2016 American Transplant Congress
Predictors of Ultrasound Failure to Detect Hepatocellular Carcinoma in Cirrhotic Livers.
University of California, San Francisco, San Francisco, CA.
Background: Current guidelines recommend ultrasound (US) for hepatocellular carcinoma (HCC) surveillance in cirrhotic livers. However, certain patient and disease characteristics may pose a technical challenge…2016 American Transplant Congress
Long-Term Assessment of the Safety and Efficacy of IVIG and Rituximab-Based Desensitization (DES).
Comprehensive Transplantation Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Introduction: HLA sensitized patients constitute a growing number of ESRD patients with an immunologic barrier to successful transplantation. Desensitization (DES) therapies have emerged to address…2016 American Transplant Congress
Muscle Function, Mass, and Quality in Obese Liver Transplant Candidates: Results from the Functional Assessment in Liver Transplantation (FrAILT) Study.
Background: Sarcopenia, or severe loss of muscle mass, is common in cirrhotics and adversely affects quality of life and transplant outcomes. Obese liver transplant(LT) candidates…2016 American Transplant Congress
Engineering a “Hybrid Thymus” to Promote Transplant Tolerance.
Purpose: Targeting the process of central (thymic) selection of developing T lymphocytes is the key tolerogenic mechanism of bone marrow transplantation (BM-Tx)-based protocols for transplant…2016 American Transplant Congress
CMV Immune Monitoring with a CMV ELISPOT Test in Kidney Transplant Patients.
Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.
Cytomegalovirus (CMV) is an important opportunistic infection in kidney transplant recipients (KTR). Whilst pre-emptive or prophylactic anti-viral regime reduce CMV complications, drug toxicity and resistance…2016 American Transplant Congress
Conditional Deletion of mTOR in Myeloid Cells Inhibits Chronic Allograft Rejection – A Novel Role for Macrophages in Transplant Vasculopathy.
Most transplants eventually lost to chronic rejection under potent immunosuppression therapies where activation of innate immunity is suspected to play a major role in graft…2016 American Transplant Congress
Impact of Early Hospital Readmission Following Simultaneous Pancreas Kidney Transplantation.
Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.
BACKGROUND: Our group recently demonstrated that 54% of simultaneous pancreas kidney (SPK) recipients experience early hospital readmission (EHR). It is unknown whether EHR following SPK…2016 American Transplant Congress
Metallothionein Accelerates Anti-MHC Induced Small Airway Obliteration and Fibrosis by Negatively Regulating IL-10 and Regulatory Cells.
Development of bronchiolitis obliterans syndrome (BOS), chronic lung allograft rejection, is a major obstacle to long-term success from lung transplantation. De novo antibodies (Abs) to…2016 American Transplant Congress
mTORC2 Negatively Regulates Dendritic Cell (DC) Metabolism and the Allostimulatory Function of Donor DCs in Organ Transplantation.
The mechanistic target of rapamycin (mTOR) is a kinase that functions in at least two complexes: rapamycin (RAPA)-sensitive mTORC1 and RAPA-insensitive mTORC2. These complexes play…2016 American Transplant Congress
Relationship Between Clinical Events and Everolimus Exposure at 12 Months in De Novo Renal Transplant Recipients.
We assessed the incidence of post-transplant biopsy-proven acute rejection (BPAR), graft loss and other adverse events (AEs) associated with everolimus (EVR) and tacrolimus (TAC) exposure…
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