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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Adherence Patterns in Adolescent and Young Adult Kidney Transplant Recipients.

    J. Boucquemont,1,2 B. Foster,1,2 The TAKE-IT Investigators.

    1Research Inst. of the McGill Univ. Health Centre, Montréal, QC, Canada; 2Dept of Epidemiology, Biostatistics and Occupational Health, McGill Univ., Montreal, QC, Canada.

    Poor adherence to immunosuppressive medications limits long-term renal allograft survival. Using data from the 3-month run-in (no intervention) of the randomized trial TAKE-IT, which tests…
  • 2016 American Transplant Congress

    The Impact of Readmission following Kidney Transplantation: Is Readmission Becoming More Risky?

    E. King, L. Kucirka, M. McAdams-DeMarco, A. Massie, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: Following kidney transplantation, 31% of recipients experience early hospital readmission (EHR) and readmission is independently associated with increased risk of graft loss and mortality.…
  • 2016 American Transplant Congress

    Sirolimus Regimen and Viral Serology as Risk Factors for Outcomes of Adult Kidney Transplants: 14-Year Cumulative Data in the United States.

    A. Santos, M. Casey, X. Wen, S. Rehman, K. Womer.

    Department of Medicine, Univ. of Florida, College of Medicine, Gainesville, FL.

    BACKGROUND: The relative risks for patient mortality, graft loss and malignancy in the five years following kidney-only transplant (KT) based on sirolimus (SRL) regimen at…
  • 2016 American Transplant Congress

    Treatments Against Renin-Angiotensin-Aldosterone System Could Influence FGF23 and Klotho Levels in Renal Transplant Recipients.

    S. Sezer,1 E. Tutal,1 Z. Bal,1 M. Uyar,1 M. Haberal.2

    1Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey; 2General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

    Purpose: Angiotensin-converting enzyme inhibitor ( ACEI) and angiotensin II receptor blocker (ARB) are frequently used in post transplant hypertension. Recent trials reported that renin-angiotensin-aldosterone system…
  • 2016 American Transplant Congress

    Outcomes of Depleting Antibody Induction in Kidney Transplantation: A Paired Kidney Analysis.

    M. Sampaio, B. Chopra, K. Sureshkumar.

    Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.

    Induction therapy can improve graft survival following kidney transplantation. Organ quality, a major determinant of graft outcomes may act as a confounder in comparative studies…
  • 2016 American Transplant Congress

    Utility of Six-Minute-Walk Distance in Predicting Lung Transplant Benefit in the Lung Allocation Score Era.

    S. Shah,1 D. Tumin,3 B. Whitson,2 A. Pope-Harman,1 S. Kirkby,1 A. Kilic,2 P. Lee,2 D. Hayes.1,3

    1Pulmonary and Critical Care, Ohio State University Wexner Medical Center, Columbus, OH; 2Division of Cardiac Surgery, Ohio State University Wexner Medical Center, Columbus, OH; 3Pediatrics, Ohio State University, Columbus, OH.

    Transplant physicians evaluate patients for lung transplant (LTx) who are on ventilators and ECMO with high lung allocation scores (LAS). Six-minute walk distance (6MWD) predicts…
  • 2016 American Transplant Congress

    Combination of Veto Cell Transfer and iNKT Cell Therapy Establishes Complete Hematopoietic Chimerism in Non-Myeloablative BMT Recipients.

    R. Ishii,1 T. Hirai,1 Y. Ishii,2 K. Tanabe.1

    1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Laboratory for Vaccine Design, RIKEN IMS-RCAI, Yokohama, Japan.

    Hematopoietic chimerism after non-myeloablative bone marrow transplantation (nmBMT) has been found beneficial for establishment of transplant tolerance. Since bone marrow cells (BMCs) are endowed with…
  • 2016 American Transplant Congress

    Would Transplanting Kidneys Currently Being Discarded in the US Place Programs at Risk for Regulatory Review?

    J. Snyder, N. Salkowski, B. Thompson, A. Wey, A. Israni, B. Kasiske, S. Leppke.

    Scientific Registry of Transplant Recipients, Minneapolis.

    In the US in 2014, 17,188 potential kidneys were available from 8594 deceased donors (2014 SRTR/OPTN Annual Data Report). Of these, 25% were not recovered…
  • 2016 American Transplant Congress

    Comparison of C4d Deposition in Renal Biopsies with Luminex-Based C3d Single Antigen Bead (SAB) Detection.

    R. Pelletier,1 I. Balazs,2 P. Adams,3 P. Steller,3 N. DiPaola,4 L. Rankin,3 A. Diez,5 M. Henry.1

    1Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Discovery Research, Immucor, Inc, Stamford, CT; 3Tissue Typing, The Ohio State University Wexner Medical Center, Columbus, OH; 4Methodist Hospital, Houston, TX; 5Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH.

    Recent interest in characterizing the complement-fixing ability of post-transplant donor specific alloantibodies (DSA) resulted in the enhancement of luminex solid phase alloantibody assays to determine…
  • 2016 American Transplant Congress

    Polyclonal Treg Adoptive Therapy for Control of Subclinical Kidney Transplant Inflammation (TASK Pilot Trial).

    S. Chandran, Q. Tang, M. Sarwal, Z. Laszik, A. Putnam, T. Sigdel, E. Tavares, J. Bluestone, F. Vincenti.

    UCSF, San Francisco, CA.

    Purpose: Early renal graft inflammation is associated with progressive fibrosis & late dysfunction. Treg therapy can reverse established inflammation in animal models. We conducted a…
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