2016 American Transplant Congress
Center-Level Variation in Association Between Early Hospital Readmission and Survival Following Kidney Transplantation.
Department of Surgery, Johns Hopkins, Baltimore.
Background: Early hospital readmission (EHR) following kidney transplantation (KT) is associated with inferior survival. However, incidence of EHR varies significantly across center following KT. Recent…2016 American Transplant Congress
Sociodemographic and Comorbidity Differences Between Dialysis, Waitlisted and Transplant Patients in the UK: Findings from the ATTOM Study.
IntroductionAccess to Transplantation and Transplant Outcome Measures (ATTOM) is a prospective cohort study involving all 72 UK renal units, investigating factors affecting access to and…2016 American Transplant Congress
Results of a Phase 1 Trial of Treg Adoptive Cell Transfer (TRACT) in De Novo Living Donor Kidney Transplant Recipients.
1Northwestern University, Chicago; 2NMH, Chicago; 3TRACT Therapeutics, Chicago.
Therapeutic cell transfer using regulatory T cells (Tregs) holds the promise of reducing the need for drug based immunosuppression (IS) and improving long term graft…2016 American Transplant Congress
Modified Normothermic Extracorporeal Liver Perfusion for Discarded Human Livers.
Introduction: Donor organ shortages have led to increased interest in finding new approaches to recover organs from extended criteria donors (ECD). Normothermic ex-vivo liver perfusion…2016 American Transplant Congress
Tracking of Endogenous Graft-Reactive Tregs Reveals Their Peripheral Enrichment During Transplantation Tolerance.
Purpose: Our goal for this study was to determine the relative fates of endogenous Foxp3- conventional (Tconv) and Foxp3+ regulatory T cells (Tregs) specific for…2016 American Transplant Congress
Enhanced IL-6 Production Impedes Transplant Tolerance Induction in Lupus-Prone Mice.
Pediatrics and Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN.
Significance: Autoimmunity is a significant barrier to transplantation. Based on previous studies, it is apparent that there are separate genetic regions that control susceptibility to…2016 American Transplant Congress
Pregnancy Outcomes in 17 Female Heart Transplant Recipients with the Initial Diagnosis of Congenital Heart Defect.
The purpose of this study was to describe pregnancy in female heart recipients whose indication for transplantation was due to congenital heart defect. Data were…2016 American Transplant Congress
How Did the New Kidney and Pancreas Allocation Systems Effect Pancreas Utilization in the First Six-Months?
Background: In 2010 a new pancreas allocation system (PAS) was approved by the OPTN and implemented in October 2014, shortly preceding the new kidney allocation…2016 American Transplant Congress
Differential Regulation of the Microvascular Endothelial Cell Mediated Allogeneic CD4+ T Cell Response by Anti-HLA-DR and -DQ Alloantibodies in an Inflammatory Context.
This study examines the basic mechanisms by which high levels of circulating HLA class II donor-specific-antibodies can contribute to microvasculature damage in chronic antibody mediated…2016 American Transplant Congress
Characterization of Human Islet Transplant Specific Exosomes in a Xenoislet Transplantation Model.
Department of Surgery, University of Pennsylvania, Philadelphia, PA.
Background: There is a critical need for biomarker platforms for monitoring transplant rejection. We propose that transplant tissues release donor specific exosomes into recipient blood/…
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