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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Improving the Efficiency, Safety and Cost of Evaluating Living Donor Liver Candidates Using Single Sequence MRI.

    M. Schilsky,1,2 K. Cartiera,1 S. Boga,1 S. Schilsky,3 S. Emre,1 D. Mulligan,1 J. Weinreb,1 G. Israel.1

    1Yale New Haven Transplantation Center, Transplantation and Immunology, Surgery, Yale University, New Haven, CT; 2Section of Digestive Diseases, Medicine, Yale University, New Haven, CT; 3Food and Drug Administration, Silver Springs, MD.

    Background: Current evaluation of donor candidates for adult-to-adult living donor liver transplant (LDLT) includes MRI and CT without and with contrast for defining liver anatomy.…
  • 2016 American Transplant Congress

    Antibody-Mediated Rejection in Pancreas Transplantation.

    O. Serrano,1 D. Vock,2 E. Finger,1 R. Kandaswamy,1 D. Sutherland,1 T. Dunn.1

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics, University of Minnesota, Minneapolis, MN.

    PURPOSE: The diagnostic criteria for antibody-mediated rejection (AMR) in pancreas transplantation (PTx) is evolving. The incidence and long-term effect of AMR have not been well-described.…
  • 2016 American Transplant Congress

    Surveillance Renal Allograft Biopsies Prognosticate Graft Function.

    J. Thompson, D. Taber, P. Baliga, K. Chavin, T. Srinivas.

    MUSC, Charleston, SC.

    Background: Surveillance biopsy of the renal allograft provides a window into the health of the allograft and could allow prognostication of function by affording better…
  • 2016 American Transplant Congress

    Early Hospital Readmission Following Kidney Re-Transplantation.

    E. King, B. Orandi, S. Bae, X. Luo, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: Among first time kideny transplant (KT) recipients the incidence of early hospital readmission (EHR) is 31%. Kidney re-transplants are more complex and we hypothesize…
  • 2016 American Transplant Congress

    Predicting Obstructive Coronary Artery Disease in Asymptomatic Patients Undergoing Renal Transplantation Using a Simple Risk Score.

    D. Moutzouris, C. Baker, M. Willicombe, N. Duncan, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    PurposeCoronary angiography in asymptomatic patients with End Stage Renal Disease (ESRD) shows significant Coronary Artery Disease (CAD) (stenosis >50%) in 37-53% of patients. We have…
  • 2016 American Transplant Congress

    Tolerance Induction with Donor Bone Marrow Transplantation in Kidney Transplantation.

    H. Park,1 N. Lee,1 S. Lee,1 G. Choi,1 C. Kwon,1 S. Kim,1 J.-W. Joh,1 M. Kim,2 Y. Kwon,2 S.-K. Lee.1

    1Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Transplantation Research Center, Samsung Biomedical Research Institute, Seoul, Republic of Korea.

    Tolerance induction is considered to be a final goal in the field of organ transplantation. We have performed simultaneous bone marrow and kidney transplantation in…
  • 2016 American Transplant Congress

    Factors Associated with Mortality Among a Large Population of Patients with Cirrhosis and a Low MELD (<15).

    K. Atiemo, L. Zhao, A. Skaro, L. VanWagner, S. Goel, A. Kho, B. Ho, R. Kang, S. Montag, J. Holl, M. Abecassis, D. Ladner.

    Northwestern University, Chicago.

    AimStudies suggest that certain patients with liver cirrhosis and a low MELD score (<15) remain at high risk for mortality. Current data is largely limited…
  • 2016 American Transplant Congress

    Erythropoietin (EPO) Mediates Spontaneous Kidney Transplant Tolerance in Mice.

    P. Cravedi,1 C. Purroy,1 J. Madsen,2 R. Fairchild,3 T. Tanaka,3 W. Baldwin 3rd,3 A. Alessandrini,2 P. Heeger.1

    11Icahn School of Medicine at Mount Sinai, New York, NY; 2Transplantation Biology Research Center, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA; 33Department of Immunology, Cleveland Clinic Foundation, Cleveland.

    Spontaneous allogeneic kidney transplant tolerance occurs in mice, but the underlying mechanisms are unknown. Building upon recent human data showing that EPO, an erythropoietic hormone…
  • 2016 American Transplant Congress

    Combined CD122 and Costimulation Blockade Prolongs Allograft Survival by Controlling Expansion and Effector Function of Memory CD8 T Cells.

    D. Mathews,1 Y. Dong,1 L. Higginbotham,1 S. Kim,1 C. Breeden,1 J. Tso,2 A. Adams.1

    1Emory Transplant Center, Emory University, Atlanta, GA; 2JN Biosciences, Mountain View, CA.

    CD8 memory T cells rely on signaling through CD122, the shared IL-2 and IL-15 receptor β-chain. The addition of anti-CD122 to costimulation blockade prolongs graft…
  • 2016 American Transplant Congress

    Dilution of Patient Sera Improves MFI Correlation with Complement Fixation in Solid Phase Assay Assessment.

    C. Castleberry,1 D. Phelan,2 K. Simpson,1 T. Mohanakumar,3 C. Canter.1

    1Pediatric Cardiology, Washington University School of Medicine, St. Louis, MO; 2Histocompatibility Laboratory, Barnes-Jewish Hospital, St. Louis, MO; 3Surgery, Washington University School of Medicine, St. Louis, MO.

    Background: Median Fluorescent Intensity (MFI) by solid phase assays (SPA) has been used to determine risk of donor-recipient reaction prior to transplant. Inconsistency of this…
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