ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Necroptosis Is Involved in CD4+ T-Cell Mediated Microvascular Endothelial Cell Death and Chronic Cardiac Allograft Rejection.

    C. Kwok,1,2 N. Montwill,1,2 A. Pavlosky,1,2 A. Haig,2 X.-Y. Huang,1 A. Jevnikar,1,3 Z.-X. Zhang.1,2,3

    1Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, Canada; 2Department of Pathology and Laboratory Medicine, Western University, London, Canada; 3Department of Medicine, Western University, London, Canada.

    Heart transplantation is potentially the only viable option for patients with end-stage heart failure. Despite advances in immunosuppressive therapies, cardiac allograft chronic rejection is a…
  • 2016 American Transplant Congress

    Acquired Down-Regulation of B Cell Function Induced by Donor Blood Group Antigens After ABO-Incompatible Kidney Transplantation.

    M. Tasaki,1 K. Saito,1 Y. Nakagawa,1 N. Imai,2 T. Aoki,3 M. Kamimura,3 K. Takahashi,1 Y. Tomita.1

    1Division of Urology, Department of Regenerative & Transplant Medicine, Niigata Graduate School of Medical and Dental Sciences, Niigata, Japan; 2Division of Clinical Nephrology and Rheumatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan; 3Division of Transfusion Medicine and Regenerative Medicine Bioscience Medical Center, Niigata University Medical and Dental Hospital, Niigata, Japan.

    Background: The long-term of B cell immunobiology against donor blood group antigen has not been elucidated in ABO incompatible kidney transplantation (ABOi KTx).Methods: The antibody…
  • 2016 American Transplant Congress

    Analysis of a Large Single-Center Cohort of Renal Transplant Recipients with Histoplasmosis.

    M. Mashayekhi, A. Langone.

    Internal Medicine, Vanderbilt University Medical Center, Nashville, TN.

    The dimorphic fungus Histoplasma capsulatum is endemic along the Ohio and Mississippi River Valleys and can cause clinically significant disease in those with impaired cellular…
  • 2016 American Transplant Congress

    In Situ Aortic Flush with Lactated Ringer's (LR) Solution During Donation After Brain Death (DBD) Organ Procurement Provides Similar Outcomes and Significantly Decreases Costs in Kidney and Liver Transplantation Compared to Standard Preservation Solutions.

    S. Rudich, P. Lange.

    Medical Division, Gift of Life Michigan, Ann Arbor, MI.

    PURPOSE: To determine if LR, when used as the initial in situ aortic flush during DBD renal and hepatic procurement, was safe, effective, and non-inferior…
  • 2016 American Transplant Congress

    Long-Term Outcomes in Epstein-Barr Virus (EBV)-Positive Patients Receiving Belatacept (Bela) or Cyclosporine (CsA) in BENEFIT-EXT.

    S. Florman,1 J. Medina Pestana,2 M. del C Rial,3 L. Rostaing,4 D. Kuypers,5 A. Matas,6 T. Wekerle,7 J. Grinyó,8 U. Meier-Kriesche,9 M. Polinsky,9 H. Zhao,9 A. Durrbach.10

    1Mount Sinai Med Ctr, New York; 2Hosp do Rim, Sao Paulo, Brazil; 3Instituto de Nefrologia, Buenos Aires, Argentina; 4Univ Hosp, Toulouse, France; 5Univ Hosp Leuven, Leuven, Belgium; 6Univ of Minnesota, Minneaopolis; 7Med Univ of Vienna, Vienna, Austria; 8Univ Hosp Bellvitge, Barcelona, Spain; 9BMS, Lawrenceville; 10Univ Hôpital of Bicêtre, Le Kremlin-Bicêtre, France.

    At 7 yrs post transplant in BENEFIT-EXT (NCT00114777), bela-treated pts had similar graft survival and improved renal function vs CsA-treated pts. Bela is indicated for…
  • 2016 American Transplant Congress

    Renal Outcomes of Pediatric Kidney Transplant Recipients Following a Previous Solid Organ Transplantation.

    G. Hamdani,1 B. Zhang,2 J. Goebel,3 E. Nehus.1

    1Division of Nephrology & Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 2Center for Epidemiology & Biostatistics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; 3Nephrology, Children's Hospital Colorado, Aurora, CO.

    Purpose: We aimed to study the renal outcomes of pediatric kidney transplant recipients following a previous non-renal solid organ transplantation (SOT).Methods: A retrospective analysis of…
  • 2016 American Transplant Congress

    Pre-Transplant Risk Factors: Predicting Nonadherence and Rejection in Adult Liver Transplant Recipients.

    S. Lieber,1 J. Helcer,1 E. Leven,1 C. Knight,2 C. Wlodarkiewicz,2 A. Shenoy,1 E. Shemesh,1 S. Florman,3 T. Schiano,3 R. Annunziato.1

    1Icahn School of Medicine Mount Sinai Hospital, NY; 2Fordham University, NY; 3Recanati/Miller Transplant Institute Mount Sinai Hospital, NY.

    Purpose: The pre-liver transplant (LT) psychosocial evaluation aims to identify risk factors for immunosuppression nonadherence (NA) and poor post-LT outcomes. Despite broad support for these…
  • 2016 American Transplant Congress

    Quality Improvement Initiative to Provide Comprehensive Pharmacy Services to Kidney Transplant Patients at a Small Transplant Center.

    J. Dickson,1 W. Vincent III,1 L. Wu,2 J. Thurman,1 J. Francis,3 M. Nuhn.4

    1Pharmacy, Boston Medical Center, Boston, MA; 2Northeastern University, Boston, MA; 3Renal Medicine, Boston Medical Center, Boston, MA; 4Transplant Surgery, Boston Medical Center, Boston, MA.

    Purpose: Previously, kidney transplant pharmacy services at our institution were limited to medication profile review before and after transplant surgery. Following an OPTN accreditation site…
  • 2016 American Transplant Congress

    How Small Is Too Small: A Comparison of Access and Survival by Weight in Pediatric Liver Transplant Recipients.

    E. Steen, R. Cotton, A. Rana.

    Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.

    Introduction: Orthotopic liver transplantation is a well-established treatment modality for a wide variety of pediatric illness. With its associated technical challenges, paucity of size-matched allografts,…
  • 2016 American Transplant Congress

    Pediatric Split Liver Transplantation: Single Center Experience.

    A. Elsabbagh,1,2 C. Williams,1 R. Girlanda,1 C. Desai,1 J. Hawksworth,1 A. Kroemer,1 C. Matsumoto,1 T. Fishbein.1

    1MedStar Georgetown Transplant Institute, Georgetown University Hospital, Washington, DC; 2Gastroenterology Surgical Center, Mansoura University, Mansoura, Egypt.

    Background: Split liver transplantation allows for expansion of the pool of organs for pediatric liver transplantation.Objectives: To assess overall outcomes in pediatric split liver transplantation…
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