Am J Transplant, Volume 16, Suppl 3 Archives - Page 148 of 180 - ATC Abstracts

2016 American Transplant Congress
Recall Alloantibody Production Is Driven by CD138⁺ Cells Proliferating in the Spleens: An Indication for Long-Lived Plasma Cell Activities and Potential Therapeutic Target.
I. Kim, N.-N. Chai, A. Klein, S. Jordan, G. Wu.
Comprehensive Transplantation Center/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Background Donor-specific antibodies (DSA) generated in recall responses are produced by long-lived plasma cells (L-PC) residing in the bone marrows (BM). Mechanisms of L-PC activation,…
2016 American Transplant Congress
The Property of Modulatory T Cells Generated by Mixed Lymphocyte Culture with CD154 Blockade.
K. Hotta, T. Oura, B. Cosimi, T. Kawai.
Center for Transplantation Science, Massachusetts General Hospital, Boston, MA.
Background:Regulatory T cell (Treg) immunotherapy has been applied to minimize the immunosuppressive drugs in clinical transplantation. To avoid contamination of CD4+CD25- T cells, only highly…
2016 American Transplant Congress
Eliminating Xenoantigen Expression on Swine Red Blood Cells.
Z.-Y. Wang,¹ G. Martens,¹ R. Blankenship,¹ R. Sidner,¹ P. Li,¹ J. Estrada,¹ M. Tector,² A. Tector.^1,3
¹Surgery, Indiana University School of Medicine, Indianapolis, IN; ²Surgery, Indiana University Health, Indianapolis, IN; ³Indiana University Health Transplant Institute, Indianapolis, IN.
Background:The rapidly improving tools of genetic engineering may make it possible to overcome humoral immune barrier that prevents xenotransplantation. We hypothesize that levels of human…
2016 American Transplant Congress
Effect on Endothelial function when Hyperglycemia Is Reversed by Single Pancreas Transplantation.
T. Halden,^1,2 I. Eide,^1,2 D. Dahle,¹ A. Åsberg,^1,3 A. Reisæter,¹ T. Jenssen,^1,4 A. Hartmann.^1,2
¹Department of Transplant Medicine, Section of Nephrology, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ²Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; ³Department of Pharmaceutical Biosciences, School of Pharmacy, University of Oslo, Oslo, Norway; ⁴Metabolic and Renal Research Group, UiT, The Arctic University of Norway, Tromsø, Norway.
Background: Endothelial dysfunction is a predictor for future cardiovascular disease. We have previously published that endothelial function improves in renal transplant recipients with post-transplantation diabetes…
2016 American Transplant Congress
What Is the Decline Rate of Pancreata Attributed to Donation After Cardiac Death When the Accompanied Kidney Is Transplanted?
T. Alhamad,¹ K. Lentine,² A. Taha,² J. Wellen,¹ D. Brennan.¹
¹Washington University in St. Louis, St. Louis; ²Saint Louis University, St. Louis.
Background:Pancreas transplantation in the U.S. has declined steadily in the U.S. over the past decade despite international growth of the practice. Reasons for this decline…
2016 American Transplant Congress
Assessing the Induction of Tolerance to Vascularized Composite Allotransplantation in Miniature Swine.
J. Walch, J. Alonso-Escalante, H. Wang, B. Oh, M. Iglesias, A. Lee, G. Brandacher, G. Raimondi.
Plastic and Reconstructive Surgery, Johns Hopkins Medical Institute, Baltimore, MD.
Purpose: Miniature swine is a pre-clinical large animal model well suited to validate protocols of tolerance induction to vascularized composite allotransplantation (VCA). However, tools to…
2016 American Transplant Congress
ABO-Incompatible Living Kidney Transplantation at Multicenter Japanese Case Series: Evolution of Outcomes and Immunosuppressive Management.
K. Tanabe,¹ M. Okumi,¹ M. Furusawa,¹ K. Unagami,¹ T. Hirai,¹ H. Shirakawa,² T. Shimizu,¹ K. Omoto,³ M. Inui,¹ H. Ishida.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Urology, Ohkubo Hospital, Tokyo, Japan; ³Urology, Todachuo General Hospital, Saitama, Japan.
[lsaquo]Background[rsaquo]ABO-incompatible living kidney transplantation (ABO-ILKT) has been performed to broaden the range of donor types used for living related kidney transplantation (LKT). Recently, ABO-ILKT has…
2016 American Transplant Congress
Outcomes of Donor Nephrectomy in the Elderly.
O. Serrano,¹ A. Bangdiwala,² K. Yadav,¹ A. Adamusiak,¹ D. Vock,³ W. Payne,¹ T. Dunn,¹ S. Chinnakotla,¹ E. Finger,¹ T. Pruett,¹ A. Matas,¹ R. Kandaswamy.¹
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics and Bioinformatics Core, Masonic Cancer Center, Minneapolis, MN; ³Biostatistics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: The critical organ shortage has increased demand for marginal donor kidneys. Although previously a contraindication to live kidney donation, advanced age donors (>60 y.o.)…
2016 American Transplant Congress
Establishing a Learning Curve for Laparoscopic Living Donor Nephrectomy.
Z. Ahmed, R. Tamburrini, R. Uwechue, P. Chandak, F. Calder, N. Kessaris, N. Mamode.
Abdominal Transplant Unit, Guy's Hospital, London, United Kingdom.
Despite thousands of hand assisted laparoscopic donor nephrectomies (HALDNs) having been performed a paucity of data still exists in establishing how many procedures are required…
2016 American Transplant Congress
Continuous Antithymocyte Globulin (rATG) for Treatment of Renal Allograft Rejection: Preliminary Analysis of a Prospective, Randomized Trial.
S. Patel, R. Knight, S. Kuten, J. Nolte, A. Gaber.
Houston Methodist Hospital, Houston, TX.
Intravenous (IV) rATG for acute rejection (AR) is primarily given on an inpatient basis due to its daily administration, IV access requirement, and monitoring. The…