ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Stress Cardiomyopathy in the Perio-Perative Period After Liver Transplant.

    N. Presser, B. Barzilai.

    General Surgery, Clevelanc Clinic Foundation, Cleveland, OH; Cardiology, Cleveland Clinic Foundation, Cleveland, OH.

    Purpose: Stress cardiomyopathy is a pathological condition in which excess catecholamines leading to cardiac dysfunction. This phenomenon is associated with troponin elevation, EKG changes, and…
  • 2016 American Transplant Congress

    Mycophenolate Mofetil Single Dose Pharmacokinetics Following Laparoscopic Sleeve Gastrectomy.

    A. Leino,1 A. Lichvar,1 T. Kaiser,1 U. Christians,3 T. Mizuno,2 T. Fukuda,2 R. Alloway,1 A. Vinks,2 E. Woodle,1 T. Diwan.1

    1U of Cincinnati, Cincinnati; 2Cincinnati Children's Hospital, Cincinnati; 3U of Colorado Health Sciences Center, Denver.

    The influence of various metabolic surgery procedures on immunosuppressant pharmacokinetics (PK) is largely unknown. For laparoscopic sleeve gastrectomy (LSG) (currently the most common procedure) no…
  • 2016 American Transplant Congress

    Common Iliac Artery Stenosis: An Often Overlooked Cause of Graft Dysfunction.

    E. Christie, P. Campbell, K. Wen.

    Nephrology, University of Alberta, Edmonton, AB, Canada.

    Transplant renal artery stenosis (TRAS) has been an increasingly recognized complication post kidney transplantation, and a potentially reversible cause for hypertension and allograft dysfunction. This…
  • 2016 American Transplant Congress

    Age Adapted Immunosuppression for Elderly Kidney Allograft Recipients: Balancing Risks for Cancer versus Rejection.

    F. Jackson-Spence,1 H. Gillott,1 S. Tahir,1 F. Evison,2 J. Nath,3 A. Sharif.3

    1University of Birmingham Medical School, Birmingham, United Kingdom; 2Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

    Introduction Cancer is a growing cause of morbidity and mortality after kidney transplantation, driven by immunosuppression. Age is one of the strongest risk factors for…
  • 2016 American Transplant Congress

    Implementation of a Risk Stratified Approach for Prevention of Hepatitis B Reactivation Post Kidney Transplant.

    M. Cote,1 M. Pavlakis,2 J. Ethridge,1 C. Currier,2 M. Curry,2 E. Khankin,2 F. Cardarelli,2 K. Richards,1,2 C. Rogers.1,2

    1Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston; 2Transplant Institute, Beth Israel Deaconess Medical Center, Boston.

    A large percentage of patients with end stage renal disease are known to be Hepatitis B virus (HBV) positive. A 2015 consensus guideline on use…
  • 2016 American Transplant Congress

    Direct Detection of T and B Memory Lymphocytes Reveals HCMV Exposure That Serum Antibodies Fail to Identify.

    S. Sundararaman, F. Terlutter, T. Nowacki, R. Caspell, P. Lehmann.

    Research and Development, Cellular Technology Ltd, Shaker Hts, OH.

    It is essential to identify donors who have not been infected with HCMV in order to avoid transmission of HCMV to human recipients of transfusion…
  • 2016 American Transplant Congress

    Impact of C3d and C1q-Binding DSA Detected Long-Term After Kidney Transplantation.

    M. Crespo,1,2 D. Redondo,1,2 C. Garcia,3 J. Gimeno,4 M. Perez,1,2 M. Mir,1 J. Hernandez,3 J. Yelamos,2 A. Faura,1,2 J. Pascual.1,2

    1Nephrology and Transplant, Hospital del Mar, Barcelona, Spain; 2Medical Research Institute (IMIM), Hospital del Mar, Barcelona, Spain; 3Catalunya Reference Laboratory, Barcelona, Spain; 4Pathology, Hospital del Mar, Barcelona, Spain.

    HLA DSA detected after kidney transplantation(KT) correlate with outcome, but not all are equal and produce the same functional consequences. Early complement-binding DSA were asssociated…
  • 2016 American Transplant Congress

    Elevation of Peripheral IL-6 in Kidney Transplant Recipients with Antibody Mediated Rejection.

    N. Wilson, A. Djamali, R. Redfield.

    University of Wisconsin, Madison.

    Background: Despite current therapy, antibody mediated rejection (AMR) remains a major cause of kidney allograft loss. IL-6 is a known survival factor of antibody secreting…
  • 2016 American Transplant Congress

    Mechanisms of Cellular Repopulation within Healthy or Intrinsically Scarred Kidney Extracellular Matrix Scaffolds.

    J. Uzarski,1 C. Deaton,5 H. Ward,2 A. Wandinger-Ness,3 W. Miller,4 J. Wertheim.1

    1Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL; 2Department of Internal Medicine, University of New Mexico HSC, Albuquerque, NM; 3Department of Pathology, University of New Mexico HSC, Albuquerque, NM; 4Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL; 5Department of Biology, University of Mexico, Albuquerque, NM.

    Background: While the number of wait-listed patients suffering from kidney failure continues to rise, the number of kidney transplants performed each year has remained stagnant.…
  • 2016 American Transplant Congress

    Monocyte Recruitment to HLA Class I Antibody-Activated Endothelial Cells Is Dependent Upon mTOR.

    S. Salehi, E. Reed.

    Pathology & Laboratory Medicine, UCLA, Los Angeles, CA.

    Aim: Antibody-mediated rejection (AMR) is a major issue affecting solid organ transplants, manifesting with recruitment of monocytes to the endothelium of the allograft. The purpose…
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