2016 American Transplant Congress
CMV Immune Monitoring with a CMV ELISPOT Test in Kidney Transplant Patients.
Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Cytomegalovirus (CMV) is an important opportunistic infection in kidney transplant recipients (KTR). Whilst pre-emptive or prophylactic anti-viral regime reduce CMV complications, drug toxicity and resistance…2016 American Transplant Congress
Conditional Deletion of mTOR in Myeloid Cells Inhibits Chronic Allograft Rejection – A Novel Role for Macrophages in Transplant Vasculopathy.
Most transplants eventually lost to chronic rejection under potent immunosuppression therapies where activation of innate immunity is suspected to play a major role in graft…2016 American Transplant Congress
Impact of Early Hospital Readmission Following Simultaneous Pancreas Kidney Transplantation.
Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.
BACKGROUND: Our group recently demonstrated that 54% of simultaneous pancreas kidney (SPK) recipients experience early hospital readmission (EHR). It is unknown whether EHR following SPK…2016 American Transplant Congress
Metallothionein Accelerates Anti-MHC Induced Small Airway Obliteration and Fibrosis by Negatively Regulating IL-10 and Regulatory Cells.
Development of bronchiolitis obliterans syndrome (BOS), chronic lung allograft rejection, is a major obstacle to long-term success from lung transplantation. De novo antibodies (Abs) to…2016 American Transplant Congress
mTORC2 Negatively Regulates Dendritic Cell (DC) Metabolism and the Allostimulatory Function of Donor DCs in Organ Transplantation.
The mechanistic target of rapamycin (mTOR) is a kinase that functions in at least two complexes: rapamycin (RAPA)-sensitive mTORC1 and RAPA-insensitive mTORC2. These complexes play…2016 American Transplant Congress
Relationship Between Clinical Events and Everolimus Exposure at 12 Months in De Novo Renal Transplant Recipients.
We assessed the incidence of post-transplant biopsy-proven acute rejection (BPAR), graft loss and other adverse events (AEs) associated with everolimus (EVR) and tacrolimus (TAC) exposure…2016 American Transplant Congress
Acute Kidney Injury (AKI) Associated with Chronic Kidney Disease (CKD) in Paediatric Non-Kidney Transplant Recipients.
Background: Kidney dysfunction is common after solid organ transplantation; however, rates of post-transplant AKI and CKD in children are unknown.Objective: Determine rates of AKI and…2016 American Transplant Congress
Controlled Oxygenated Rewarming and Subnormothermic Machine Perfusion of Steatotic Livers: First Clinical Results.
IntroductionControlled oxygenated rewarming (COR) of cold stored livers by machine perfusion demonstrated convincing results in the first clinical pilot series (1). Here we report on…2016 American Transplant Congress
Proteoforms: Novel Biomarkers for Acute Rejection in Liver Transplant Recipients.
1Northwestern, Chicago; 2UPMC, Pittsburgh.
Background: Biomarker profiles diagnostic of acute rejection (AR) in liver transplant (LT) recipients could enhance the diagnosis and management of recipients. Our aim was to…2016 American Transplant Congress
Enhanced Activation of Hemostasis During Kidney Transplantation in Patients on Dialysis Compared to Pre-Emptively Transplanted Patients.
Groningen Transplant Center, University Medical Center Groningen, Groningen, Netherlands.
Introduction: It is generally assumed that dialysis patients (DP) have a more severe bleeding diathesis related to platelet dysfunction than pre-emptively transplanted patients (PEP) who…
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