ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Reduced-Dose Cidofovir (CID) and CMV-Hyperimmune Globulin (CMVIg) for Ganciclovir-Resistant Cytomegalovirus: Effective and Kidney Friendly.

    S. Patel, S. Kuten, J. Snyder, R. Knight, A. Gaber.

    Houston Methodist Hospital, Houston, TX.

    Ganciclovir resistant (GR) CMV is associated with an aggressive disease course and substantial morbidity. Furthermore, treatment options such as foscarnet and cidofovir are incredibly nephrotoxic.…
  • 2016 American Transplant Congress

    Characteristics of Human Rhinovirus (HRV) Infections in Transplant Recipients.

    H. Crossman,1 M. Barron,1 M. Levi.1

    1University of Colorado School of Medicine, Univ of Colorado Denver, Aurora, CO; 2Internal Medicine/Infectious Diseases, Univ of Colorado Denver, Aurora, CO; 3Internal Medicine/Infectious Diseases, Univ of Colorado Denver, Aurora, CO.

    Introduction:Although HRV is a common cause of benign upper respiratory infection, there are reports of HRV resulting in lower respiratory tract infection (LRTI) in HSCT…
  • 2016 American Transplant Congress

    Focal C4d Staining in Biopsies of Kidney Transplant Recipients Is Not Associated with Antibody Mediated Rejection and Does Not Correlate with Graft Survival.

    R. Prashar, M. Goggins, L. Yessayan, A. Patel, M. Goggins.

    Transplant Institute, Henry Ford Hospital, Detroit, MI.

    Introduction: While diffuse C4d positivity in kidney transplant peritubular capillaries(PTC) strongly co-relates with the presence of antibody mediated rejection(AMR),data on the significance of focal C4d…
  • 2016 American Transplant Congress

    The Early Outcomes of Bortezomib Therapy in Patients with Late Antibody Mediated Rejection in Renal Transplantation.

    J. Choi, J. Jung, S. Shin, Y. Kim, D. Han.

    Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

    Although several strategies for treating antibody mediated rejection (AMR) in renal transplants have been investigated, the formation of donor-specific antibodies (DSA) and ongoing AMR contribute…
  • 2016 American Transplant Congress

    The Therapeutic Potential of Human Liver-Derived Stem Cell Transplantation in a Cirrhotic Liver Rat Model.

    S. Lee,1 J.-H. Lee,2 H.-J. Park,2 Y.-A. Kim,2 M.-N. Park,2 S.-K. Lee.1

    1Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Stem Cell and Regenerative Medicine Center, Samsung Medical Center, Seoul, Republic of Korea.

    Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Previous studies suggested that MSCs may ameliorate fibrogenesis through…
  • 2016 American Transplant Congress

    IgM Treatment Successfully Prevents Type 1 Diabetes by Dysregulation of Pancreatic MicroRNAs with Immunomodulatory Roles.

    P. Chhabra, R. Gehrau, V. Mas, D. Bower, D. Maluf, K. Brayman.

    UVA, Charlottesville.

    Type 1 Diabetes (T1D) is hallmarked by beta-cells destruction. We aimed to identify specific pancreatic microRNAs (miRNA) as potential biomarkers for T1D prediction and diagnosis,…
  • 2016 American Transplant Congress

    Chemokine Receptor CXCR4 Antagonist, a Novel Pathway to Prevent Chronic Allograft Nephropathy.

    Y. Xu, Q. Zhang, X. Hu.

    Department of Urology, Beijing Chaoyang Hospital, Beijing, China.

    BackgroundChronic allograft nephropathy (CAN) remains a major problem for long term graft survival and different pathways participate in its development. CXC chemokine receptor 4 (CXCR4)…
  • 2016 American Transplant Congress

    Memory Regulatory T Cell: A Potential Actor in Immunological Operational Tolerance in Kidney-Transplant Patients via the ATP Degradation into Adenosine.

    M. Durand,1,2 F. Braza,1 N. Degauque,1 F. Dubois,2 M. Chesneau,1 P. Guérif,1,3 M. Giral,1,3 S. Brouard.1

    1ITUN-INSERM U1064, Nantes, France; 2University of Nantes, Nantes, France; 3Biotherapy Clinical Investigation Center, Nantes, France.

    Regulatory T cells (Tregs) are essential actors in the control of self-tolerance and exacerbated inflammation. In experimental transplantation Tregs are critical to achieve alloantigen tolerance…
  • 2016 American Transplant Congress

    Outcomes of Untreated Asymptomatic Bacteriuria in Renal Transplant Recipients: A Single-Center Experience.

    W. Davis, R.-A. Lee, L. Daniels, S. Todd, K. True, P. Chong.

    University of North Carolina Medical Center, Chapel Hill, NC.

    Background. Renal transplant recipients (RTR) with asymptomatic bacteriuria (AB) are often treated with antibiotics. This could lead to complications related to antibiotic treatment including Clostridium…
  • 2016 American Transplant Congress

    The Effect of the Use of a TNF-Alpha Inhibitor in Hypothermic Machine Perfusion on Kidney Function After Transplantation.

    P. Diuwe,1 P. Domagala,1 R. Kieszek,1 M. Wszola,1 M. Serwanska-Swietek,1 L. Paczek,2 M. Durlik,3 A. Chmura,1 A. Kwiatkowski.1

    1Department of General Surgery and Transplantology, Medical University of Warsaw, Warsaw, Poland; 2Department of Immunology, Transplantology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland; 3Department of Transplantology and Nephrology, Medical University of Warsaw, Warsaw, Poland.

    Organ damage associated with processes occurring during the ischaemic period as well as during and after organ reperfusion is an important problem of transplantation medicine.The…
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