Am J Transplant, Volume 16, Suppl 3 Archives - Page 3 of 180 - ATC Abstracts

2016 American Transplant Congress
Donor HLA Specific IgM Antibody Measured on Day 14 Post-Transplantation Predicts Poor Graft Survival in HLA-Incompatible Renal Transplantation.
A. Babu, A. Androeu, S. Daga, R. Higgins, D. Mitchell, D. Briggs, N. Khovanova, N. Krishnan.
Renal Medicine, University Hospital Coventry and Warwickshire, Coventry, West Midlands, United Kingdom; Life Sciences, University of Warwick, Coventry, West Midlands, United Kingdom; Histocompatibility and Immunogenetics, NHS Blood and Transplant, Birmingham, West Midlands, United Kingdom; School of Engineering, University of Warwick, Coventry, United Kingdom.
Introduction: Role of IgG antibodies against donor human leucocyte antigens (HLA) is established in renal transplant monitoring. Role of IgM donor HLA specific antibodies (DSA)…
2016 American Transplant Congress
Age Gap Analysis Between Live Donor and Recipients in Kidney Transplantation: Opportunities to Improve Voluntary Exchange Programs and Kidney Paired Donation.
J. Rodriguez,¹ A. Patel,² M. Goggins.²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI; ²Transplant Institute, Henry Ford Hospital, Detroit, MI; ³Transplant Institute, Henry Ford Hospital, Detroit, MI.
Graft survival(GS) perception is that, with a smaller age gap between the donor(D) and recipient(R), better the outcome. It is unclear if there is an…
2016 American Transplant Congress
Post-Transplant Reduction of Long Lived Plasma Cells from Peripheral Circulation Is Associated with Acute Rejection in Kidney Transplant Recipients.
R. Minz,¹ R. Dhital,² M. Minz,² R. Nada,³ A. Sharma,² S. Singh,² D. Kenwar.²
¹Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India; ²Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India; ³Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Introduction:Plasma cells (PC) are usually defined functionally as antibody secreting cells (ASC). Depending upon their life span, they could either be short lived or long…
2016 American Transplant Congress
Urinary Expression of miRNA-155, miRNA-210, miRNA-142 and CXCL-10 Production Predicts the Risk of Acute Rejection and Graft Outcome in Renal Transplant Recipients.
O. Millan,¹ K. Budde,² C. Sommerer,³ I. Aliart,¹ O. Rissling,² B. Bardaji,⁴ M. Matz,² M. Zeier,³ I. Silva,⁴ L. Guirado,⁴ M. Brunet.¹
¹Pharmacology Laboratory, CDB, IDIBAPS, Hospital Clinic Barcelona, Barcelona University, Barcelona, Spain; ²Medizinische Klinik mit Schwerpunkt Nephrologie, Charité Universitätsmedizin, Berlin, Germany; ³Department of Nephrology, University Hospital Heidelberg and Mannheim, Heidelberg, Germany; ⁴Renal Transplant Unit, Fundació Puigvert, Barcelona, Spain.
MicroRNAs (miRs) have been reported to play a role in immune system response. The results of several clinical trials have suggested that these molecules might…
2016 American Transplant Congress
Which Is the Predictable Value of Post-Transplant HCC Recurrence Between Tumor-Related Factors at the Initial Diagnosis and the Transplantation?
J. Lee,^1,2 J. Lee,¹ J. Lee,³ S. Song,¹ J. Lee,¹ S.-K. Kwon,¹ M. Ju,^1,2 M. Kim,^1,2 G. Choi,^1,2 J. Choi,^1,2 S. Kim,^1,2 D. Joo.^1,2
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; ²Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.
Background: Milan criteria is best options to decide whether patients with HCC underwent liver transplantation. However, Milan Criteria is not including values at time of…
2016 American Transplant Congress
Living Donor Liver Transplantation for Sick Patients with MELD Score ≥ 35.
R.-S. Soong,¹ Y.-C. Wang,¹ C.-H. Cheng,¹ T.-H. Wu,¹ C.-F. Lee,¹ T.-J. Wu,¹ H.-S. Chou,¹ K.-M. Chan,¹ C.-S. Lee,² W.-C. Lee.¹
¹Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Taoyuan, Taiwan; ²Hepatology, Chang-Gung Memorial Hospital, Taoyuan, Taiwan.
Background: The liver transplant candidates with MELD score ≥ 35 were very sick and with high mortality without liver transplantation. All these patients are in…
2016 American Transplant Congress
Torque Teno Virus – Inverse Association with Late Silent Antibody Mediated Kidney Allograft Rejection.
G. Bond,¹ M. Schiemann,¹ F. Eskandary,¹ H. Herkner,² E. Puchhammer,³ R. Oberbauer,¹ G. Böhmig.¹
¹Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ²Emergency Medicine, Medical University of Vienna, Vienna, Austria; ³Virology, Medical University of Vienna, Vienna, Austria.
Clinical Problem and hypothesis: Antibody mediated rejection (ABMR) is a cardinal cause of late graft failure after kidney transplantation (KTX). A promising predictive diagnostic tool…
2016 American Transplant Congress
Do Highly Sensitized Recipients Benefit from the Immunological Advantages of Zero Mismatched (0MM) Deceased Donors (DD) Kidney Allografts?
N. Elfadawy,¹ S. Flechner,² J. Schold.²
¹Internal Medicine, Case Western Reserve University, Cleveland, OH; ²Glickman urological and kidney institute, Cleveland Clinic, Cleveland, OH.
HLA 0MM DD transplants have superior outcomes compared with outcomes for grafts with ≥1 HLA mismatches, but when past reports analyzed 0MM outcomes in DD,…
2016 American Transplant Congress
Gut Dysbiosis and Metabolic Disorders in Kidney Transplant Recipients.
M. Lecronier,¹ P. Tashk,¹ J. Aron-Wisnewsky,^2,3,4 E. Denamur,¹ O. Tenaillon,¹ B. Barrou,^4,5 J. Tourret.^1,4,5
¹IAME, UMR 1137, INSERM, Paris, France; ²Institute of Cardiometabolism and Nutrition, ICAN, Service de Nutrition, GH Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France; ³UMR_S U1166, équipe NutriOmics, INSERM, Paris, France; ⁴Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; ⁵AP-HP, Département d'Urologie, Néphrologie et Transplantation, GH Pitié-Salpêtrière Charles Foix, Paris, France.
IntroductionGut microbiota modifications (dysbiosis) have been observed in obese and/or diabetic patients. Kidney transplant recipients (KTR) are particularly exposed to the development of metabolic disorders,…
2016 American Transplant Congress
Serum Inflammatory Biomarkers in Kidney Transplant Recipients and Renal Donors.
J. Ramirez,¹ E. Cuevas,¹ J. Furuzawa,² L. Morales-Buenrostro,³ M. Lopez-Cervantes,² J. Alberu.¹
¹Transplantation, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ²Immunology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ³Nephrology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ⁴Medicine School, UNAM, Mexico City, Mexico.
Kidney transplant recipients (KTR) have an increased risk for cardiovascular events, graft failure, and death. It is unknown whether serum inflammatory biomarkers correlate with eGFR…