2016 American Transplant Congress
PD-L1/PD-L2-Expressing B-1a Cells Inhibit Allo-Reactive T Cells in Mice.
Donor lymphocyte infusion (DLI) induces donor-specific hypo responsiveness or immune-tolerance among allo-reactive T cells in different organ transplantation models. However, the optimal cell source or…2016 American Transplant Congress
Sequential Analysis of Donor-Specific Antibodies and Pathological Findings Using Intravenous Immunoglobulin in a Highly Sensitized Rat Kidney Transplant Model.
Intravenous immunoglobulin (IVIG) has evolved widespread use for treatment of acute antibody-mediated rejection (AAMR) and desensitization in highly HLA-sensitized patients. However, sequential change of the…2016 American Transplant Congress
In Vitro Induction of T Regulatory Cells by Multipotent Adult Progenitor Cells.
Regenerative Medicine, Athersys, Inc, Cleveland, OH.
There is increasing evidence that transplanted adult stemcells remain undifferentiated and often are cleared after a short time.However, these short-lived stem cells still promote recovery…2016 American Transplant Congress
Use of Integrated National Registry and Pharmacy Claims Data to Identify Diabetes Mellitus After Live Pancreas Donation.
Living donor pancreas transplant is a potential treatment for diabetic patients with end-organ complications. Early post-donation surgical risks of living pancreas donation have been reported,…2016 American Transplant Congress
Utilization of Plasmapheresis and High Dose of Immunoglobulins in the Treatment of the High Level of De Novo Donor Specific Antibodies for the Successful Islet Allotransplantation.
Background.Development of donor specific antibodies (DSA) after islet transplantation has been a poor prognostic factor for graft survival, while no intervention is implemented. Here, we…2016 American Transplant Congress
Periodical Peer Review of a Pancreas Transplant Programme: Can It Enhance Performance?
Introduction:In the UK, NHS Blood and Transplant (NHSBT), the national transplant regulatory body, monitors 30-day graft loss and patient mortality by CUmulative SUMmation methodology (CUSUM).…2016 American Transplant Congress
Enabled PRA and Precision PRA: Alternatives to cPRA as Desensitization Trial Endpoints.
U of Cincinnati, Cincinnati; Mayo Clinic Scottsdale, Scottsdale.
Transplant (Transplant) rate is an optimal endpoint in desensitization (DS) trials in HLA sensitized Txp candidates, however, for waitlisted Txp candidates, wait time heterogeneity compromises…2016 American Transplant Congress
The Prevailing Preference for Left Nephrectomy in Living Donor Transplantation Does Not Adversely Affect Long Term Donor Outcome.
Background: There is a world-wide prevailing clinical bias for removing the left kidney for living donor renal transplant. Both the retrieval and implantation of the…2016 American Transplant Congress
Gender Bias and Kidney Transplantation in Nepal.
1JHU, Baltimore; 2BPKIHS, Dharan, Nepal; 3Human Organ Transplant Center, Bhaktapur, Nepal.
Gender bias in live kidney donation (LKD) is well documented globally but is particularly extreme in Nepal, where 84% of recipients, but only 25% of…2016 American Transplant Congress
A Novel Quantitative CD45 Immunofluorescence Assay Can Measure Inflammatory Load in Renal Transplant Biopsies with Excellent Reproducibility and Repeatability.
1UCSF, San Francisco, CA; 2Rho, Chapel Hill, NC.
Purpose: The interobserver reproducibility of the current standard semiquantitative (Banff) grading of inflammation in renal transplant biopsies (TxBx) is suboptimal. We have recently developed a…
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