Am J Transplant, Volume 16, Suppl 3 Archives - Page 46 of 180 - ATC Abstracts

2016 American Transplant Congress
Regression of Asymptomatic Cardiomyopathy and Clinical Outcome of Renal Transplant Recipients: Long-Term Extension of Two Randomized Controlled Trials.
E. Paoletti, D. Bellino, L. Marsano, R. Russo, F. Masarino, G. Garibotto.
Nephrology, Dialysis, and Transplantation, University of Genoa, Genoa, Italy.
Background Asymptomatic left ventricular hypertrophy (LVH) is highly prevalent and associated with adverse outcome in renal transplant recipients (RTRs). Nonetheless, there are currently no available…
2016 American Transplant Congress
Heparanase: A New Factor Involved in the Pro-Fibrotic Renal Biological Machinery Activated by the Ischemia/Reperfusion (I/R) Injury.
G. Zaza,¹ V. Masola,¹ G. Gambaro,² M. Onisto,³ G. Bellin,¹ I. Vlodavsky,⁴ Z. Abassi,⁵ A. Lupo.¹
¹Renal Unit, Department of Medicine, University of Verona, Verona, Italy; ²Division of Nephrology and Dialysis, Columbus-Gemelli Hospital Catholic University, Rome, Italy; ³Department of Biomedical Sciences, University of Padova, Padova, Italy; ⁴Cancer and Vascular Biology Research Center, Rappapor Faculty of Medicine, Technion, Haifa, Israel, Italy; ⁵Department of Physiology and Biophysics, Rappaport Faculty of Medicine, Technion, Haifa, Israel, Italy.
Ischemia/reperfusion (I/R) is an important cause of acute renal failure and delayed graft function, and it may induce chronic renal damage by activating epithelial to…
2016 American Transplant Congress
Interaction Between Kidney Tissue Proteome and Humoral Immunity in Antibody Mediated Rejection.
A. Konvalinka,¹ A. Chruscinski,² S. Kim,¹ K. Tinckam,¹ I. Jurisica,³ R. John.⁴
¹Medicine/Division of Nephrology, Toronto General Hospital, Toronto, ON, Canada; ²Medicine/Division of Cardiology, Toronto General Hospital, Toronto, ON, Canada; ³Medical Biophysics and Computational Science, University of Toronto, Toronto, ON, Canada; ⁴Pathology, Toronto General Hospital, Toronto, ON, Canada.
PURPOSE: Antibody-mediated rejection (AMR) is caused by antibodies against human leukocyte antigens (HLA) on graft endothelium, and non-HLA antibodies that target endothelial and epithelial proteins.…
2016 American Transplant Congress
Resveratrol Effectively Suppress Th17 Associated Allo-Immune Responses by the Modulation of AMPK/mTOR Pathway.
B. Chung, K. Doh, J.-W. Min, K. Kim, B.-M. Kim, M.-L. Cho, C. Yang.
Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
The aim of this study is to investigate the effect of resveratrol on Th17 allo-immune responses under tacrolimus (Tac)-based immune suppression. First, we investigated the…
2016 American Transplant Congress
HLA Antibody Clonality and Epitopes Dictate Complement Activation.
K. Thomas,¹ N. Valenzuela,¹ A. Mulder,² E. Reed.¹
¹Pathology and Laboratory Medicine, UCLA, Los Angeles, CA; ²Leiden University Medical Center, Leiden, Netherlands.
Background: Alloimmunization results in production of polyclonal donor specific antibodies (DSA) against human leukocyte antigens (HLA), which mediate endothelial cell activation, leukocyte recruitment, and complement…
2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
I. Moinuddin, T. Taber, M. Yaqub, D. Mishler, O. Adebiyi, J. Chen, M. Goble, J. Powelson, J. Fridell, A. Sharfuddin.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…
2016 American Transplant Congress
Validation of SUITO Index and C-Peptide/Glucose Creatinine Ratio as Convenient Tools for the Evaluation of the Short and Long-Term Islet Allograft Function.
J. Gołębiewska,¹ J. Solomina,² S. Matosz,² C. Thomas,³ L. Schenck,² K. Golab,² W. Chon,³ S. Ramachandran,² M. Tibudan,² A. Dębska-ŚLizień,¹ B. Rutkowski,¹ P. Witkowski.²
¹Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland; ²Department of Surgery, University of Chicago, Chicago, IL; ³Department of Medicine, University of Chicago, Chicago, IL.
Background: Mixed Meal Tolerance Test (MMTT) together with the beta-score are standard tools to evaluate beta-cell function after islet transplantation but utilization of the test…
2016 American Transplant Congress
The In Vivo Non-Invasive Long-Term Functional Assessment of Neuronal Regeneration in Vascularized Composite Allotransplantation.
C.-J. Wen,^1,2 C.-H. Lin,¹ S.-L. Peng,^3,4 F.-N. Wang,³ L.-Y. Huang,³ H.-Y. Cheng,¹ H.-H. Hsu,¹ X.-T. Huang,¹ C.-H. Lin,¹ F.-C. Wei.¹
¹Center for Vascularized Composite Allotransplantation, Chang Gung Medical Foundation, Taoyuan, Taiwan; ²Department of Medicine, Chang Gung University, Taoyuan, Taiwan; ³Department of Biomedical Engineering and Environmental Sciences, Tsing Hua University, Hsinchu, Taiwan; ⁴Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.
The neuronal regeneration is a key issue of vascularized composite allotransplantation (VCA).As for the generally used functional observations, behavior testing or invasive functional inspection (e.g.…
2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
A. DeMers, R. Forbes, D. Moore, K. Smith, D. Shaffer.
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…
2016 American Transplant Congress
Long Term Follow Up of Kidney Donors with Asymptomatic Renal Stones.
D. Serur,¹ M. Charlton,² K. Juluru,³ G. Salama,³ E. LoCastro,³ G. Bretzlaff,² C. Hartono.¹
¹Nephrology/Rogosin, New York Presbyterian Weill Cornell, New York, NY; ²Kidney and Pancreas Transplantation, New York Presbyterian Weill Cornell, New York, NY; ³Radiology, New York Presbyterian Weill Cornell, New York, NY.
BACKGROUND:Kidney stones are often found incidentally in potential renal donors and there is a concern that they may become symptomatic and cause damage in the…