ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Antibody Titers as Predictors of Kidney Graft Outcomes.

    A. Gilbert,1 M. Zaheer,1 O. Timofeeva,2 S. Rosen-Bronson,2 M. Awwad,2 D. Li,2 M. Grafals,1 B. Javaid,1 P. Abrams,1 J. Verbesey,1 M. Cooper.1

    1Surgery, MedStar Georgetown Transplant Institute, Washington, DC; 2Pathology, MedStar Georgetown Transplant Institute, Washington, DC.

    PURPOSE: Development of de novo donor specific antibody (dnDSA) following kidney transplantation is not uncommon. As laboratory techniques advance, rates of dnDSA have increased. However,…
  • 2016 American Transplant Congress

    Kidney Transplant Induction Therapies: Risks of Death, Allograft Failure, Sepsis, and Cancer.

    N. Koyawala,1 J. Silber,2 P. Rosenbaum,1 R. Bloom,1 W. Wang,2 A. Hill,2 S. Nazarian,1 D. Sawinski,1 J. Trofe,1 M. Lim,1 J. Schold,3 P. Reese.1

    1University of Pennsylvania, Philadelphia; 2The Children's Hospital of Philadelphia, Philadelphia; 3Cleveland Clinic, Cleveland.

    Induction therapies are commonly used during kidney transplantation (~85% of transplants in 2012). Existing studies of induction therapy are limited by short follow-up and/or absence…
  • 2016 American Transplant Congress

    Antithymocyte (ATG) Dose Density in Renal Transplant Recipients (RTR) with Early Graft Dysfunction (EGD).

    S. Kuten, S. Patel, R. Knight, D. Nguyen, E. Graviss, H. Podder, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    The cumulative amount of ATG for induction may be given as consecutive (cDD) or intermittent day dosages (iDD). iDD allows for leukocyte or platelet recovery…
  • 2016 American Transplant Congress

    Projection versus Reality: KPSAM and KAS.

    S. Gustafson, A. Israni, J. Pyke, N. Salkowski, J. Snyder, B. Kasiske.

    Scientific Registry of Transplant Recipients, Minneapolis, MN.

    On December 4, 2014, the national kidney allocation system (KAS) was substantially revised. The decision to revise was based in part on results from the…
  • 2016 American Transplant Congress

    Alterations in Central Carbohydrate Metabolism in Porcine Liver Allografts Preserved with a Subnormothermic Machine Perfusion (SNMP) System.

    B. Banan, A. Cyr, R. Lopez, G. Michalopoulos, P. Fontes.

    University of Pittsburgh, Pittsburgh.

    Introduction: Combination of reduced temperature and oxygenation via machine perfusion during liver allograft preservation has the potential to induce profound effects on hepatocyte bioenergetics and…
  • 2016 American Transplant Congress

    Stem Cell-Mediated Regeneration of Ischemically Damaged Renal Allografts During Ex Vivo Warm Perfusion.

    L. Brasile,1 N. Henry,1 B. Stubenitsky.2

    1BREONICS Inc., Watervliet, NY; 2Plastic Surgery, University of Utrecht, Utrecht, Netherlands.

    Our goal is to address an unmet medical need by providing more kidneys for transplant. We asked 2 questions: Could a tissue-engineering platform be used…
  • 2016 American Transplant Congress

    Normothermic Perfusion of Livers Donated After Circulatory Death: A New Clinically Relevant Experimental Model.

    Y. Cao,1 H. Chew,1,2 K. Fernandez,1 L. Gao,1 J. Villanueva,1 M. Hicks,1 P. Macdonald,1,2 K. Dhital,1,2 H. Pleass.3

    1Victor Chang Cardiac Research Institute, Sydney, NSW, Australia; 2Cardiac Transplant Unit, St. Vincent's Hospital, Sydney, NSW, Australia; 3The Department of Surgery, Westmead Hospital, Sydney, NSW, Australia.

    Aim. Transplantation using livers donation after circulatory death (DCD) is associated with worse outcomes compared to using donation after brain death (DBD). Considerable research resources…
  • 2016 American Transplant Congress

    Robotic-Assisted Laparoscopic Donor Nephrectomy with Transvaginal Extraction of the Kidney.

    C. Champy,1 L. Salomon,1 I. Cholley,1 A. Hoznek,1 R. Yiou,1 D. Vordos,1 P. Grimbert,2 P. Lang,2 A. De La Taille.1

    1Urology Department - INSERM U955, Henri Mondor, Créteil, France; 2Nephrology Department, Henri Mondor, Créteil, France.

    Minimally invasive surgery aims to the reduction of complications, pain and scars. Thus, vaginal extraction of the donor's kidney has been reported as an option…
  • 2016 American Transplant Congress

    Pre-Emptive Kidney Transplantation with Living- Donor and Concomitant Unilateral Nephrectomy in Patients with Autosomal-Dominant Polycystic Kidney Disease: A Safe Strategy?

    C. Michel,1 F. Audenet,1 M. Ariane,1 C. Legendre,2 D. Joly,2 A. Méjean,1 M.-O. Timsit.1

    1Urology, Hôpital Européen Georges Pompidou, Paris, France; 2Nephrology and Transplantation, Hôpital Necker, Paris, France.

    Objectives. Because the timing of the nephrectomy still remains unclear, we studied the complications and outcomes of unilateral nephrectomy and concomitant pre-emptive kidney transplant with…
  • 2016 American Transplant Congress

    Predictive Model of Delayed Graft Function in Machine Perfused Kidney Transplantation: Model Validation Using Decision Curve Analysis.

    K. Ravindra,1 S. Sanoff,1 D. Vikraman,1 U. Patel,1 M. Ellis,1 E. Squires,2 D. Sudan,1 W. Irish.1

    1Surgery, Duke University, Durham, NC; 2Half Moon Bay, Raleigh.

    Introduction: Predictive model for delayed graft function (DGF) was developed (Am J Transpl 2010; 10: 2279–86)excluding organs that were machine perfused (MP). Currently, approximately 50%…
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