ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Evaluation of the Utilization of Filgrastim in Kidney Transplant Recipients.

    T. Poon,1 C. Guerra.2

    1Pharmacy, Long Island University, Brooklyn, NY; 2Pharmacy, SUNY Downstate Medical Center, Brooklyn, NY.

    Purpose: Granulocyte colony-stimulating factors (G-CSF), such as filgrastim, stimulate the production, proliferation, and differentiation of neutrophils and are indicated for the treatment of neutropenia in…
  • 2016 American Transplant Congress

    Hepatitis C Eradication with Sofosbuvir Based Regimens Leads to Significant Metabolic Changes in Post Orthotopic Liver Transplant Patients.

    A. Morales,1 M. Singla,2 H. Greenwald,1 S. Robertazzi,1 C. Rodigas,1 V. Washington,1 R. Satoskar,1 C. Smith.1

    1MedStar Transplant Institute, Georgetown University Hospital, Washington, DC; 2Gastroenterology Service, Walter Reed National Military Medical Center, Bethesda, MD.

    The purpose of this study was to assess the effect of hepatitis C virus (HCV) eradication with sofosbuvir based regimens on glycemic and lipid control…
  • 2016 American Transplant Congress

    Pulse Wave Velocity Amongst African-American Kidney Transplant Recipients Randomized to Once-Daily MeltDose Tacrolimus Tablets (Envarsus XR) vs. Traditional Twice-Daily Tacrolimus Capsules: Exploratory Results from a Phase III Trial.

    J. Trofe-Clark,1,2 R. Townsend,2 R. Neubauer,2 M. Lim,2 L. Callahan,3 R. Bloom.2

    1Pharmacy Services, Hospital of the University of Pennsylvania, Philadelphia, PA; 2Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; 3Veloxis Pharmaceuticals, Edison, NJ.

    Cardiovascular (CV) death is a leading cause of death in kidney transplant recipients (KTR). Increased aortic arterial stiffness is strongly associated with the development of…
  • 2016 American Transplant Congress

    Impact of Mixed Xenogeneic Porcine Hematopoietic Chimerism on Human NK Cell Recognition in a Humanized Mouse Model.

    H. Li,1 P. Vishwasrao,1,2 M. Holzl,1 S. Chen,1 G. Choi,2,3 G. Zhao,1 M. Sykes.1

    1Columbia Center for Translational Immunology, Columbia University, New York, NY; 2Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; 3Department of Hematology, University Medical Center Groningen, Groningen, Netherlands.

    Xenotransplantation is a potential solution for the shortage of organs for transplantation. However, potent xenograft rejection responses present a formidable barrier. Mixed xenogeneic hematopoietic chimerism…
  • 2016 American Transplant Congress

    Increased Waitlist Death and Removal in Pediatric Liver Transplant Recipients Denied Exception Requests.

    H. Braun,3 J. Dodge,2 S. Rhee,1 J. Roberts,2 E. Perito.1

    1Pediatrics, UCSF, San Francisco, CA; 2Surgery, UCSF, San Francisco, CA; 3School of Medicine, UCSF, San Francisco, CA.

    Purpose: Over 30% of children listed for liver transplant (LT) have exceptions filed to increase their PELD/MELD. Non-standard exception requests (NSER) are granted by regional…
  • 2016 American Transplant Congress

    Transplant Education Increases Wait-Listing Rates in Dialysis Centers with Supportive Administration and Knowledgeable Staff.

    A. Waterman,1 J. Peipert,1 H. Xiao,2 C. Goalby,1 K. Lentine.2

    1UCLA, Los Angeles, CA; 2St. Louis Univ., St. Louis, MO.

    While educating dialysis patients about transplant increases its pursuit and receipt, there is variation in educational practices that affects wait-listing rates. There are also dialysis…
  • 2016 American Transplant Congress

    Impact of Preoperative Body Composition on Outcomes After Living Donor Liver Transplantation.

    Y. Hamaguchi, T. Kaido, A. Kobayashi, S. Okumura, S. Yagi, H. Okajima, S. Uemoto.

    Division of Hepato-Biliary-Pancreatic and Transplant Surgery, Department of Surgery, Kyoto University, Kyoto, Japan.

    Background: Skeletal muscle depletion has been shown to be an independent predictor of lower overall survival in various diseases. In surgical fields, however, the significance…
  • 2016 American Transplant Congress

    Impact of Early Acute Rejection (AR) on Pancreas Transplant (PT) Outcomes.

    V. Kirchner, T. Dunn, A. Kukla, R. Kandaswamy, E. Finger.

    University of Minnesota, Minneapolis.

    Background: The role of early AR in long-term PT outcomes remains unclear. Despite reported high rate of AR (up to 40% in PTA), graft survival…
  • 2016 American Transplant Congress

    Associations Between Deceased-Donor Urine MCP-1 and Kidney Transplant Outcomes.

    S. Mansour,1 J. Puthumana,1 P. Reese,2 I. Hall,1 M. Doshi,3 F. Weng,4 B. Schröppel,5 H. Thiessen-Philbrook,1,6 M. Bimali,1 C. Parikh.1

    1Nephrology, Yale University School of Medicine, New Haven, CT; 2Renal-Electrolyte and Hypertension, University of Pennsylvania, Philadelphia, PA; 3Wayne State University, Detroit, MI; 4Saint Barnabas Medical Center, Livingston, NJ; 5Nephrology, University Hospital, Ulm, Germany; 6Nephrology, Western University, London, ON, Canada.

    Current assessments of deceased donor kidneys lack precision in predicting recipient graft function. Mouse models have demonstrated that monocyte chemoattractant protein-1 (MCP-1) has a pivotal…
  • 2016 American Transplant Congress

    Does Post-Transplant Adherence Come at a Cost?

    K. Yadav, T. Nevins, D. Vock, W. Thomas, W. Robiner, A. Matas.

    University of Minnesota, Minneapolis, MN.

    Background: It is well documented that organ transplant (tx)recipients have an increased incidence of cancer including virus associated cancers like lymphoma. Our objective was to…
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