Am J Transplant, Volume 16, Suppl 3 Archives - Page 64 of 180 - ATC Abstracts

2016 American Transplant Congress
Decellularized Rat Liver Scaffolds Support Multilineage Xenogenic and Heterogenic Cell Growth.
W. Hassanein, U. Dhru, J. Woodall, M. Uluer, A. Cimeno, D. Parsell, C. Rivera, S. Klepfer, C. Drachenberg, R. Barth, J. LaMattina.
University of Maryland School of Medicine, Baltimore, MD.
Background:Recent years have seen a proliferation of methods leading to successful organ decellularization. Nonetheless, the ability to reproducibly generate a robust recellularized construct remains challenging.…
2016 American Transplant Congress
HCK Is a Potential Mediator of Renal Fibrosis.
C. Wei,¹ M. Menon,¹ L. Li,² Z. Yi,¹ K. Keung,³ C. Woytovich,¹ I. Greene,¹ W. Zhang,¹ J. He,¹ B. Murphy.¹
¹Division of Nephrology, Icahn School of Medicine at Mount Sinai, New York, NY; ²Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY; ³Centre for Transplant and Renal Research, Westmead Millenium Institute, University of Sydney at Westmead Hospital, New South Wales, Australia.
Background: Renal fibrosis is the consequence of excessive accumulation of extracellular matrix that occurs in patients with chronic kidney disease (CKD) and in kidney transplant…
2016 American Transplant Congress
IL-10 Expression of In Vitro Activated B Cells as A Biomarker for B Cell Tolerance.
T. Oura, K. Hotta, K. Crisalli, B. Cosimi, T. Kawai.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Background: A significant role for regulatory B cell has been suggested in kidney transplant recipients who achieved operational tolerance while receiving conventional immunosuppression. We studied…
2016 American Transplant Congress
Infection-Related Mortality After Kidney Transplantation in the Current Era.
I. Helanterä,¹ S. Kinnunen,² P. Karhapää,² A. Juutilainen,² P. Finne.³
¹Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; ²Department of Medicine, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland; ³Department of Nephrology, Helsinki University Hospital, Helsinki, Finland.
A. Purpose: Infections are the most common non-cardiovascular causes of death after kidney transplantation. We analyzed in detail the current infection-related mortality among kidney transplant…
2016 American Transplant Congress
Outcomes of Liver Grafts from Donors with Very High Transaminases.
P. Martins, A. Rawson, P. Mahboub, B. Movahedi, N. Dolgin, I. Bruggenwirth, A. Bozorgzadeh.
Department of Surgery, Transplant Division, University of Massachusetts, Worcester, MA.
Introduction: Traditionally, elevation of transaminases has been broadly used as markers of hepatic ischemic injury and crucial parameters for liver graft assessment. We wanted to…
2016 American Transplant Congress
Reduced Incidence and Level of De Novo Donor-Specific Antibodies in Belatacept-Treated vs. Cyclosporine-Treated Patients: Final Results from BENEFIT.
R. Bray,¹ H. Gebel,¹ R. Townsend,² M. Polinsky,² L. Yang,² U. Meier-Kriesche,² C. Larsen.¹
¹Emory University, Atlanta, GA; ²Bristol-Myers Squibb, Lawrenceville, NJ.
Background: The presence of donor-specific antibodies (DSA) has been associated with an increased risk of antibody-mediated rejection and graft failure. Mean fluorescence intensity (MFI) is…
2016 American Transplant Congress
Factors Predicting Risk for Antibody-Mediated Rejection in Highly Sensitized Pediatric Renal Transplants.
I. Kim,¹ J. Choi,¹ A. Vo,¹ S. Louie,¹ J. Mirocha,² S. Jordan,¹ E. Kamil,¹ D. Puliyanda.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²Biostatistics Core, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: Antibody-mediated rejection (ABMR) is a concern in highly sensitized (HS) patients (pts) receiving renal transplant (tx). We have previously published that a donor specific…
2016 American Transplant Congress
Evaluating the Influence of Liver Donor and Recipient Race on Tacrolimus Dose Requirements.
J. Knorr, J. Vidal, V. Navarro, R. Zaki.
Einstein Medical Center, Philadelphia, PA.
Background: The majority of liver transplant recipients (LTR) receive tacrolimus (TAC) to prevent allograft rejection. Early establishment of therapeutic levels is imperative to efficacy. Several…
2016 American Transplant Congress
A Web-Based Survey of Academic Transplant Nephrologists in the U.S. on Relative Value Unit (RVU)-Based Productivity Assessment and Financial Compensation.
W. Chon,¹ M. Pavlakis,³ P. Witkowski,⁴ L.-X. Chen,¹ P. Kadambi.²
¹Medicine (Nephrology), University of Chicago, Chicago, IL; ²Medicine (Nephrology), Banner University Medical Center, Tucson, AZ; ³Medicine (Nephrology), Beth Israel Deaconess Medical Center, Boston, MA; ⁴Surgery (Transplant), University of Chicago, Chicago, IL.
Background: It is unknown how productivity of transplant nephrologists in the U.S. is measured. Methods: We conducted a web-based survey to ascertain the current RVU…
2016 American Transplant Congress
Effect of Conversion to mTOR Inhibition on Allograft Fibrosis in Pediatric Liver Transplantation.
R. Fischer,¹ S. Foster,² A. Kats,¹ W. Andrews,¹ R. Hendrickson,¹ J. Daniel.¹
¹Children's Mercy Hospital, Kansas City, MO; ²University of Kansas Medical Center, Kansas City, KS.
Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving liver allografts. These findings can lead to cirrhosis and graft failure. We compared two…