Am J Transplant, Volume 16, Suppl 3 Archives - Page 56 of 180 - ATC Abstracts

2016 American Transplant Congress
Clinical Significance of Solitary Pulmonary Nodules in Liver Transplant Recipients with Hepatocellular Carcinoma.
O. Serrano,¹ A. Bangdiwala,² D. Vock,² V. Kirchner,¹ K. Yadav,¹ A. Pugalendhi,¹ E. Minja,¹ T. Dunn,¹ E. Finger,¹ A. Matas,¹ R. Kandaswamy,¹ W. Payne,¹ T. Pruett,¹ S. Chinnakotla.¹
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics and Bioinformatics Core, Masonic Cancer Center, Minneapolis, MN; ³Biostatistics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: Currently, there are no guidelines for the management of solitary pulmonary nodules (SPN) in hepatocellular carcinoma (HCC) patients being evaluated for liver transplantation (LT).…
2016 American Transplant Congress
Pre-Transplant Intra-Arterial Liver Directed Therapy Does Not Increase the Risk of Hepatic Arterial Misadventures in Liver Transplantation.
J. Kallini,² A. Gabr,² R. Salem,² R. Lewandowski,² T. Baker.¹
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²Division of Interventional Oncology, Northwestern University, Chicago, IL.
Background: Pretransplant liver directed therapy has emerged as standard of care for patients with end stage liver disease complicated by unresectable hepatocellular cancer. The aim…
2016 American Transplant Congress
Long-Term Outcomes After Splenectomy for Small-for-Size Syndrome in Live Donor Liver Transplantation.
M. Dib, N. Goldaracena, A. Barbas, M. Marquez, G. Sapisochin, C. Beriault, N. Selzner, I. McGilvray, E. Renner, P. Greig, L. Lilly, A. Ghanekar, M. Cattral, M. Selzner, D. Grant.
Transplantation, Toronto General Hospital, Toronto, ON, Canada.
Introduction: The use of lower volume liver grafts has the potential to expand the donor pool in adult-to-adult live donor liver transplantation (LDLT), but is…
2016 American Transplant Congress
Metabolomic Profiling of Individuals with Failing Kidney Allograft.
R. Bassi,^1,2 M. Niewczas,³ L. Biancone,⁵ S. Bussolino,⁵ A. Lin,⁴ A. Chandraker,⁶ P. Fiorina.^1,2
¹Nephrology, Boston Children's Hospital, Boston; ²Transplant Medicine, IRCCS San Raffaele Hospital, Milan, Italy; ³Genetics and Epidemiology, Joslin Diabetes Center, Boston; ⁴Radiology, Brigham and Women's Hospital, Boston; ⁵Nephrology and Transplantation, San Giovanni Battista Hospital, Turin, Italy; ⁶Transplantation Research Center, Brigham and Women's Hospital, Boston.
Alteration of certain metabolites may play a role in the pathophysiology of renal allograft disease. To explore metabolome abnormalities in individuals with a failing kidney…
2016 American Transplant Congress
The Effect of Everolimus and Tacrolimus Exposure Levels on Renal Histology Parameters 6 Months Post-Transplantation.
S. Yilmaz,¹ D. Shaffer,² Y. Qazi,³ K. McCague,⁴ D. Patel,⁴ V. Peddi,⁵ F. Vincenti.⁶
¹University of Calgary, Calgary, Canada; ²Vanderbilt University, Nashville; ³University of Southern California, Los Angeles; ⁴Novartis Pharmaceuticals Corporation, East Hanover; ⁵California Pacific Medical Center, San Francisco; ⁶University of California San Francisco, San Francisco.
We examined renal histology scores in patients with different exposure levels of everolimus (EVR) and tacrolimus (TAC) over 6 months.Renal transplant patients (N=613) were randomized…
2016 American Transplant Congress
Characteristics Independently Associated with Kidney Candidates Having CPRA of 99-100%.
A. Kucheryavaya, D. Klassen, D. Stewart.
UNOS, Richmond, VA.
Background: The new Kidney Allocation System (KAS) implemented on 12/4/14 included an increased allocation priority for candidates with CPRA 99-100%. On 11/30/14, just days prior…
2016 American Transplant Congress
Correlation of the Shear Wave Elastography with Renal Function in Kidney Transplant Recipients: A Proof of Concept Study.
J. Dosal-Bañuelos, A. Flores-Mendoza, L. Morales-Buenrostro, M. Díaz-Zamudio.
Radiology and Nephrology, National Institute of Medical Sciences and Nutrition SZ, México, Distrito Federal, Mexico.
Background: Non-invasive biomarker for kidney allograft fibrosis is needed. Shear wave elastography is a relatively new technique to assess tissue stiffness. Graft rejection and chronic…
2016 American Transplant Congress
Number of Bacterial Isolates and Resistance Increases Mortality Risk in Intestinal Transplant Patients.
D. Patel, H. Shah, T. Schiano, J. Moon, K. Iyer, S. Huprikar.
Icahn School of Medicine at Mount Sinai, New York.
BackgroundInfection is the most common complication in intestinal transplant (IT) recipients. Data regarding the impact of infections on outcomes following IT is limited.MethodsThis is a…
2016 American Transplant Congress
Donor Sharpin Expression Modulates TNFα Mediated Inflammation and Cardiac Allograft Rejection in Mice.
R. Ang,¹ P. Heeger,² A. Ting.¹
¹Immunology Institute, Icahn School of Medicine at Mount Sinai, New York City, NY; ²Center for Translational Transplant Research, Icahn School of Medicine at Mount Sinai, New York City, NY.
Increased systemic TNFα levels correlate with transplant rejection and severity of GVHD, and TNFα blockade can prolong graft survival and reduce severity of GVHD. These…
2016 American Transplant Congress
CMV-Accelerated Cardiac Allograft Rejection Is Associated with Dysregulation of Sphingolipid Metabolomics.
J. Burg,¹ T. Andoh,² N. Haese,² C. Kreklywich,² K. Watters,³ T. Metz,³ S. Orloff,¹ D. Streblow.²
¹Abdominal Organ Transplantation, OHSU, Portland, OR; ²VGTI, OHSU, Portland, OR; ³Biological Sciences Division, PNNL, Richland, WA.
PurposeCytomegalovirus (CMV) infection accelerates transplant vascular sclerosis (TVS) and chronic rejection (CR) in solid organ transplants. Sphingolipid metabolism plays an immunomodulatory role in transplant rejection,…