Am J Transplant, Volume 16, Suppl 3 Archives - Page 137 of 180 - ATC Abstracts

2016 American Transplant Congress
Adding Anti-Inflammatory Agents During Normothermic Ex-Vivo Liver Perfusion Improves the Preservation of Pig Liver Grafts Before Transplantation.
N. Goldaracena, E. Juan, K. Moritz, V. Spetzler, A. Barbas, D. Grant, M. Selzner.
Multi Organ Transplant Program, Toronto General Hospital, Toronto, Canada.
Introduction: Normothermic ex vivo liver perfusion (NEVLP) improves graft preservation by avoiding cold ischemic injury. We investigated if protective effects of NEVLP can be further…
2016 American Transplant Congress
Interaction Between Kidney Tissue Proteome and Humoral Immunity in Antibody Mediated Rejection.
A. Konvalinka,¹ A. Chruscinski,² S. Kim,¹ K. Tinckam,¹ I. Jurisica,³ R. John.⁴
¹Medicine/Division of Nephrology, Toronto General Hospital, Toronto, ON, Canada; ²Medicine/Division of Cardiology, Toronto General Hospital, Toronto, ON, Canada; ³Medical Biophysics and Computational Science, University of Toronto, Toronto, ON, Canada; ⁴Pathology, Toronto General Hospital, Toronto, ON, Canada.
PURPOSE: Antibody-mediated rejection (AMR) is caused by antibodies against human leukocyte antigens (HLA) on graft endothelium, and non-HLA antibodies that target endothelial and epithelial proteins.…
2016 American Transplant Congress
Resveratrol Effectively Suppress Th17 Associated Allo-Immune Responses by the Modulation of AMPK/mTOR Pathway.
B. Chung, K. Doh, J.-W. Min, K. Kim, B.-M. Kim, M.-L. Cho, C. Yang.
Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
The aim of this study is to investigate the effect of resveratrol on Th17 allo-immune responses under tacrolimus (Tac)-based immune suppression. First, we investigated the…
2016 American Transplant Congress
HLA Antibody Clonality and Epitopes Dictate Complement Activation.
K. Thomas,¹ N. Valenzuela,¹ A. Mulder,² E. Reed.¹
¹Pathology and Laboratory Medicine, UCLA, Los Angeles, CA; ²Leiden University Medical Center, Leiden, Netherlands.
Background: Alloimmunization results in production of polyclonal donor specific antibodies (DSA) against human leukocyte antigens (HLA), which mediate endothelial cell activation, leukocyte recruitment, and complement…
2016 American Transplant Congress
Concordance Between Pancreatic Rejection and Kidney Rejection and Kidney Survival in Simultaneous Pancreas Kidney Transplantation.
I. Moinuddin, T. Taber, M. Yaqub, D. Mishler, O. Adebiyi, J. Chen, M. Goble, J. Powelson, J. Fridell, A. Sharfuddin.
Transplant Nephrology, Indiana University, Indianapolis, IN.
Purpose: It is not known whether pancreas rejection is associated with increased kidney rejection. Also, it is not known whether pancreas survival affects kidney and…
2016 American Transplant Congress
Validation of SUITO Index and C-Peptide/Glucose Creatinine Ratio as Convenient Tools for the Evaluation of the Short and Long-Term Islet Allograft Function.
J. Gołębiewska,¹ J. Solomina,² S. Matosz,² C. Thomas,³ L. Schenck,² K. Golab,² W. Chon,³ S. Ramachandran,² M. Tibudan,² A. Dębska-ŚLizień,¹ B. Rutkowski,¹ P. Witkowski.²
¹Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdańsk, Gdańsk, Poland; ²Department of Surgery, University of Chicago, Chicago, IL; ³Department of Medicine, University of Chicago, Chicago, IL.
Background: Mixed Meal Tolerance Test (MMTT) together with the beta-score are standard tools to evaluate beta-cell function after islet transplantation but utilization of the test…
2016 American Transplant Congress
The In Vivo Non-Invasive Long-Term Functional Assessment of Neuronal Regeneration in Vascularized Composite Allotransplantation.
C.-J. Wen,^1,2 C.-H. Lin,¹ S.-L. Peng,^3,4 F.-N. Wang,³ L.-Y. Huang,³ H.-Y. Cheng,¹ H.-H. Hsu,¹ X.-T. Huang,¹ C.-H. Lin,¹ F.-C. Wei.¹
¹Center for Vascularized Composite Allotransplantation, Chang Gung Medical Foundation, Taoyuan, Taiwan; ²Department of Medicine, Chang Gung University, Taoyuan, Taiwan; ³Department of Biomedical Engineering and Environmental Sciences, Tsing Hua University, Hsinchu, Taiwan; ⁴Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan.
The neuronal regeneration is a key issue of vascularized composite allotransplantation (VCA).As for the generally used functional observations, behavior testing or invasive functional inspection (e.g.…
2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
A. DeMers, R. Forbes, D. Moore, K. Smith, D. Shaffer.
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…
2016 American Transplant Congress
Long Term Follow Up of Kidney Donors with Asymptomatic Renal Stones.
D. Serur,¹ M. Charlton,² K. Juluru,³ G. Salama,³ E. LoCastro,³ G. Bretzlaff,² C. Hartono.¹
¹Nephrology/Rogosin, New York Presbyterian Weill Cornell, New York, NY; ²Kidney and Pancreas Transplantation, New York Presbyterian Weill Cornell, New York, NY; ³Radiology, New York Presbyterian Weill Cornell, New York, NY.
BACKGROUND:Kidney stones are often found incidentally in potential renal donors and there is a concern that they may become symptomatic and cause damage in the…
2016 American Transplant Congress
Urinary Exosomal Annexin A1 Is a Predictive Biomarker of Post Kidney Transplant Complications.
H. Harada,¹ T. Murakami,² C. Yamamoto,² K. Hotta,¹ N. Fukuzawa,¹ M. Mitsuhashi.²
¹Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan; ²Hitachi Chemical Co. America, Ltd., Irvine, CA; ³Nanosomix, Inc., Aliso Viejo, CA.
IntroductionMonitoring of kidney allograft condition is important. We had exhibited non-invasive diagnostic modality of post-kidney transplant complications using urine exosomal and microvesicule (EMV) mRNA of…