Am J Transplant, Volume 16, Suppl 3 Archives - Page 165 of 180 - ATC Abstracts

2016 American Transplant Congress
FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.
S. Afelik,¹ N. Yonan,¹ B. Pool,² J. Jensen,² J. Oberholzer.¹
¹Surgery, Division of Transplantation, University of Illinois, Chicago, IL; ²Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Foundation, Cleveland, OH.
Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…
2016 American Transplant Congress
Delaying the Induction of Mixed Chimerism Until Two Months After NHP Heart and Kidney Cotransplantation Results in Long Term Survival.
K. Huh,¹ M. Tonsho,¹ P. Spencer,¹ J. Paster,¹ X. Wu,¹ I. Hanekamp,¹ T. Kawai,^1,3 R. Smith,² A. Cosimi,¹ A. Dehnadi,¹ G. Benichou,¹ R. Colvin,^1,2 J. Madsen.^1,4
¹Center for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Boston, MA; ²Department of Pathology, Massachusetts General Hospital, Boston, MA; ³Department of Surgery, Massachusetts General Hospital, Boston, MA; ⁴Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, MA.
Background. We have previously achieved delayed tolerance in cynomologous recipients cotransplanted with heart and kidney allografts by treating recipients with standard triple drug immunosuppression for…
2016 American Transplant Congress
MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-β1 Induced Human Bronchial Epithelial Cells.
S. Ladak, C. Ward, S. Ali.
Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
The role of TGF-β1 in mediating extracellular matrix remodeling during the pathogenesis of lung fibrosis has been well defined. Dysregulated expression of miRNA is increasingly…
2016 American Transplant Congress
Trends in Aspergillus Infection After Liver Transplantation, 1988-2014.
R. Al Masri, L. Jennings, S. Asrani, G. Klintmalm, C. Spak.
Transplant Hepatology/Transplant Surgery/Infectious Disease, Baylor University Medical Center, Dallas, TX.
Background: Invasive Aspergillosis is an important cause of morbidity and mortality in liver transplant recipients. Aspergillus may account for up to 25% of all fungal…
2016 American Transplant Congress
Early Enteral Feeding After Living Donor Liver Transplantation Prevents Infectious Complications: A Prospective Pilot Study.
J. Kim,¹ D. Sinn,² S. Lee,¹ G.-S. Choi,¹ J. Park,¹ C. Kwon,¹ S. Kim,¹ J.-W. Joh,¹ S.-K. Lee.¹
¹Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; ²Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Background: Infectious complications, including bacteria, virus, and fungus, often occur after liver transplantation and are the most frequent cause of in-hospital mortality. The present study…
2016 American Transplant Congress
Kidney Transplants from Anuric Deceased Donors on Renal Replacement Therapy.
W. Bry, J. Bellingham, S. Katznelson, P. Patel, K. Ueda, H. Mahanty, N. Neidlinger, A. Hassoun, V. Peddi.
Transplantation, California Pacific Medical Center, San Francisco, CA.
Transplantation of deceased donor kidneys with Acute Kidney Injury (AKI) has become a generally well accepted practice with excellent results documented in the literature. The…
2016 American Transplant Congress
Conversion to Belatacept as Rescue Therapy in Kidney Transplant Recipients with Severe Graft Dysfunction.
F. Oldhafer,¹ M. Hiss,² A. Schwarz,² H. Haller,² G. Einecke.²
¹Clinic for General, Abdominal and Transplant Surgery, Hannover Medical School, Hannover, Germany; ²Clinic for Nephrology, Hannover Medical School, Hannover, Germany.
Belatacept is a fusion protein that prevents T cell co-stimulation via the CD28 receptor. If used as first-line therapy, immunosuppression with Belatacept is associated with…
2016 American Transplant Congress
Pediatric Kidney Transplantation and Mortality: Distance to Transplant Center Matters.
J. Adler, Y. Bababekov, J. Markmann, D. Chang, H. Yeh.
Surgery, Massachusetts General Hospital, Boston, MA.
INTRODUCTION: The distance traveled by adults to kidney transplant centers contributes to disparities in access and outcomes. We hypothesized that distance would adversely affect the…
2016 American Transplant Congress
Sublingual Tacrolimus in Liver Transplantation: A Valid Option?
M. Moreno Gonzales,¹ L. Myhre,² T. Taner.¹
¹Division of Transplantation Surgery, Mayo Clinic, Rochester, MN; ²Department of Pharmacy, Mayo Clinic, Rochester, MN.
Introduction. Oral tacrolimus (Tac) is currently the pilar of maintenance immunosuppression following solid organ transplantation and the most common route of drug delivery. Recent studies…
2016 American Transplant Congress
Economic Analysis of Survival for Patients Undergoing Kidney Transplant in a Philanthropic Hospital of Sao Paulo, Brazil.
A. Matos,¹ D. Malheiros,² S. Morgado,¹ L. Requiao-Moura,¹ A. Kanamura,³ M. Cendoroglo,³ O. Pavao Santos,³ A. Pacheco-Silva.¹
¹Renal Transplantation Unit, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; ²Health Economy Department, Hospital Israelita Albert Einstein, Sao Paulo, Brazil; ³Management Department, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.
Brazil has one of the most important public programs of transplant in the world. Our hospital is a private philanthropic that has already performed more…