ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Give One and Done? Evaluating a Change in Surgical Prophylaxis in Kidney Transplant Recipients.

    K. Bliven, C. Truax, K. Snow, N. Kenyon, A. Carlson, S. Yeager, L. Smith.

    Pharmacy, University of Utah Hospital and Clinics, Salt Lake City, UT.

    Surgical-site infections (SSIs) occur in up to 11% of kidney transplant (txp) patients (pts). There is no consensus on the optimal peri-op prophylaxis regimen for…
  • 2016 American Transplant Congress

    Mycophenolate Mofetil Dose Reduction Are Associated with the Risk of Acute Rejection and Graft Failure After Renal Transplantation.

    A. El-Agroudy,1 A. Taher,2 A. Alaradi,2 B. Alhayki,2 S. Gareeb,2 E. Farid.2

    1Internal Medicine, College of Medicine, Arabian Gulf University, Manama, Bahrain; 2Nephrology, Salmaniya Medical Complex, Manama, Bahrain.

    Background: Mycophenolate mofetil (MMF) is a highly effective immunosuppressive agent in transplant therapy. Although MMF is generally well tolerated, optimal therapy may be limited by…
  • 2016 American Transplant Congress

    Outcomes of Ribavirin Free Treatment of Recurrent Genotype 1 , Hepatitis C Infection Post Liver Transplant.

    D. Jones,1 S. Baggett,1 M. Shoreibah,2 O. Massoud.2

    1Department of Pharmacy, UAB Hospital, Birmingham, AL; 2Department of Gastroenterology, UAB Hospital, Birmingham, AL.

    Background. With the development of direct-acting antivirals, the treatment of Hepatitis C Virus (HCV) has become a rapidly changing area of medical practice. Data on…
  • 2016 American Transplant Congress

    Potential Biomarkers and Treatment for BK Virus Associated Nephropathy.

    M. Borkar,1 V. Srivastava,2 R. Cunnington,1 T. Sharma,1 L. Tibbles.1

    1Faculty of Mediicne, University of Calgary, Calgary, AB, Canada; 2CSIR-Indian Institute of Toxicology Research, Lucknow, Uttar Pradesh, India.

    Background: BK polyomavirus assoiciated nephropathy (BKVAN) is one of the major complications in renal transplants, and is associated with significant fibrosis It is important to…
  • 2016 American Transplant Congress

    Donor-Specific Antibody Is a Major Independent Predictor of Accelerated Heart Allograft Vasculopathy (CAV).

    M. Bories,1 S. Varnous,2 C. Lefaucheur,3 P. Rouvier,2 R. Guillemain,1 P. Bruneval,1 J. Duong Van Huyen,4 A. Loupy.4

    1European Georges Pompidou Hospital, Paris, France; 2La Pitié Salpêtrière Hospital, Paris, France; 3Saint-Louis Hospital, Paris, France; 4Necker Hospital, Paris, France.

    Introduction The role of circulating DSA in addition to traditional cardiovascular risk factors, in the development of accelerated CAV have not been demonstrated. We investigated…
  • 2016 American Transplant Congress

    Intestinal Retransplantation in Children: Single Center Experience.

    N. Celik,1 F. Vyas,1 G. Bond,1 K. Soltys,1 J. Rudolph,2 R. Sindhi,1 G. Mazariegos.1

    1Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; 2Intestinal Care and Rehabilitation Center, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

    Aim: To analyze the patient and graft characteristics and improvement in patient outcomes for intestinal retransplantation (Re-ITx) in the era of induction immunosuppression with the…
  • 2016 American Transplant Congress

    Targeting the Constitutively Active PI3K/Akt/mTOR Signaling Pathway in Epstein-Barr Virus B Cell Lymphomas.

    A. Sang, G. Ivison, C. Esquivel, S. Krams, O. Martinez.

    Division of Abdominal Transplantation, Stanford School of Medicine, Stanford, CA.

    Epstein-Barr virus (EBV) B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD) is a major problem in organ transplantation. Reduction of immunosuppression sometimes result in tumor…
  • 2016 American Transplant Congress

    Assessing the Impact of the Share35 Liver Allocation Policy: Survival Outcomes Among Liver Re-Transplant Recipients.

    J. Ortiz,1 N. Koizumi,2 C. Kwon,2 Y. Zhang,2 C. Ortiz.3

    1Department of Surgery, University of Toledo, Toledo, OH; 2George Mason University, Fairfax, VA; 3Bucknell University, Lewisburg, PA.

    Liver retransplantation (reLTx) is the only treatment option for those who experienced graft loss after primary liver transplantation (LTx). Yet, in an era of increasing…
  • 2016 American Transplant Congress

    Immune Response to BK Virus in Renal Transplant Recipients.

    D. DeWolfe,1 J. Gandhi,1 M. Mackenzie,1 T. Broge,1 E. Bord,1 D. Mandelbrot,1 R. Viscidi,2 F. Cardarelli,1 M. Pavlakis,1 C. Tan.1

    1Medicine, Beth Israel Deaconess Medical Center, Boston, MA; 2Pediatrics, Johns Hopkins Medical Center, Baltimore, MD.

    Background: The adaptive immune characteristics associated with BK Virus (BKV) infection and control remain incompletely described. In this study we further elucidate the immune response…
  • 2016 American Transplant Congress

    AT1R Antibodies at 1-Year Negatively Impact 5-Year Native Renal Function in Liver Transplant Recipients.

    J. O'Leary,1 A. Philippe,2 H. Heidecke,2 R. Freeman,1 L. Jennings,1 R. Catar,2 G. Klintmalm,1 D. Dragun.2

    1Baylor Simmons Transplant Insttute, Baylor University Medical Center, Dallas, TX; 2Internal Medicine, Charite, Berlin, Germany.

    Angiotensin II Type-1 Receptor (AT1R) antibodies have been associated with pulmonary hypertension, renal allograft loss, and fibrosis progression in liver allograft recipients especially if combined…
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