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  • 2016 American Transplant Congress

    Do We Need an Individually Tailored Immunosuppression Strategy for Living Donor Kidney Transplant Recipients with PreTransplant Donor Specific Antibodies? A Retrospective Analysis.

    S. Bhutani,1 A. Ponnusamy,2 Q. Tak,1 S. Shah,1 J. Worthington,1 A. Summers,1 K. Poulton,1 D. Van Dellen,1 M. Morton,1 M. Picton.1

    1Department of Renal & Transplant Medicine, Manchester Royal Infirmary, Manchester, United Kingdom; 2Department of Renal Medicine, Royal Hospital Preston, Preston, United Kingdom.

    Introduction:Pre-Transplant Microbead donor HLA specific antibody(DSA) positive but cell crossmatch negative transplants are considered to be at increased immunological risk. This study aimed to address…
  • 2016 American Transplant Congress

    Management and Outcomes of Upper Extremity Deep Venous Thrombosis in Heart Transplant Patients.

    A. Panakos,1 D. Kramer,1 M. McCarey,1 P. Mather.2

    1Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA; 2Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA.

    Upper extremity deep venous thrombosis (UEDVT) is common in post-heart transplant (OHT) patients, likely due to their multiple intravascular catheters and post-surgical state. The clinical…
  • 2016 American Transplant Congress

    Four-Factor Prothrombin Complex Concentrate as a Strategy to Rapidly Reverse Anticoagulation in Patients Undergoing Cardiac Transplantation: Better Than the Conventional Approach?

    T. Sam,1 G. Gonzalez-Stawinski,2 G. Saracino,3 A. Jamil,3 S. Hall,2 K. Cox,1 B. Lima.2

    1Department of Pharmacy, Baylor University Medical Center, Dallas, TX; 2Heart Transplantation and Mechanical Circulatory Support, Baylor University Medical Center, Dallas, TX; 3Baylor Research Institute, Baylor University Medical Center, Dallas, TX.

    PurposeThe purpose of this analysis is to compare outcomes of administering four-factor prothrombin complex concentrate (4F-PCC, Kcentra™) versus standard of care for anticoagulation reversal in…
  • 2016 American Transplant Congress

    Basiliximab Induction for Safe Delay of Calcineurin Inhibitors in High MELD Liver Transplant Recipients.

    J. Clark,1 T. Sparkes,1 B. Masters,1 J. LaMattina,2 R. Barth,2 M. Moss.1

    1University of Maryland Medical Center, Baltimore, MD; 2University of Maryland School of Medicine, Baltimore, MD.

    Background: Available literature supports basiliximab induction for safe delay of CNI initiation and renal recovery; however there is a paucity of evidence for use in…
  • 2016 American Transplant Congress

    Quantitative Hepatitis C Virus (HCV) RNA in Plasma and Kidney Tissue in HCV Antibody Positive Donors.

    H. Shike,1 Z. Kadry,2 R. Shah,2 Y. Imamura,1 W. Greene,1 J. Gaspari,1 T. Riely,1 H. Nathan,3 R. Hasz,3 A. Jain.1

    1Surgery, Transplant, Hershey Medical Center, Hershey, PA; 2Pathology, Hershey Medical Center, Hershey, PA; 3OPO, Gift of Life Donor Program, Philadelphia, PA.

    Background: Currently HCV antibody positive deceased donors renal allografts are not considered for transplantation in HCV negative recipients. With recent development of anti-HCV therapy, utilization…
  • 2016 American Transplant Congress

    Replicative Senescence and Arteriosclerosis After Kidney Transplantation.

    K. De Vusser,1 D. Martens,2 E. Lerut,3 D. Kuypers,1 T. Nawrot,2 M. Naesens.1

    1Department of Nephrology and Renal Transplantation, UZ Leuven, Leuven, Belgium; 2Department of Imaging and Pathology, KULeuven, Leuven, Belgium; 3Centre for Environmental Sciences, U Hasselt, Hasselt, Belgium.

    BackgroundReplicative senescence is associated with telomere shortening. In native kidneys, obtained prior to transplantation, we recently described and validated a significant association between shorter intrarenal…
  • 2016 American Transplant Congress

    Same Policy, Different Impact: Center and Regional Effects of SHARE 35 Liver Allocation.

    D. Murken,1 A. Peng,1 D. Aufhauser Jr,1 D. Goldberg,2 M. Levine.1

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Medicine, University of Pennsylvania, Philadelphia, PA.

    Introduction: Early studies of national data suggest that Share-35 implementation was associated with more liver transplants, fewer discards, and lower waitlist mortality, without worsening of…
  • 2016 American Transplant Congress

    Factors Associated with Increased Risk of MELD Progression Among a Large Population of Patients with Cirrhosis and an Initial Low MELD Score (<15).

    K. Atiemo, L. Zhao, A. Skaro, L. VanWagner, S. Goel, A. Kho, B. Ho, R. Kang, S. Montag, J. Holl, M. Abecassis, D. Ladner.

    Northwestern University, Chicago.

    AimsLiving donor liver transplantation (LDLT) is an underutilized resource. Timely identification of patients with cirrhosis and a low MELD who's MELD score is likely to…
  • 2016 American Transplant Congress

    Risk Factors for Short and Long Term Mortality in High MELD Recipients.

    A. Bertacco,1,2 M. Rodriguez-Davalos,1 M. Schilsky,3 P. Yoo,1 S. Kulkarni,1 B. Fortune,3 A. Liapakis,3 S. Emre,1 D. Mulligan.1

    1Surgery, Yale University, New Haven; 2Dipartimento di Scienze Chirurgiche Oncologiche e Gastroenterologiche - DiSCOG, Padova University, Padova, Italy; 3Yale New Haven Transplant Center, Yale University, New Haven.

    The model for end-stage disease (MELD) score is used to stratify candidates for liver transplant (LT) based on objective measures. Since June 2013 with changes…
  • 2016 American Transplant Congress

    The Effect of Body Mass Index on Lung Transplant Outcomes.

    M. Kashem,1 A. Shiose,1 J. Abraham,1 N. Dean,1 S. Breves,1 F. Cordova,2 N. Patel,2 T. Yoshizumi,1 G. Criner,2 Y. Toyoda.1

    1Division of Cardiovascular Surgery, Temple University, Philadelphia, PA; 2Department of Thoracic Medicine and Surgery, Temple University, Philadelphia, PA.

    Background: Lung transplant (LTx) has the potential to effectively extend the life expectancy for patients with end-stage lung disease. Both high and low body mass…
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