2016 American Transplant Congress
Characteristics Independently Associated with Kidney Candidates Having CPRA of 99-100%.
Background: The new Kidney Allocation System (KAS) implemented on 12/4/14 included an increased allocation priority for candidates with CPRA 99-100%. On 11/30/14, just days prior…2016 American Transplant Congress
Correlation of the Shear Wave Elastography with Renal Function in Kidney Transplant Recipients: A Proof of Concept Study.
Background: Non-invasive biomarker for kidney allograft fibrosis is needed. Shear wave elastography is a relatively new technique to assess tissue stiffness. Graft rejection and chronic…2016 American Transplant Congress
Number of Bacterial Isolates and Resistance Increases Mortality Risk in Intestinal Transplant Patients.
Icahn School of Medicine at Mount Sinai, New York.
BackgroundInfection is the most common complication in intestinal transplant (IT) recipients. Data regarding the impact of infections on outcomes following IT is limited.MethodsThis is a…2016 American Transplant Congress
Donor Sharpin Expression Modulates TNFα Mediated Inflammation and Cardiac Allograft Rejection in Mice.
Increased systemic TNFα levels correlate with transplant rejection and severity of GVHD, and TNFα blockade can prolong graft survival and reduce severity of GVHD. These…2016 American Transplant Congress
CMV-Accelerated Cardiac Allograft Rejection Is Associated with Dysregulation of Sphingolipid Metabolomics.
PurposeCytomegalovirus (CMV) infection accelerates transplant vascular sclerosis (TVS) and chronic rejection (CR) in solid organ transplants. Sphingolipid metabolism plays an immunomodulatory role in transplant rejection,…2016 American Transplant Congress
Long Term Heterotopic Cardiac Xenograft Survival from Donor Pigs with Six Gene Modifications.
1CSRP, NHLBI/NIH, Bethesda, MD; 2DVR / RS, NIH, Bethesda, MD; 3Revivicor, Inc, Blacksburgh, VA.
Introduction: We have recently reported pig xenograft survival of more than 2.5 years in a heterotopic cardiac xenograft model. Some of the animals exhibited local…2016 American Transplant Congress
Non-adherence to Appointments Is a Strong Predictor of Medication Non-Adherence and Outcomes in Kidney Transplant Recipients.
Medical University of South Carolina, Charleston, SC.
Disparities in healthcare access and non-adherence are important aspects of transplantation that affect outcomes. This study aims to investigate the impact of non-adherence to laboratory…2016 American Transplant Congress
A 15-Year Retrospective Analysis of Acute Kidney Injury in Non Renal Solid Organ Transplant Recipients: Incidence, Outcome and Progression Toward End Stage Chronic Kidney Disease.
Acute kidney injury (AKI) is a frequent complication in critically ill patients admitted to Intensive Care Units, often complicated by high mortality and progression toward…2016 American Transplant Congress
Difficult to Place Livers: Implications for Expanding the Donor Pool.
1United Network for Organ Sharing, Richmond, VA; 2Methodist University Hospital, Memphis, TN.
Introduction. The primary strategic goal for the OPTN is to increase the number of transplants. To that end, we analyzed the characteristics of donors from…2016 American Transplant Congress
Donor Smoking Increases Kidney Allograft Recipient Mortality in a National Population Cohort Analysis.
Introduction: Current evidence from single-centre analyses suggest cigarette smoking in living donors is associated with worse patient but not graft survival in kidney allograft recipients.…
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