ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Real Time Assessment of Kidney Transplant Indication Biopsies by Microarrays: First Results of the INTERCOMEX Study.

    P. Halloran,1,2 J. Reeve,1 INTERCOMEX Study Group.

    1University of Alberta, Edmonton, Canada; 2ATAGC, Edmonton, Canada.

    Oncology uses central molecular tissue assessment (MTA) to guide management but the potential of this approach in transplantation is not known. We undertook a prospective…
  • 2016 American Transplant Congress

    Costimulation Blockade by Anti CD40 Antibody Prevents Humoral and Cellular Rejection of Heterotopic Pig Cardiac Xenograft.

    A. Singh,1 J. Chan,1 P. Corcoran,1 B. Lewis,2 M. Thomas,2 D. Ayares,3 K. Horvath,1 M. Mohiuddin.1

    1CSRP/NHLBI, NIH, Bethesda, MD; 2DVR/ORS, NIH, Bethesda, MD; 3Revivicor Inc., Blacksburg, VA.

    BackgroundXenotransplantation (XTx) involves the participation of innate immune system with natural antibody producing B cells, NK cells, macrophages and complement as well as adaptive immune…
  • 2016 American Transplant Congress

    Innate Lymphoid Cells Play a Key Role in Controlling Antimicrobial Defense in Intestinal Transplant Recipients.

    J. Kaiser, C. Cosentino, A. Shukla, C. Desai, R. Girlanda, J. Hawksworth, C. Matsumoto, M. Zasloff, T. Fishbein, A. Kroemer.

    MedStar Georgetown Transplant Institute, Washington DC.

    A. Infectious complications are the leading cause of death early after intestinal transplantation (ITx). Etiologies underlying this remain unclear. Innate lymphoid cells (ILCs) have very…
  • 2016 American Transplant Congress

    Delays in the Live Kidney Donor Evaluation Process.

    J. Leanza, K. Kumar, J. Tonascia, E. King, A. Massie, D. Segev.

    JHU, Baltimore.

    One of the barriers to live kidney donation (LKD) is successful completion of the evaluation process. While it is known that many potential donors (PDs)…
  • 2016 American Transplant Congress

    Hepatic Hemodynamics (HD) and Portal Flow Modulation (PM): Tactical Use in Small for Size (SFS) Live Donor Liver Transplantation (LDLT).

    T. Mansour,1 J. Pisa,1 E. Przybyszewski,1 J. Guarrera,1 K. Tomoaki,1 B. Samstein,1 K. Halazun,2 A. Griesemer,1 J. Emond.1

    1Surgery, Columbia University Medical Center, New York; 2Surgery, Weill Cornell Medical Center, New York.

    Objectives:Efforts to reduce the risk of donor hepatectomy have resulted in smaller grafts for transplantation. Grafts below 0.8% of recipient body weight (GW/RW), have been…
  • 2016 American Transplant Congress

    HLA Class II and BK Virus Reactivation in Renal Transplant Recipients.

    P. Shah,1 K. Anderson,2 M. Aubrey,2 C. Roark,2 B. Freed,2 A. Wiseman.1

    1Division of Renal Diseases and Hypertension, University of Colorado School of Medicine, Aurora, CO; 2Division of Immunology, University of Colorado School of Medicine, Aurora, CO.

    BK Viremia (BKV) and subsequent BK nephropathy are associated with renal graft loss. The Human Leukocyte Antigen (HLA) region has been implicated in susceptibility to…
  • 2016 American Transplant Congress

    Understanding the Drivers Behind an Early Post-KAS Rise in Delayed Graft Function (DGF) Rates.

    D. Stewart, A. Kucheryavaya, D. Klassen.

    UNOS, Richmond, VA.

    Background: DGF among solitary deceased donor kidney transplants (tx) increased by 22% (p<0.0001) -- from 24.6% to 30.1% -- during the first 6 months of…
  • 2016 American Transplant Congress

    P-Glycoprotein Function: Association with Race, Gender and Tacrolimus Pharmacokinetics.

    K. Tornatore,1,4 H. Minderman,2 K. Attwood,3 K. O'Loughlin,2 R. Venuto.4

    1Translational Pharmacology Research, School of Pharmacy, Buffalo; 2Flow Cytometry Laboratory, Roswell Park Cancer Institute, Buffalo; 3Biostatistics, School of Public Health, Buffalo; 4Medicine, School of Medicine;UB, Buffalo.

    Background: Long term allograft survival remains poorer in African American(AA) renal transplant recipients(RTR) compared to Caucasians(C) and may be due to racial differences in calcineurin…
  • 2016 American Transplant Congress

    Outcomes Following Inguinal Hernia Repair in Kidney Transplant Recipients.

    S. DiBrito, I. Olorundare, C. Landazabal, D. Segev, N. Dagher.

    Transplant Surgery, Johns Hopkins Hospital, Baltimore.

    It is assumed that kidney transplant (KT) recipients have more complications, longer length of stay (LOS) and higher hospital cost associated with general surgery procedures,…
  • 2016 American Transplant Congress

    Early Post-Transplant Immunosuppression (IS) Withdrawal – Final Outcomes of the ITN030ST AWISH Study.

    A. Shaked,1 S. Feng,2 J. Punch,3 J. Reyes,4 J. Levitsky,5 G. Klintmalm,6 H. Kopetskie,7 M. DesMarais,2 A. Priore,8 N. Bridges,8 P. Sayre.2

    1UPenn, Philadelphia; 2UCSF, San Francisco; 3U Michigan, Ann Arbor; 4U Washington, Seattle; 5Northwestern, Chicago; 6Baylor, Dallas; 7RhoFed, Chapel Hill; 8NIAID, Bethesda.

    ITN030ST is a prospective randomized trial designed to determine the clinical benefit of early IS withdrawal in adult liver transplant (LT) recipients. Recipients did not…
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