Am J Transplant, Volume 16, Suppl 3 Archives - Page 142 of 180 - ATC Abstracts

2016 American Transplant Congress
Safety, Efficacy, and Cost Saving Potential of Various Weight-Based Dosing for Thymoglobulin Induction Therapy in Kidney Transplant Recipients.
R. Miller,¹ H. Meadows,¹ S. Strout,¹ T. Veasey,¹ A. Mardis,¹ J. Fleming,¹ C. Mardis,¹ N. Pilch,¹ K. Chavin,² D. Taber.²
¹Department of Pharmacy, Medical University of South Carolina, Charleston, SC; ²Department of Surgery, Medical University of South Carolina, Charleston, SC.
Introduction: There are limited data assessing the appropriate weight to use when dosing Thymoglobulin for induction therapy. The aim of this study is to assess…
2016 American Transplant Congress
Virtual Crossmatching Under the New KAS: Safely Bypassing a Physical Crossmatch When Allocating Kidneys to Highly Sensitized Candidates.
R. Bray,¹ R. Parsons,² N. Turgeon,² H. Gebel.¹
¹Pathology, Emory University, Atlanta, GA; ²Emory Transplant Center, Emory University, Atlanta, GA.
AIM: On 12/4/2014, the OPTN implemented a new KAS for deceased donor(DD) transplants which, among many changes, increased priority for highly sensitized (HS) candidates (cPRA>98%).…
2016 American Transplant Congress
New Kidney Allocation System: Friend or Foe?
F. Cabeza,² A. Dejman,¹ A. Torres,³ J. Gaynor,² P. Ruiz,² D. Roth,² W. Kupin,² G. Burke,² G. Ciancio,² L. Chen,² R. Vianna,² A. Mattiazzi,² G. Guerra.²
¹Nephrology and Hypertension, University of Miami, Miami, FL; ²Kidney Transplant, Miami Transplant Institute, Miami, FL; ³Internal Medicine, Hospital San Jose Tec de Monterrey, Mexico D.F., Mexico.
BACKGROUND The new kidney allocation (KAS) system was implemented 12/2014 to increase recipient life years gained annually and facilitate the transplantation of harder to match…
2016 American Transplant Congress
Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Cold Ischemia Survival and Nuclear Co-Repressor Complex Expression.
D. Aufhauser Jr,¹ D. Murken,¹ Z. Wang,¹ A. Samanta,² G. Ge,¹ T. Bhatti,³ W. Hancock,^2,3 M. Levine.¹
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; ³Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.
Introduction: Class I histone/protein deacetylases (HDACs) 1 and 2 bear >85% protein sequence homology and conventionally are thought to have similar function via occupancy in…
2016 American Transplant Congress
Hydrogen Sulfide Treatment Mitigates Donor Tissue Necrosis During Prolonged Cold Storage and Improves Survival Following Allogeneic Renal Transplantation.
I. Lobb,^1,3 W. Liu,² J. Jiang,³ D. Lian,³ A. Sener.^1,3,4
¹Microbiology and Immunology, Western University Canada, London, ON, Canada; ²Pathology, Western University Canada, London, ON, Canada; ³Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ⁴Surgery, Western University Canada, London, ON, Canada.
Organ procurement is inherently associated with ischemia-reperfusion injury (IRI), resulting from loss and subsequent restoration of blood flow, which is detrimental to short- and long-term…
2016 American Transplant Congress
Health Insurance Trends in United States Living Kidney Donors.
J. Rodrigue,^1,2 A. Fleishman.¹
¹Surgery, Beth Israel Deaconess Medical Center, Boston, MA; ²Surgery, Harvard Medical School, Boston, MA.
The aim of this study was to examine health insurance trends in living kidney donors (LKDs) in the United States and their association with donor…
2016 American Transplant Congress
A Pilot Study of Donor: A Smart Phone Application for Identifying Live Kidney and Liver Donors.
K. Kumar,¹ E. King,¹ A. Muzaale,¹ J. Konel,¹ G. Segal,³ J. Arnold,³ K. Bramstedt,⁴ D. Segev,^1,2 A. Cameron.¹
¹Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ²Epidemiology, Johns Hopkins School of Public Health, Baltimore, MD; ³ORGANIZE, New York, NY; ⁴Bond University School of Medicine, Gold Coast, QLD, Australia.
Background: With over 100,000 candidates waiting, rates of deceased donation stagnant, and only 17,000 Kidney and liver transplants a year, live donor transplantation may represent…
2016 American Transplant Congress
An Assurance of Insurance: Should Living Kidney Donors Be Required to Have Health Insurance?
J. Siegel,¹ A. Humar,² P. Gianaros,¹ J. Steel.²
¹Department of Psychology, University of Pittsburgh, Pittsburgh, PA; ²Department of Surgery, Division of Transplantation, University of Pittsburgh, Pittsburgh, PA.
Lack of health insurance has been related lack of access to health care, poorer health, and increased mortality. In this study, we investigate sociodemographic predictors…
2016 American Transplant Congress
Associations of Perfusate Biomarkers and Pump Parameters with Delayed Graft Function and Deceased-Donor Kidney Allograft Function.
C. Parikh,¹ I. Hall,¹ R. Bhangoo,² J. Ficek,¹ P. Abt,³ H. Thiessen-Philbrook,¹ H. Lin,¹ M. Bimali,¹ P. Murray,⁴ V. Rao,¹ B. Schröppel,⁵ M. Doshi,⁶ F. Weng,⁷ P. Reese.³
¹Yale University School of Medicine, New Haven, CT; ²University of Arizona College of Medicine, Phoenix, AZ; ³University of Pennsylvania, Philadelphia, PA; ⁴University College Dublin, Dublin, Ireland; ⁵Mount Sinai School of Medicine, New York, NY; ⁶Wayne State University, Detroit, MI; ⁷Barnabas Health, Livingston, NJ.
Hypothermic machine perfusion (HMP) is increasingly used in deceased-donor kidney transplantation, but controversy exists regarding the value of perfusion biomarkers and pump parameters for assessing…
2016 American Transplant Congress
Don't Judge a Book by Its Cover: Normal Liver Enzymes After Transplantation Can Be Associated with Pathologies Requiring Intervention.
C. Sanchez,¹ S. Kumer,² S. Olson,¹ R. Gilroy,¹ T. Schmitt,² B. Kane,² R. Taylor.¹
¹Hepatology/Transplant, University of Kansas, Kansas City, KS; ²Surgery, University of Kansas, Kansas City, KS.
Background:Liver biopsies are employed post-transplant generally to evaluate abnormal liver enzymes (LE); however they are not without risk. Whether post-transplant protocol biopsies (PB) serve any…