO-1)-Sirtuin1 (SIRT1) signaling promotes resistance against inflammation response in liver ischemia-reperfusion injury (IRI) remains elusive. As tumor…
2016 American Transplant Congress
Thoracic Simulation Allocation Modeling (TSAM) of a 6-Tier Allocation Strategy.
M. Colvin,¹ M. Skeans,¹ L. Robbins Callahan,² L. Edwards,² J. Zeglin,¹ S. Silvestry,³ R. Davies,⁴ M. Farr,⁵ A. Israni,¹ J. Rogers.⁶
¹SRTR, Minneapolis; ²UNOS, Richmond; ³Florida Hospital Transplant Inst, Orlando; ⁴Nemours/AI duPont Hosp for Children, Wilmington; ⁵Columbia Univ Medical Center, New York; ⁶Duke Univ, Durham.
Heart allocation policy (OPTN policy 6) is in development. To stratify medical urgency, the Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tier algorithm…
2016 American Transplant Congress
Are Prior Living Kidney Donors with ESRD Being Listed and Receiving Transplantation Priority in a Timely Manner?
J. Wainright, A. Kucheryavaya, D. Klassen, D. Stewart.
UNOS, Richmond, VA.
BackgroundPrior living donors (PLDs) receive very high priority on the kidney (KI) waiting list (WL). Programs must submit requests for PLD priority to the UNOS…
2016 American Transplant Congress
Post-Transplant Monitoring of Donor-Specific Anti-HLA Antibodies and Their Characteristics Improves Risk Stratification of Kidney Allograft Loss.
D. Viglietti,¹ A. Loupy,² C. Bentlejewski,³ C. Legendre,² D. Glotz,¹ A. Zeevi,³ C. Lefaucheur.¹
¹Saint-Louis Hospital, Paris, France; ²Necker Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
Circulating donor-specific anti-HLA antibodies (DSA) are associated with allograft failure in solid-organ transplantation. We investigated the pathogenic characteristics of DSA that may improve risk prediction…
2016 American Transplant Congress
Geographic Differences in Racial Disparity Reduction in Kidney Transplant Rates Before and After the New Kidney Allocation System.
R. Patzer,¹ T. Melanson,¹ M. Basu,¹ L. Plantinga,¹ L. McPherson,¹ S. Mohan,² J. Gander,¹ D. Howard,¹ S. Pastan.¹
¹Emory University, Atlanta; ²Columbia University, New York.
Background: Prior to the new kidney allocation system (KAS) implemented 12/4/2014, significant African American (AA) vs. white racial disparities existed in access to kidney transplantation…
2016 American Transplant Congress
Black Ethnicity as a Risk Factor for Poor Kidney Allograft Outcomes Post-Transplantation.
S. Tahir,¹ F. Jackson-Spence,¹ H. Gillott,¹ F. Everson,² J. Nath,² A. Sharif.²
¹University of Birmingham, Birmingham, United Kingdom; ²Queen Elizabeth Hospital, Birmingham, United Kingdom.
Introduction: Registry studies, largely from the United States, have consistently demonstrated inferior outcomes for black patients undergoing renal transplant. A recent Canadian publication has challenged…