Am J Transplant, Volume 16, Suppl 3 Archives - Page 157 of 180 - ATC Abstracts

2016 American Transplant Congress
B Cell Signature Profiling in Kidney Transplant Patients on Thymoglobulin.
A. Benitez,¹ T. Milford,² K. Torralba,³ K. Payne,² M. De Vera.¹
¹Transplantation Institute, Loma Linda University Health Care, Loma Linda, CA; ²Basic Science Division of Anatomy, Loma Linda University, Loma Linda, CA.
Purpose: B cell subsets could be used as biomarkers to modulate therapy regimens in kidney transplant patients. B cell subsets occur with varying proportions within…
2016 American Transplant Congress
Induction Therapy with Depleting Antibodies in Low Immunological Risk Renal Transplant Patients Treated with a Steroid Free Regimen – Comparison of Alemtuzumab vs. Antithymocyte Globulin.
N. Bossini,¹ S. Sandrini,¹ R. Tardanico,² F. Valerio,¹ G. Setti,¹ C. Salviani,¹ S. Possenti,¹ P. Foini,¹ E. Marta,¹ G. Cancarini.¹
¹Division and Chair of Nephrology, A.O "Spedali Civili" and University, Brescia, Italy; ²Division and Chair of II Laboratory of Pathology, A.O "Spedali Civili" and University, Brescia, Italy.
Induction therapy with depleting antibodies reduces rejection rate and potentially improves efficacy of steroid free regimens after renal transplantation.This prospective, single-centre, cohort study evaluated cumulative…
2016 American Transplant Congress
Resolution of Undefined Etiology of Respiratory Infections in Lung Transplant Patients with Unbiased Metagenomic Sequencing.
N. Mueller,¹ D. Lewandowska,² B. Ruehe,² P. Schreiber,¹ O. Zagordi,² F. Geissberger,² M. Schuurmans,³ M. Greiner,¹ A. Zbinden,² J. Boeni,² C. Benden,³ A. Trkola,² M. Huber.²
¹University Hospital Zurich, Division of Infectious Diseases, Zurich, Switzerland; ²University of Zurich, Institute of Medical Virology, Zurich, Switzerland; ³University Hospital Zurich, Division of Pulmonary Medicine, Zurich, Switzerland.
Study Purpose A high number of post-transplant infections with respiratory symptoms remain unresolved, despite routine testing for the common respiratory viruses. Using an open metagenomic…
2016 American Transplant Congress
Early Alloantibody Responses Against Donor MHC Class I and Class II Molecules Are Differentially Affected by Prolonged Cold Ischemia Storage of Renal Allografts.
V. Gorbacheva, R. Fan, W. Baldwin, A. Valujskikh.
Immunology, Cleveland Clinic Foundation, Cleveland, OH.
Prolonged cold ischemia storage (CIS) of donor transplants is a major risk factor for acute and chronic graft tissue injury. Despite strong clinical correlations between…
2016 American Transplant Congress
Impact on Renal Function of Stepwise Withdrawal of Tacrolimus Combined with Everolimus and EC-MPS vs Standard Treatment Combining Tacrolimus and EC-MPS in De Novo Liver Transplant Recipients: Results of the SIMCER Study.
F. Saliba,¹ C. Duvoux,² S. Dharancy,³ J. Dumortier,⁴ Y. Calmus,⁵ F. Di Giambattista,⁶ F. Conti.⁵
¹Hôpital Paul Brousse, Villejuif, France; ²Hôpital Henri Mondor, Créteil, France; ³Hôpital Claude Huriez, Lille, France; ⁴Hôpital Edouard Herriot, Lyon, France; ⁵Hôpital La Pitié-Salpêtrière, Paris, France; ⁶Novartis Pharma SAS, Rueil-Malmaison, France.
Introduction: Long-term post-liver transplant (LTx) complications, particularly impaired renal function (RF) and its consequences, remain a concern. Presented here are the results of the SIMCER…
2016 American Transplant Congress
Positive Lymphocytes Flow Cytometry Crossmatch Due to AT1r Antibodies in Absence of HLA-DSA.
M. Ramirez,¹ D. Kershaw,² Y. Huang,² J. Magee,³ M. Samaniego,² T. Williams,¹ D. Schauss,¹ T. Franks,¹ Y. Kleyman,¹ D. Ramon.¹
¹Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI; ²Department of Internal Medicine, UMICH, Ann Arbor; ³Department of Surgery, UMICH, Ann Arbor.
The angiotensin II type 1 receptor (AT1r) plays a key role in the renin-angiotensin system. Anti-AT1R antibodies (Abs) have been associated with both acute and…
2016 American Transplant Congress
Natural History of Response to Wounding in Human Kidney Transplants.
K. Famulski,¹ J. Venner,^2,1 J. Reeve,¹ P. Halloran.¹
¹University of Alberta, Edmonton, AB, Canada; ²University of Queensland, Brisbane, Queensland, Australia.
In both primary kidney diseases and kidney transplants, the extent of fibrosis is a key indicator of stage, progression, and prognosis. Much debate focuses, however,…
2016 American Transplant Congress
Impact of Cold Ischemia Time on the Outcomes of Kidneys with KDPI >85%: Mate Kidney Analysis.
M. Sampaio, B. Chopra, K. Sureshkumar.
Nephrology, Allegheny General Hospital, Pittsburgh, PA.
The new kidney allocation scheme recommends simultaneous local and regional offer for kidneys with KDPI >85% in order to minimize discard rates. It is unclear…
2016 American Transplant Congress
Hepatitis E Virus (HEV) Infection Among Kidney Transplant Patients in a Northeast US Center.
M. Lim,¹ S. Kamili,² T. Greene,² A. Tejada-Strop,² J. Drobeniuc,² M. Vanderveen,¹ R. Bloom.¹
¹Division of Nephrology, Perelman School of Medicine, Philadelphia, PA; ²Division of Viral Hepatitis, Centers for Disease Control, Atlanta, GA.
Aim. To determine the prevalence of HEV infection in kidney candidates and assess chronic HEV infection among transplant recipients. Methods. We recruited 244 kidney transplant…
2016 American Transplant Congress
Recurrence of FSGS Post Kidney Transplantation: Salvage Therapy with ACTHAR® Gel.
P. Vaitla, D. Daswatta, A. Guasch.
Transplant, Emory University, Atlanta, GA.
Recurrence of FSGS post kidney transplantation: Salvage therapy with ACTHAR® gel.Introduction:Recurrence of FSGS post kidney transplantation may reach 25-50%. Failure of treatment or incomplete remission…