ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Kidney Transplant Recipient Adherence Measured by Proportion of Days Covered Is Associated with Late Biopsy Proven Acute Rejection.

    B. Hofmeyer, K. Look, J. Fose, A. Pulvermacher, A. Djamali, D. Hager.

    UW Health, Madison, WI.

    While medication non-adherence is a known risk factor for late “biopsy proven acute rejection (BPAR),” the Pharmacy Quality Alliance definition of “proportion of days covered…
  • 2016 American Transplant Congress

    Comparison of Early Engraftment Immunobiology of Xenoislets and Alloislets in a Dual Transplant Model.

    K. Samy,1 B. Martin,2 M. Song,1 B. Collins,1 E. Gall,1 J. Cano,2 A. Farris,2 F. Leopardi,1 A. Kirk.1,2

    1Department of Surgery, Duke University Medical Center, Durham, NC; 2Emory University, Atlanta, GA.

    Purpose: Successful implementation of neonatal porcine islet (NPI) xenotransplantation requires an understanding of the xenospecific immune elements influencing engraftment. To elucidate these early xenospecific processes,…
  • 2016 American Transplant Congress

    Outcomes of Isolated Pediatric Small Intestine Transplants Using Vascular Homografts.

    Y. Kwon, N. Llore, R. Girlanda, K. Etesami, C. Desai, C. Matsumoto, T. Fishbein.

    MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC.

    Background/aim: Pediatric intestinal transplantation has changed recently with more isolated small intestine transplants being performed in small children instead of combined liver-intestine transplants. Consequently, surgical…
  • 2016 American Transplant Congress

    Incidence of Depression Following Live Kidney Donation.

    J. Leanza,1 S. Anjum,1 L. Fahmy,1 S. Bae,1 R. Reed,2 J. Locke,2 A. Massie,1 D. Segev.1

    1JHU, Baltimore; 2UAB, Birmingham.

    Post-donation depression (PDD) and regret (PDR) remain poorly characterized for live kidney donors. Individuals who develop kidney-related medical conditions after donating may have higher odds…
  • 2016 American Transplant Congress

    Durable Clinical and Immunologic Advantage of Living Donor Liver Transplantation (LDLT) in Children.

    E. Przybyszewski,1 S. Lobritto,1 M. Martinez,1 J. Vittorio,1 A. Fox,1 B. Samstein,2 T. Kato,1 A. Griesemer,1 J. Emond.1

    1Columbia University Medical Center, New York, NY; 2Weill Cornell Medical College, New York, NY.

    Purpose:Despite good results, only 10% of liver transplants in children in the US are from living donors. In addition to optimal timing and graft quality,…
  • 2016 American Transplant Congress

    Potent Induction Therapy Improves Graft Outcome in Younger Pancreas Transplant Recipients (<30 Years of Age).

    A. Gruessner, V. Whittaker, S. Narsipur, V. Aggarwal, C. Hubbel, R. Gruessner.

    SUNY Upstate Medical University, Syracuse, NY.

    Purpose: Pancreas transplants (tx) are increasingly performed in older patients with type 1 diabetes mellitus. This trend may be explained by the significantly higher immunologic…
  • 2016 American Transplant Congress

    The First Impressions: A Study in Pre and Post-Implantation Renal Grafts for Early Detection Markers of Delayed Graft Function and Recovery.

    S. Bontha,1 L. Suh,1 P. Dormish,1 R. Gehrau,1 E. Rhone,1 L. Gallon,3 A. King,2 C. Dumur,2 D. Maluf,1 V. Mas.1

    1UVA, Charlottesville; 2VCU, Charlottesville; 3Northwestern University, Chicago.

    Background: Delayed graft function (DGF) is mainly a consequence of ischemia and reperfusion injury (IRI) resulting in acute tubular necrosis. The degree of IRI is…
  • 2016 American Transplant Congress

    Variation in Co-Medication Use According to Kidney Transplant Immunosuppressive Regimen: Application of Integrated Registry and Pharmacy Claims Data.

    K. Lentine,1 A. Naik,2 M. Schnitzler,1 D. Axelrod,3 J. Chen,1 D. Brennan,4 D. Segev,5 B. Kasiske,6 H. Randall,1 V. Dharnidharka.4

    1Saint Louis Univ, St. Louis; 2Univ Michigan, Detroit; 3Dartmouth Univ, Hanover; 4Washington Univ, St. Louis; 5Johns Hopkins Univ, Baltimore; 6Univ Minnesota, Minneapolis.

    Background: While modern immunosuppressive therapies (ISx) have substantially reduced acute rejection, ISx medications have many side effects, and transplant recipients must take an array of…
  • 2016 American Transplant Congress

    Early Post-Transplant Patient, Graft Survival and Rejection Rates Under KAS.

    A. Kucheryavaya, D. Stewart, D. Klassen.

    UNOS, Richmond.

    Background: KAS, implemented on 12/4/14, resulted in changes in recipient, donor/recipient and tx characteristics that have the potential to affect post-tx outcomes.Data and Methods: We…
  • 2016 American Transplant Congress

    Primary Outcome of iWITH: A Multi-Center Clinical Trial of Complete Immunosuppression Withdrawal (ISW) in Stable Pediatric Liver Transplant (LT) Recipients.

    S. Feng,1 J. Bucuvalas,2 A. Demetris,3 K. Spain,4 S. Kanaparthi,5 J. Magee,6 G. Mazariegos,3 The iWITH Investigators.7

    1UCSF, San Francisco; 2CCHMC, Cincinnati; 3U Pitt, Pittsburgh; 4Rho, Chapel Hill; 5ITN, Bethesda; 6U Mich, Ann Arbor; 7NIAID/NIDDK/ITN, Bethesda.

    AIM: Test the hypothesis that a selected cohort of pediatric LT recipients can safely undergo complete ISW followed by assessment for operational tolerance (OT)METHODS: 88…
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