ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    The Finances of Broader Sharing of Livers Following Share 35.

    A. Harper,1 E. Edwards,1 R. Gilroy,2 W. Chapman,3 D. Mulligan,4 G. Klintmalm.5

    1Research, UNOS, Richmond, VA; 2Univ.of Kansas Med Ctr, Kansas City, KS; 3Washington Univ, St Louis, MO; 4Yale Med Ctr, New Haven, CT; 5Baylor Univ, Houston, TX.

    Background. After implementation of the “Share 35” policy in 2013, many centers and OPOs reported increased costs associated with broader sharing. The OPTN Liver and…
  • 2016 American Transplant Congress

    Influence of the Tacrolimus Metabolism Rate on BKV Infection After Kidney Transplantation.

    G. Thölking,1 C. Schmidt,1 K. Schuette-Nuetgen,1 D. Pabst,1 R. Koch,2 H. Wolters,3 S. Reuter,1 B. Suwelack.1

    1Department of Medicine D, Division of General Internal Medicine, Nephrology and Rheumatology, University Hospital of Münster, Münster, Germany; 2Institute of Biometrics and Clinical Research, University of Münster, Münster, Germany; 3Department of General Surgery, University Hospital of Münster, Münster, Germany.

    Introduction: BK virus (BKV) infection is a serious complication following renal transplantation (RTx). The minimization of risk factors that predict BKV infection might help to…
  • 2016 American Transplant Congress

    Implementation of Telehealth Is Associated with Improved Timeliness of Kidney Transplant Waitlist Evaluation at a VA Center.

    R. Forbes,1,2 K. Kummerow Broman,1,2 T. Johnson,2 D. Rybacki,2 M. Hagemann,2 A. Hannah-Gillis,2 I. Feurer,1 D. Hale.1,2

    1TN Valley HS, Nashville, TN; 2Vanderbilt University Medical Center, Nashville, TN.

    Background: The VA National Transplant Program is challenged to provide timely kidney transplant evaluation for Veterans nationwide. Efforts to improve access have included implementing a…
  • 2016 American Transplant Congress

    Predictive Model for Medication Errors in a Chronic Kidney Transplant Clinic.

    K. Covert,1 C. Mardis,1 J. Fleming,1 A. Mardis,1 H. Meadows,1 N. Pilch,1 P. Mohan,2 M. Posadas,2 M. Salazar,2 T. Srinivas,2 G. Mour,2 D. Taber.1

    1Pharmacy, The Medical University of South Carolina, Charleston, SC; 2Transplant Nephrology, The Medical University of South Carolina, Charleston, SC.

    Medication errors are associated with increased incidence of infection, rejection, and graft loss in kidney transplant recipients. This study aims to create a model to…
  • 2016 American Transplant Congress

    Surgical Site Infection Does Not Fully Explain the Impact of Obesity on Post-Transplant Outcomes.

    S. Bae, L. Kucirka, A. Massie, D. Segev.

    Johns Hopkins, Baltimore, MD.

    While obesity is considered a risk factor for worse survival after kidney transplant (KT), a single-center study reported that obesity has no direct effect on…
  • 2016 American Transplant Congress

    Is Pretransplant Determination of Hepatocellular Carcinoma Tumor Grade Using Needle Biopsy Reliable for Transplant Candidate Selection? Analysis of 217 Liver Transplant Recipients.

    C. Court, M. Harlander-Locke, D. Markovic, F. Kaldas, A. Zarrinpar, D. Farmer, S. Sho, J. Tomlinson, J. Hiatt, R. Busuttil, V. Agopian, D. Lu, S. Raman.

    Department of Surgery, UCLA, Los Angeles, CA.

    Objective: Despite the prognostic significance of tumor grade and vascular invasion for patients with hepatocellular carcinoma (HCC), preoperative needle biopsy (PNB) is not routinely utilized…
  • 2016 American Transplant Congress

    RNAseq Transcriptome Analysis of Bone Marrow CD138+ Plasma Cell Responses to Carfilzomib Monotherapy Desensitization.

    J. Driscoll, B. Aronow, S. Tremblay, R. Alloway, E. Woodle.

    Medicine, Surgery, Biomedical Informatics, U of Cincinnati, Cincinnati Children's, Cincinnati, OH.

    Purpose: Prior studies indicate that bone marrow resident plasma cells (BMRPCs) demonstrate varying sensitivity to proteasome inhibition (PI). Effects of carfilzomib (CFZ) monotherapy desensitization on…
  • 2016 American Transplant Congress

    Activated Cytoprotective Mechanisms in DBD Kidneys Correlate with Kidney Function in Transplant Recipients: A Study Using Clinical Samples from the UK QUOD Biobank.

    M. Kaisar,1 L. van Dullemen,2 Z. Akhtar,1 M. Lo Faro,1 H. Huang,1 H. Leuvenink,2 B. Kessler,1 R. Ploeg.1

    1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; 2UMCG, UMCG, Groningen, Netherlands.

    The onset of abnormal pathophysiological changes following brain death adversely impact kidney function following transplantation. Understanding the biological mechanisms that affect kidney quality will allow…
  • 2016 American Transplant Congress

    Early Conversion to Everolimus in De Novo Renal Transplant Recipients: Incidence of Viral Infections in the Randomized-Controlled ELEVATE Study.

    H. Hirsch,1 J. De Fijter,1 M. van der Giet,1 M. Zeier,1 J. Pascual,1 Y. Avihingsanon,1 P. Lopez,2 J. Aguilar-Sanchez,2 J. Kochuparampil,2 Z. Wang,3 H. Holdaas,1 J. Cruzado.1

    1ELEVATE Study Group, Basel, Switzerland; 2Novartis, Basel, Switzerland; 3Novartis Pharmaceutical Corporation, East Hanover.

    BackgroundCytomegalovirus (CMV) and BK polyomavirus (BKPyV) infections are independent risk factors for acute rejection and graft loss. Early conversion from calcineurin inhibitors (CNIs) to everolimus…
  • 2016 American Transplant Congress

    Assessing Return of CMV Specific Cellular Immunity Using the T-SPOT.CMV Soon After Kidney Transplant with Thymoglobulin.

    C. Kotton.

    Infectious Disease, Massachusetts General Hospital, Boston, MA.

    Background: We do not currently have sufficient predictive tools to determine risk of CMV infection after organ transplantation. Recent data suggest that assays of the…
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